Anti-Atherogenic Effect of Laminar Shear Stress via Nrf2 Activation

Key transcriptional regulators of the vasoprotective effects of shear stress

(2018) R. A. Boon et al.   Hamostaseologie

Animal, In Vitro, and Ex Vivo Models of Flow-Dependent Atherosclerosis: Role of Oxidative Stress

(2010) Amir Rezvan et al.   ANTIOXIDANTS & REDOX SIGNALING

“Go With the Flow”: How Krüppel-Like Factor 2 Regulates the Vasoprotective Effects of Shear Stress

(2010) Lalitha Nayak et al.   ANTIOXIDANTS & REDOX SIGNALING

Flow Shear Stress and Atherosclerosis: A Matter of Site Specificity

(2010) Patrizia Nigro et al.   ANTIOXIDANTS & REDOX SIGNALING

Role of MCP-1 in tumor necrosis factor-α-induced endothelial dysfunction in type 2 diabetic mice

(2009) Jiyeon Yang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Endothelial cell responses to atheroprone flow are driven by two separate flow components: low time-average shear stress and fluid flow reversal

(2009) Daniel E. Conway et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Nitric Oxide, NAD(P)H Oxidase, and Atherosclerosis

(2009) Gregor Muller et al.   ANTIOXIDANTS & REDOX SIGNALING

Understanding peroxynitrite biochemistry and its potential for treating human diseases

(2009) Joseph S. Beckman   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Flow Activation of AMP-Activated Protein Kinase in Vascular Endothelium Leads to Krüppel-Like Factor 2 Expression

(2009) Angela Young et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Activation of Nrf2 in Endothelial Cells Protects Arteries From Exhibiting a Proinflammatory State

(2009) Mustafa Zakkar et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Mitochondria-Derived Reactive Oxygen Species Mediate Heme Oxygenase-1 Expression in Sheared Endothelial Cells

(2009) Z. Han et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Shear stress influences spatial variations in vascular Mn-SOD expression: implication for LDL nitration

(2008) Lisong Ai et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Endothelial cell respiration is affected by the oxygen tension during shear exposure: role of mitochondrial peroxynitrite

(2008) Charles I. Jones et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Nitric oxide-dependent stimulation of endothelial cell proliferation by sustained high flow

(2008) Eleni Metaxa et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

NADPH oxidase has a directional response to shear stress

(2008) Anjali S. Godbole et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

KLF2 Primes the Antioxidant Transcription Factor Nrf2 for Activation in Endothelial Cells

(2008) Joost O. Fledderus et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Collateral circulation

(2008) Wolfgang Schaper   BASIC RESEARCH IN CARDIOLOGY

Accumulation of 15-deoxy-Δ12,14-prostaglandin J2adduct formation with Keap1 over time: effects on potency for intracellular antioxidant defence induction

(2008) Joo Yeun Oh et al.   BIOCHEMICAL JOURNAL

Covalent Modification at Cys151 Dissociates the Electrophile Sensor Keap1 from the Ubiquitin Ligase CUL3

(2008) Girish Rachakonda et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Human neutrophil–pulmonary microvascular endothelial cell interactions in vitro: Differential effects of nitric oxide vs. peroxynitrite

(2008) Jennifer L. Shelton et al.   MICROVASCULAR RESEARCH

Physiological Significance of Reactive Cysteine Residues of Keap1 in Determining Nrf2 Activity

(2008) T. Yamamoto et al.   MOLECULAR AND CELLULAR BIOLOGY

The Antioxidant Defense System Keap1-Nrf2 Comprises a Multiple Sensing Mechanism for Responding to a Wide Range of Chemical Compounds

(2008) M. Kobayashi et al.   MOLECULAR AND CELLULAR BIOLOGY

Keap1 modification and nuclear accumulation in response to S-nitrosocysteine

(2007) Barbara J. Buckley et al.   FREE RADICAL BIOLOGY AND MEDICINE

Carnosic acid, acatechol-typeelectrophilic compound, protects neurons bothin vitroandin vivothrough activation of the Keap1/Nrf2 pathway viaS-alkylation of targeted cysteines on Keap1

(2007) Takumi Satoh et al.   JOURNAL OF NEUROCHEMISTRY