Taurine improves low-level inorganic arsenic-induced insulin resistance by activating PPARγ-mTORC2 signalling and inhibiting hepatic autophagy

Chlorogenic acid alleviates autophagy and insulin resistance by suppressing JNK pathway in a rat model of nonalcoholic fatty liver disease

(2018) Hua Yan et al.   JOURNAL OF BIOSCIENCES

Differentially expressed genes in PPARγ-deficient MSCs

(2018) Yun Su et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Association between consumption of private well water contaminated by low levels of arsenic and dysglycemia in a rural region of Quebec, Canada

(2017) Éric Lampron-Goulet et al.   ENVIRONMENTAL RESEARCH

Sestrin 2 induces autophagy and attenuates insulin resistance by regulating AMPK signaling in C2C12 myotubes

(2017) Huige Li et al.   EXPERIMENTAL CELL RESEARCH

Prophylactic role of taurine and its derivatives against diabetes mellitus and its related complications

(2017) Poulami Sarkar et al.   FOOD AND CHEMICAL TOXICOLOGY

Progranulin causes adipose insulin resistance via increased autophagy resulting from activated oxidative stress and endoplasmic reticulum stress

(2017) Qinyue Guo et al.   Lipids in Health and Disease

The Role of Mammalian Target of Rapamycin (mTOR) in Insulin Signaling

(2017) Mee-Sup Yoon   Nutrients

The Association of Arsenic Exposure and Metabolism With Type 1 and Type 2 Diabetes in Youth: The SEARCH Case-Control Study

(2016) Maria Grau-Pérez et al.   DIABETES CARE

Arsenic exposure is associated with diminished insulin sensitivity in non-diabetic Amish adults

(2016) Sung Kyun Park et al.   DIABETES-METABOLISM RESEARCH AND REVIEWS

Depression mediates impaired glucose tolerance and cognitive dysfunction: A neuromodulatory role of rosiglitazone

(2016) Sita Sharan Patel et al.   HORMONES AND BEHAVIOR

The pathogenesis of insulin resistance: integrating signaling pathways and substrate flux

(2016) Varman T. Samuel et al.   JOURNAL OF CLINICAL INVESTIGATION

Inhibition of JNK suppresses autophagy and attenuates insulin resistance in a rat model of nonalcoholic fatty liver disease

(2016) Hua Yan et al.   Molecular Medicine Reports

Taurine protects against As2O3-induced autophagy in livers of rat offsprings through PPARγ pathway

(2016) Jie Bai et al.   Scientific Reports

Impact of taurine depletion on glucose control and insulin secretion in mice

(2015) Takashi Ito et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

LC3- and p62-based biochemical methods for the analysis of autophagy progression in mammalian cells

(2015) Peidu Jiang et al.   METHODS

Dihydromyricetin improves skeletal muscle insulin resistance by inducing autophagy via the AMPK signaling pathway

(2015) Linying Shi et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Arsenic Induces Insulin Resistance in Mouse Adipocytes and Myotubes Via Oxidative Stress-Regulated Mitochondrial Sirt3-FOXO3a Signaling Pathway

(2015) Sasidharan Padmaja Divya et al.   TOXICOLOGICAL SCIENCES

Natural product agonists of peroxisome proliferator-activated receptor gamma (PPARγ): a review

(2014) Limei Wang et al.   BIOCHEMICAL PHARMACOLOGY

Improving Type 2 Diabetes Through a Distinct Adrenergic Signaling Pathway Involving mTORC2 That Mediates Glucose Uptake in Skeletal Muscle

(2014) M. Sato et al.   DIABETES

Long-Term Exposure to Low-Level Arsenic in Drinking Water and Diabetes Incidence: A Prospective Study of the Diet, Cancer and Health Cohort

(2014) Elvira Vaclavik Bräuner et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

The role of hepatic lipids in hepatic insulin resistance and type 2 diabetes

(2014) Rachel J. Perry et al.   NATURE

The SLC2 (GLUT) family of membrane transporters

(2013) Mike Mueckler et al.   MOLECULAR ASPECTS OF MEDICINE

PPARγ signaling and metabolism: the good, the bad and the future

(2013) Maryam Ahmadian et al.   NATURE MEDICINE

Arsenic Exposure and Calpain-10 Polymorphisms Impair the Function of Pancreatic Beta-Cells in Humans: A Pilot Study of Risk Factors for T2DM

(2013) Andrea Díaz-Villaseñor et al.   PLoS One

Submaximal PPARγ activation and endothelial dysfunction: new perspectives for the management of cardiovascular disorders

(2012) Pitchai Balakumar et al.   BRITISH JOURNAL OF PHARMACOLOGY

Hepatic mTORC2 Activates Glycolysis and Lipogenesis through Akt, Glucokinase, and SREBP1c

(2012) Asami Hagiwara et al.   Cell Metabolism

Evaluation of the Association between Arsenic and Diabetes: A National Toxicology Program Workshop Review

(2012) Elizabeth A. Maull et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Taurine ameliorates hyperglycemia and dyslipidemia by reducing insulin resistance and leptin level in Otsuka Long-Evans Tokushima fatty (OLETF) rats with long-term diabetes

(2012) Kyoung Soo Kim et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

Thiazolidinedione safety

(2012) Jacqueline Kung et al.   Expert Opinion On Drug Safety

Dietary Combination of Fish Oil and Taurine Decreases Fat Accumulation and Ameliorates Blood Glucose Levels in Type 2 Diabetic/Obese KK-Ay Mice

(2012) Nana Mikami et al.   JOURNAL OF FOOD SCIENCE

Major involvement of mTOR in the PPARγ-induced stimulation of adipose tissue lipid uptake and fat accretion

(2012) Pierre-Gilles Blanchard et al.   JOURNAL OF LIPID RESEARCH

Rapamycin-Induced Insulin Resistance Is Mediated by mTORC2 Loss and Uncoupled from Longevity

(2012) D. W. Lamming et al.   SCIENCE

PPARγ Agonist Improves Neuronal Insulin Receptor Function in Hippocampus and Brain Mitochondria Function in Rats with Insulin Resistance Induced by Long Term High-Fat Diets

(2011) Noppamas Pipatpiboon et al.   ENDOCRINOLOGY

Taurine exerts hypoglycemic effect in alloxan-induced diabetic rats, improves insulin-mediated glucose transport signaling pathway in heart and ameliorates cardiac oxidative stress and apoptosis

(2011) Joydeep Das et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Global estimates of the prevalence of diabetes for 2010 and 2030

(2009) J.E. Shaw et al.   DIABETES RESEARCH AND CLINICAL PRACTICE

Insights into PPARγ from structures with endogenous and covalently bound ligands

(2008) Kendall W Nettles   NATURE STRUCTURAL & MOLECULAR BIOLOGY