Shear stress mediates exocytosis of functional TRPV4 channels in endothelial cells

The proteins of exocytosis: lessons from the sperm model

(2015) Claudia Nora Tomes   BIOCHEMICAL JOURNAL

Functional transient receptor potential vanilloid 1 and transient receptor potential vanilloid 4 channels along different segments of the renal vasculature

(2014) L. Chen et al.   Acta Physiologica

Examination of the role of transient receptor potential vanilloid type 4 in endothelial responses to shear forces

(2014) Sara Baratchi et al.   Biomicrofluidics

Piezo1, a mechanically activated ion channel, is required for vascular development in mice

(2014) S. S. Ranade et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TRPV4-mediated mechanotransduction regulates the metabolic response of chondrocytes to dynamic loading

(2014) C. J. O'Conor et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

AKAP150-dependent cooperative TRPV4 channel gating is central to endothelium-dependent vasodilation and is disrupted in hypertension

(2014) S. K. Sonkusare et al.   Science Signaling

In Silico Modeling of Shear-Stress-Induced Nitric Oxide Production in Endothelial Cells through Systems Biology

(2013) Andrew Koo et al.   BIOPHYSICAL JOURNAL

The puzzle of TRPV4 channelopathies

(2013) Bernd Nilius et al.   EMBO REPORTS

A TRPV4 Channel C-terminal Folding Recognition Domain Critical for Trafficking and Function

(2013) Lei Lei et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Discrete Control of TRPV4 Channel Function in the Distal Nephron by Protein Kinases A and C

(2013) Mykola Mamenko et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Protease-activated Receptor 2 (PAR2) Protein and Transient Receptor Potential Vanilloid 4 (TRPV4) Protein Coupling Is Required for Sustained Inflammatory Signaling

(2013) Daniel P. Poole et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Piezo proteins are pore-forming subunits of mechanically activated channels

(2012) Bertrand Coste et al.   NATURE

Novel insights into TRPV4 function in the kidney

(2012) Oleh Pochynyuk et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Endogenous viral antigen processing generates peptide-specific MHC class I cell-surface clusters

(2012) X. Lu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Elementary Ca2+ Signals Through Endothelial TRPV4 Channels Regulate Vascular Function

(2012) S. K. Sonkusare et al.   SCIENCE

An Orally Active TRPV4 Channel Blocker Prevents and Resolves Pulmonary Edema Induced by Heart Failure

(2012) Kevin S. Thorneloe et al.   Science Translational Medicine

Identification and Characterization of a Novel Integrin-Linked Kinase Inhibitor

(2011) Su-Lin Lee et al.   JOURNAL OF MEDICINAL CHEMISTRY

Dynamic molecular processes mediate cellular mechanotransduction

(2011) Brenton D. Hoffman et al.   NATURE

Molecular mechanisms of mechanotransduction in mammalian sensory neurons

(2011) Patrick Delmas et al.   NATURE REVIEWS NEUROSCIENCE

TRPV4 mediates tumor-derived endothelial cell migration via arachidonic acid-activated actin remodeling

(2011) A Fiorio Pla et al.   ONCOGENE

Spatial association of the Cav1.2 calcium channel with α5β1-integrin

(2010) Jun-Tzu Chao et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Presynaptic calcium channels and α3-integrins are complexed with synaptic cleft laminins, cytoskeletal elements and active zone components

(2010) Steven S. Carlson et al.   JOURNAL OF NEUROCHEMISTRY

Importance of Non-Selective Cation Channel TRPV4 Interaction with Cytoskeleton and Their Reciprocal Regulations in Cultured Cells

(2010) Chandan Goswami et al.   PLoS One

Integrin linked kinase (ILK) expression and function in vascular smooth muscle cells

(2010) Bernard Ho et al.   Cell Adhesion & Migration

TRPV4-mediated endothelial Ca2+ influx and vasodilation in response to shear stress

(2009) Suelhem A. Mendoza et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Cross-Talk Between PKA and Akt Protects Endothelial Cells From Apoptosis in the Late Ischemic Preconditioning

(2009) Alessandro Bellis et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Exocytosis of Post-Golgi Vesicles Is Regulated by Components of the Endocytic Machinery

(2009) Jyoti K. Jaiswal et al.   CELL

TRPV4 Channels Mediate Cyclic Strain–Induced Endothelial Cell Reorientation Through Integrin-to-Integrin Signaling

(2009) Charles K. Thodeti et al.   CIRCULATION RESEARCH

Activation of the TRPV4 Ion Channel Is Enhanced by Phosphorylation

(2009) Hueng-Chuen Fan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Role of Rac 1 and cAMP in endothelial barrier stabilization and thrombin-induced barrier breakdown

(2009) Y. Baumer et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Rho signaling and mechanical control of vascular development

(2008) Akiko Mammoto et al.   CURRENT OPINION IN HEMATOLOGY

Functional interaction of the cation channel transient receptor potential vanilloid 4 (TRPV4) and actin in volume regulation

(2008) Daniel Becker et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Tyrosine Phosphorylation Modulates the Activity of TRPV4 in Response to Defined Stimuli

(2008) Tomasz Wegierski et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Clathrin is a key regulator of basolateral polarity

(2008) Sylvie Deborde et al.   NATURE

Exiting the Golgi complex

(2008) Maria Antonietta De Matteis et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Mechanotransduction in vascular physiology and atherogenesis

(2008) Cornelia Hahn et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY