Therapeutic target database update 2012: a resource for facilitating target-oriented drug discovery

Trends in the exploitation of novel drug targets

(2011) Mathias Rask-Andersen et al.   NATURE REVIEWS DRUG DISCOVERY

Clustered patterns of species origins of nature-derived drugs and clues for future bioprospecting

(2011) F. Zhu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

QSAR in the Pharmaceutical Research Setting: QSAR Models for Broad, Large Problems

(2010) D.G. Sprous et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Virtual Screening of Selective Multitarget Kinase Inhibitors by Combinatorial Support Vector Machines

(2010) X. H. Ma et al.   MOLECULAR PHARMACEUTICS

Development trends for human monoclonal antibody therapeutics

(2010) Aaron L. Nelson et al.   NATURE REVIEWS DRUG DISCOVERY

DrugBank 3.0: a comprehensive resource for 'Omics' research on drugs

(2010) C. Knox et al.   NUCLEIC ACIDS RESEARCH

Database resources of the National Center for Biotechnology Information

(2010) E. W. Sayers et al.   NUCLEIC ACIDS RESEARCH

In-Silico Approaches to Multi-target Drug Discovery

(2010) Xiao Hua Ma et al.   PHARMACEUTICAL RESEARCH

The basics of preclinical drug development for neurodegenerative disease indications

(2009) Karen L Steinmetz et al.   BMC Neurology

Challenges in Analgesic Drug Development

(2009) D J Hewitt et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

In vivo target validation using gene invalidation, RNA interference and protein functional knockout models: it is the time to combine

(2009) Olivier Vidalin et al.   CURRENT OPINION IN PHARMACOLOGY

Comparison Data Sets for Benchmarking QSAR Methodologies in Lead Optimization

(2009) Ruchi R. Mittal et al.   Journal of Chemical Information and Modeling

ChEMBL. An interview with John Overington, team leader, chemogenomics at the European Bioinformatics Institute Outstation of the European Molecular Biology Laboratory (EMBL-EBI)

(2009) Wendy A. Warr   JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN

What Are Next Generation Innovative Therapeutic Targets? Clues from Genetic, Structural, Physicochemical, and Systems Profiles of Successful Targets

(2009) F. Zhu et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Mechanisms of drug combinations: interaction and network perspectives

(2009) Jia Jia et al.   NATURE REVIEWS DRUG DISCOVERY

Update of TTD: Therapeutic Target Database

(2009) Feng Zhu et al.   NUCLEIC ACIDS RESEARCH

Drug Discovery and Natural Products: End of an Era or an Endless Frontier?

(2009) J. W.-H. Li et al.   SCIENCE

Natural products to drugs: natural product-derived compounds in clinical trials

(2008) Mark S. Butler   NATURAL PRODUCT REPORTS

Killing two kinase families with one stone

(2008) Benoit Bilanges et al.   Nature Chemical Biology

Plant-derived compounds in clinical trials

(2007) A SAKLANI et al.   DRUG DISCOVERY TODAY