Acyl-CoA synthetase 6 enriches the neuroprotective omega-3 fatty acid DHA in the brain

Increased brain docosahexaenoic acid has no effect on the resolution of neuroinflammation following intracerebroventricular lipopolysaccharide injection

(2018) Marc-Olivier Trépanier et al.   NEUROCHEMISTRY INTERNATIONAL

Treating inflammation and infection in the 21st century: new hints from decoding resolution mediators and mechanisms

(2017) Charles N. Serhan   FASEB JOURNAL

Antarctic Krill Oil Diet Protects against Lipopolysaccharide-Induced Oxidative Stress, Neuroinflammation and Cognitive Impairment

(2017) Ji Choi et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Anti-Inflammatory Effects of Omega-3 Fatty Acids in the Brain: Physiological Mechanisms and Relevance to Pharmacology

(2017) Sophie Layé et al.   PHARMACOLOGICAL REVIEWS

Resolvin D1 and E1 promote resolution of inflammation in microglial cells in vitro

(2016) C. Rey et al.   BRAIN BEHAVIOR AND IMMUNITY

N-3 polyunsaturated fatty acids in animal models with neuroinflammation: An update

(2016) Marc-Olivier Trépanier et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

N-Docosahexaenoylethanolamine ameliorates LPS-induced neuroinflammation via cAMP/PKA-dependent signaling

(2016) Taeyeop Park et al.   Journal of Neuroinflammation

Fish Oil Prevents Lipopolysaccharide-Induced Depressive-Like Behavior by Inhibiting Neuroinflammation

(2016) Zhe Shi et al.   MOLECULAR NEUROBIOLOGY

Aging and peripheral lipopolysaccharide can modulate epigenetic regulators and decrease IL-1β promoter DNA methylation in microglia

(2016) Stephanie M. Matt et al.   NEUROBIOLOGY OF AGING

Dietary DHA and health: cognitive function ageing

(2016) Carlos Cardoso et al.   NUTRITION RESEARCH REVIEWS

Modulation of brain PUFA content in different experimental models of mice

(2016) Corinne Joffre et al.   PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS

Evaluation of Models of Parkinson's Disease

(2016) Shail A. Jagmag et al.   Frontiers in Neuroscience

Acyl CoA synthetase 5 (ACSL5) ablation in mice increases energy expenditure and insulin sensitivity and delays fat absorption

(2016) Thomas A. Bowman et al.   Molecular Metabolism

Docosahexaenoic acid prevents paraquat-induced reactive oxygen species production in dopaminergic neurons via enhancement of glutathione homeostasis

(2015) Hyoung Jun Lee et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Sequential activation of microglia and astrocyte cytokine expression precedes increased iba-1 or GFAP immunoreactivity following systemic immune challenge

(2015) Diana M. Norden et al.   GLIA

Fatty Acid-Binding Protein 5 Facilitates the Blood–Brain Barrier Transport of Docosahexaenoic Acid

(2015) Yijun Pan et al.   MOLECULAR PHARMACEUTICS

Metabolic and Tissue-Specific Regulation of Acyl-CoA Metabolism

(2015) Jessica M. Ellis et al.   PLoS One

Plasma non-esterified docosahexaenoic acid is the major pool supplying the brain

(2015) Chuck T. Chen et al.   Scientific Reports

Pro-resolving lipid mediators are leads for resolution physiology

(2014) Charles N. Serhan   NATURE

Mfsd2a is a transporter for the essential omega-3 fatty acid docosahexaenoic acid

(2014) Long N. Nguyen et al.   NATURE

U.S. adults are not meeting recommended levels for fish and omega-3 fatty acid intake: results of an analysis using observational data from NHANES 2003–2008

(2014) Yanni Papanikolaou et al.   Nutrition Journal

Gene expression of fatty acid transport and binding proteins in the blood–brain barrier and the cerebral cortex of the rat: Differences across development and with different DHA brain status

(2014) Hélène Pélerin et al.   PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS

NADPH oxidase and aging drive microglial activation, oxidative stress, and dopaminergic neurodegeneration following systemic LPS administration

(2013) Liya Qin et al.   GLIA

Inflammatory response and oxidative stress in developing rat brain and its consequences on motor behavior following maternal administration of LPS and perinatal anoxia

(2013) Felipe Stigger et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE

Influence of marine n-3 polyunsaturated fatty acids on immune function and a systematic review of their effects on clinical outcomes in rheumatoid arthritis

(2012) Elizabeth A. Miles et al.   BRITISH JOURNAL OF NUTRITION

L-glutamate released from activated microglia downregulates astrocytic L-glutamate transporter expression in neuroinflammation: the ‘collusion’ hypothesis for increased extracellular L-glutamate concentration in neuroinflammation

(2012) Junpei Takaki et al.   Journal of Neuroinflammation

Major Facilitator Superfamily Domain-Containing Protein 2a (MFSD2A) Has Roles in Body Growth, Motor Function, and Lipid Metabolism

(2012) Justin H. Berger et al.   PLoS One

Polyunsaturated fatty acids and their metabolites in the pathobiology of schizophrenia

(2012) Undurti N. Das   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

A quantum theory for the irreplaceable role of docosahexaenoic acid in neural cell signalling throughout evolution

(2012) Michael A. Crawford et al.   PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS

Mouse Cardiac Acyl Coenzyme A Synthetase 1 Deficiency Impairs Fatty Acid Oxidation and Induces Cardiac Hypertrophy

(2011) J. M. Ellis et al.   MOLECULAR AND CELLULAR BIOLOGY

Identification of Novel Schizophrenia Loci by Homozygosity Mapping Using DNA Microarray Analysis

(2011) Naohiro Kurotaki et al.   PLoS One

Adipose Acyl-CoA Synthetase-1 Directs Fatty Acids toward β-Oxidation and Is Required for Cold Thermogenesis

(2010) Jessica M. Ellis et al.   Cell Metabolism

Acyl-coenzyme A synthetases in metabolic control

(2010) Jessica M Ellis et al.   CURRENT OPINION IN LIPIDOLOGY

Fatty Acids Modulate Toll-like Receptor 4 Activation through Regulation of Receptor Dimerization and Recruitment into Lipid Rafts in a Reactive Oxygen Species-dependent Manner

(2009) Scott W. Wong et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Omega-3 fatty acids: a comprehensive review of their role in health and disease

(2009) B M Yashodhara et al.   POSTGRADUATE MEDICAL JOURNAL

Docosahexaenoic Acid and the Aging Brain

(2008) Walter J. Lukiw et al.   JOURNAL OF NUTRITION