Bridging the gap: Membrane contact sites in signaling, metabolism, and organelle dynamics

Oxysterol-binding proteins: Functions in cell regulation beyond lipid metabolism

(2013) Marion Weber-Boyvat et al.   BIOCHEMICAL PHARMACOLOGY

The endoplasmic reticulum–mitochondria connection: One touch, multiple functions

(2013) Saverio Marchi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

MAM (mitochondria-associated membranes) in mammalian cells: Lipids and beyond

(2013) Jean E. Vance   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

The endoplasmic reticulum and junctional membrane communication during calcium signaling

(2013) Andy K.M. Lam et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Organization and function of membrane contact sites

(2013) Sebastian C.J. Helle et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

A Four-Step Cycle Driven by PI(4)P Hydrolysis Directs Sterol/PI(4)P Exchange by the ER-Golgi Tether OSBP

(2013) Bruno Mesmin et al.   CELL

PI(4,5)P2-Dependent and Ca2+-Regulated ER-PM Interactions Mediated by the Extended Synaptotagmins

(2013) Francesca Giordano et al.   CELL

ER–PM connections: sites of information transfer and inter-organelle communication

(2013) Christopher J Stefan et al.   CURRENT OPINION IN CELL BIOLOGY

An ER-peroxisome tether exerts peroxisome population control in yeast

(2013) Barbara Knoblach et al.   EMBO JOURNAL

Plasma membrane—endoplasmic reticulum contact sites regulate phosphatidylcholine synthesis

(2013) Shabnam Tavassoli et al.   EMBO REPORTS

An Assembly of Proteins and Lipid Domains Regulates Transport of Phosphatidylserine to Phosphatidylserine Decarboxylase 2 inSaccharomyces cerevisiae

(2013) Wayne R. Riekhof et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mcp1 and Mcp2, two novel proteins involved in mitochondrial lipid homeostasis

(2013) T. Tan et al.   JOURNAL OF CELL SCIENCE

STARD3 or STARD3NL and VAP form a novel molecular tether between late endosomes and the ER

(2013) F. Alpy et al.   JOURNAL OF CELL SCIENCE

The yeast cell cortical protein Num1 integrates mitochondrial dynamics into cellular architecture

(2013) T. Klecker et al.   JOURNAL OF CELL SCIENCE

Interactions between sarco-endoplasmic reticulum and mitochondria in cardiac and skeletal muscle - pivotal roles in Ca2+ and reactive oxygen species signaling

(2013) V. Eisner et al.   JOURNAL OF CELL SCIENCE

Interactome map uncovers phosphatidylserine transport by oxysterol-binding proteins

(2013) Kenji Maeda et al.   NATURE

Transorganellar complementation redefines the biochemical continuity of endoplasmic reticulum and chloroplasts

(2013) P. Mehrshahi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Endoplasmic reticulum-associated mitochondria-cortex tether functions in the distribution and inheritance of mitochondria

(2013) L. L. Lackner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

mTOR complex 2-Akt signaling at mitochondria-associated endoplasmic reticulum membranes (MAM) regulates mitochondrial physiology

(2013) C. Betz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lipids of mitochondria

(2013) Susanne E. Horvath et al.   PROGRESS IN LIPID RESEARCH

Impaired  -TTP-PIPs Interaction Underlies Familial Vitamin E Deficiency

(2013) N. Kono et al.   SCIENCE

An Actin-Dependent Step in Mitochondrial Fission Mediated by the ER-Associated Formin INF2

(2013) F. Korobova et al.   SCIENCE

Structure of Osh3 Reveals a Conserved Mode of Phosphoinositide Binding in Oxysterol-Binding Proteins

(2013) Junsen Tong et al.   STRUCTURE

Cell cycle regulation of Golgi membrane dynamics

(2013) Danming Tang et al.   TRENDS IN CELL BIOLOGY

Endoplasmic Reticulum Structure and Interconnections with Other Organelles

(2013) A. R. English et al.   Cold Spring Harbor Perspectives in Biology

Feedback Regulation of Receptor-Induced Ca2+ Signaling Mediated by E-Syt1 and Nir2 at Endoplasmic Reticulum-Plasma Membrane Junctions

(2013) Chi-Lun Chang et al.   Cell Reports

CDIP1-BAP31 Complex Transduces Apoptotic Signals from Endoplasmic Reticulum to Mitochondria under Endoplasmic Reticulum Stress

(2013) Takushi Namba et al.   Cell Reports

ER-associated mitochondrial division links the distribution of mitochondria and mitochondrial DNA in yeast

(2013) Andrew Murley et al.   eLife

Chloroplast lipid synthesis and lipid trafficking through ER–plastid membrane contact sites

(2012) Zhen Wang et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Where the endoplasmic reticulum and the mitochondrion tie the knot: The mitochondria-associated membrane (MAM)

(2012) Arun Raturi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Mitofilin complexes: conserved organizers of mitochondrial membrane architecture

(2012) Ralf M. Zerbes et al.   BIOLOGICAL CHEMISTRY

STIM1 Juxtaposes ER to Phagosomes, Generating Ca2+ Hotspots that Boost Phagocytosis

(2012) Paula Nunes et al.   CURRENT BIOLOGY

ER-to-Plasma Membrane Tethering Proteins Regulate Cell Signaling and ER Morphology

(2012) Andrew G. Manford et al.   DEVELOPMENTAL CELL

Role for Two Conserved Intermembrane Space Proteins, Ups1p and Up2p, in Intra-mitochondrial Phospholipid Trafficking

(2012) Yasushi Tamura et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The FATP1–DGAT2 complex facilitates lipid droplet expansion at the ER–lipid droplet interface

(2012) Ningyi Xu et al.   JOURNAL OF CELL BIOLOGY

ER-shaping proteins facilitate lipid exchange between the ER and mitochondria in S. cerevisiae

(2012) C. Voss et al.   JOURNAL OF CELL SCIENCE

A conserved membrane-binding domain targets proteins to organelle contact sites

(2012) A. Toulmay et al.   JOURNAL OF CELL SCIENCE

Structural basis of transfer between lipoproteins by cholesteryl ester transfer protein

(2012) Lei Zhang et al.   Nature Chemical Biology

Regulation of Signaling at Regions of Cell-Cell Contact by Endoplasmic Reticulum-Bound Protein-Tyrosine Phosphatase 1B

(2012) Fawaz G. Haj et al.   PLoS One

Intramitochondrial Transport of Phosphatidic Acid in Yeast by a Lipid Transfer Protein

(2012) M. Connerth et al.   SCIENCE

Gem1 and ERMES Do Not Directly Affect Phosphatidylserine Transport from ER to Mitochondria or Mitochondrial Inheritance

(2012) Tammy T. Nguyen et al.   TRAFFIC

Role of MINOS in mitochondrial membrane architecture and biogenesis

(2012) Martin van der Laan et al.   TRENDS IN CELL BIOLOGY

Molecular mechanisms of endolysosomal Ca2+signalling in health and disease

(2011) Anthony J. Morgan et al.   BIOCHEMICAL JOURNAL

The β1a Subunit of the Skeletal DHPR Binds to Skeletal RyR1 and Activates the Channel via Its 35-Residue C-Terminal Tail

(2011) Robyn T. Rebbeck et al.   BIOPHYSICAL JOURNAL

Osh Proteins Regulate Phosphoinositide Metabolism at ER-Plasma Membrane Contact Sites

(2011) Christopher J. Stefan et al.   CELL

Calcium entry-calcium refilling (CECR) coupling between store-operated Ca2+ entry and sarco/endoplasmic reticulum Ca2+-ATPase

(2011) Isabel M. Manjarrés et al.   CELL CALCIUM

Role for cER and Mmr1p in Anchorage of Mitochondria at Sites of Polarized Surface Growth in Budding Yeast

(2011) Theresa C. Swayne et al.   CURRENT BIOLOGY

Dual Role of Mitofilin in Mitochondrial Membrane Organization and Protein Biogenesis

(2011) Karina von der Malsburg et al.   DEVELOPMENTAL CELL

The mitochondrial contact site complex, a determinant of mitochondrial architecture

(2011) Max Harner et al.   EMBO JOURNAL

STIM1 couples to ORAI1 via an intramolecular transition into an extended conformation

(2011) Martin Muik et al.   EMBO JOURNAL

VAPB interacts with the mitochondrial protein PTPIP51 to regulate calcium homeostasis

(2011) Kurt J. De Vos et al.   HUMAN MOLECULAR GENETICS

A mitochondrial-focused genetic interaction map reveals a scaffold-like complex required for inner membrane organization in mitochondria

(2011) Suzanne Hoppins et al.   JOURNAL OF CELL BIOLOGY

A role for oxysterol-binding protein–related protein 5 in endosomal cholesterol trafficking

(2011) Ximing Du et al.   JOURNAL OF CELL BIOLOGY

Osh4p exchanges sterols for phosphatidylinositol 4-phosphate between lipid bilayers

(2011) Maud de Saint-Jean et al.   JOURNAL OF CELL BIOLOGY

Making heads or tails of phospholipids in mitochondria

(2011) Christof Osman et al.   JOURNAL OF CELL BIOLOGY

ER Tubules Mark Sites of Mitochondrial Division

(2011) J. R. Friedman et al.   SCIENCE

Physiological roles of NAADP-mediated Ca2+ signaling

(2011) Antony Galione et al.   Science China-Life Sciences

Chlamydia trachomatis Co-opts GBF1 and CERT to Acquire Host Sphingomyelin for Distinct Roles during Intracellular Development

(2011) Cherilyn A. Elwell et al.   PLoS Pathogens

The Lipid Transfer Protein CERT Interacts with the Chlamydia Inclusion Protein IncD and Participates to ER-Chlamydia Inclusion Membrane Contact Sites

(2011) Isabelle Derré et al.   PLoS Pathogens

Homology of SMP domains to the TULIP superfamily of lipid-binding proteins provides a structural basis for lipid exchange between ER and mitochondria

(2010) Klaus O. Kopec et al.   BIOINFORMATICS

Fis1 and Bap31 bridge the mitochondria-ER interface to establish a platform for apoptosis induction

(2010) Ryota Iwasawa et al.   EMBO JOURNAL

GRASP55 and GRASP65 play complementary and essential roles in Golgi cisternal stacking

(2010) Yi Xiang et al.   JOURNAL OF CELL BIOLOGY

PTP1B regulates Eph receptor function and trafficking

(2010) Eva Nievergall et al.   JOURNAL OF CELL BIOLOGY

Looking for answers to EC coupling’s persistent questions: Figure 1.

(2010) Kurt G. Beam et al.   JOURNAL OF GENERAL PHYSIOLOGY

Imaging Interorganelle Contacts and Local Calcium Dynamics at the ER-Mitochondrial Interface

(2010) György Csordás et al.   MOLECULAR CELL

Non-vesicular lipid transport by lipid-transfer proteins and beyond

(2010) Sima Lev   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Intracellular trafficking of ceramide by ceramide transfer protein

(2010) Kentaro HANADA   PROCEEDINGS OF THE JAPAN ACADEMY SERIES B-PHYSICAL AND BIOLOGICAL SCIENCES

A minimal regulatory domain in the C terminus of STIM1 binds to and activates ORAI1 CRAC channels

(2009) Takumi Kawasaki et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

STIM1 Clusters and Activates CRAC Channels via Direct Binding of a Cytosolic Domain to Orai1

(2009) Chan Young Park et al.   CELL

Visualizing the store-operated channel complex assembly in real time: Identification of SERCA2 as a new member

(2009) Alicia Sampieri et al.   CELL CALCIUM

Ribosome-free Terminals of Rough ER Allow Formation of STIM1 Puncta and Segregation of STIM1 from IP3 Receptors

(2009) Gyorgy Lur et al.   CURRENT BIOLOGY

A Cytosolic Homomerization and a Modulatory Domain within STIM1 C Terminus Determine Coupling to ORAI1 Channels

(2009) Martin Muik et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cholesterol sensor ORP1L contacts the ER protein VAP to control Rab7–RILP–p150Gluedand late endosome positioning

(2009) Nuno Rocha et al.   JOURNAL OF CELL BIOLOGY

Prohibitins and the functional compartmentalization of mitochondrial membranes

(2009) C. Osman et al.   JOURNAL OF CELL SCIENCE

STIM protein coupling in the activation of Orai channels

(2009) Y. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

STIM1-induced precortical and cortical subdomains of the endoplasmic reticulum

(2009) L. Orci et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An ER-Mitochondria Tethering Complex Revealed by a Synthetic Biology Screen

(2009) Benoît Kornmann et al.   SCIENCE

Binding of Plasma Membrane Lipids Recruits the Yeast Integral Membrane Protein Ist2 to the Cortical ER

(2009) Marcel André Fischer et al.   TRAFFIC

Structural and Mechanistic Insights into STIM1-Mediated Initiation of Store-Operated Calcium Entry

(2008) Peter B. Stathopulos et al.   CELL

Lysosomes co-localize with ryanodine receptor subtype 3 to form a trigger zone for calcium signalling by NAADP in rat pulmonary arterial smooth muscle

(2008) Nicholas P. Kinnear et al.   CELL CALCIUM

Lipid-transfer proteins in biosynthetic pathways

(2008) Giovanni D’Angelo et al.   CURRENT OPINION IN CELL BIOLOGY

Coordinated Lipid Transfer between the Endoplasmic Reticulum and the Golgi Complex Requires the VAP Proteins and Is Essential for Golgi-mediated Transport

(2008) Diego Peretti et al.   MOLECULAR BIOLOGY OF THE CELL

Functional Anatomy of Phospholipid Binding and Regulation of Phosphoinositide Homeostasis by Proteins of the Sec14 Superfamily

(2008) Gabriel Schaaf et al.   MOLECULAR CELL

Mitofusin 2 tethers endoplasmic reticulum to mitochondria

(2008) Olga Martins de Brito et al.   NATURE