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Title
Werner Syndrome Protein and DNA Replication
Authors
Keywords
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Journal
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Volume 19, Issue 11, Pages 3442
Publisher
MDPI AG
Online
2018-11-05
DOI
10.3390/ijms19113442
References
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Related references
Note: Only part of the references are listed.- Werner syndrome ( WRN ) gene variants and their association with altered function and age-associated diseases
- (2018) Michel Lebel et al. AGEING RESEARCH REVIEWS
- Repair of DNA double-strand breaks by mammalian alternative end-joining pathways
- (2018) Annahita Sallmyr et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- A Cell-Intrinsic Interferon-like Response Links Replication Stress to Cellular Aging Caused by Progerin
- (2018) Ray Kreienkamp et al. Cell Reports
- Recent Trends in WRN Gene Mutation Patterns in Individuals with Werner Syndrome
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- cGAS surveillance of micronuclei links genome instability to innate immunity
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- Mitotic progression following DNA damage enables pattern recognition within micronuclei
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- Cytoplasmic chromatin triggers inflammation in senescence and cancer
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- Innate immune sensing of cytosolic chromatin fragments through cGAS promotes senescence
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- RAD51 interconnects between DNA replication, DNA repair and immunity
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- cGAS is essential for cellular senescence
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- WRNMutation Update: Mutation Spectrum, Patient Registries, and Translational Prospects
- (2016) Koutaro Yokote et al. HUMAN MUTATION
- Class I Histone Deacetylase HDAC1 and WRN RECQ Helicase Contribute Additively to Protect Replication Forks upon Hydroxyurea-induced Arrest
- (2016) Keffy Kehrli et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- DNA double-strand-break repair in higher eukaryotes and its role in genomic instability and cancer: Cell cycle and proliferation-dependent regulation
- (2016) Emil Mladenov et al. SEMINARS IN CANCER BIOLOGY
- Repair Pathway Choices and Consequences at the Double-Strand Break
- (2016) Raphael Ceccaldi et al. TRENDS IN CELL BIOLOGY
- CDK1 phosphorylates WRN at collapsed replication forks
- (2016) Valentina Palermo et al. Nature Communications
- WRN regulates pathway choice between classical and alternative non-homologous end joining
- (2016) Raghavendra A. Shamanna et al. Nature Communications
- Camptothecin targets WRN protein: mechanism and relevance in clinical breast cancer
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- Serines 440 and 467 in the Werner syndrome protein are phosphorylated by DNA-PK and affects its dynamics in response to DNA double strand breaks
- (2016) Rika Kusumoto-Matsuo et al. Aging-US
- BRCA1 and CtIP promote alternative non-homologous end-joining at uncapped telomeres
- (2015) S. Badie et al. EMBO JOURNAL
- The WRN exonuclease domain protects nascent strands from pathological MRE11/EXO1-dependent degradation
- (2015) Chiara Iannascoli et al. NUCLEIC ACIDS RESEARCH
- The DNA structure and sequence preferences of WRN underlie its function in telomeric recombination events
- (2015) Deanna N. Edwards et al. Nature Communications
- Replication stress induced site-specific phosphorylation targets WRN to the ubiquitin-proteasome pathway
- (2015) Fengtao Su et al. Oncotarget
- Acetylation of Werner syndrome protein (WRN): relationships with DNA damage, DNA replication and DNA metabolic activities
- (2014) Enerlyn Lozada et al. BIOGERONTOLOGY
- Cellular Differences in Protein Synthesis Regulate Tissue Homeostasis
- (2014) Michael Buszczak et al. CELL
- Prognostic and Predictive Values of the Immunoscore in Patients with Rectal Cancer
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- Nonenzymatic Role for WRN in Preserving Nascent DNA Strands after Replication Stress
- (2014) Fengtao Su et al. Cell Reports
- Spectrum and Risk of Neoplasia in Werner Syndrome: A Systematic Review
- (2013) Julia M. Lauper et al. PLoS One
- Perturbed replication induced genome wide or at common fragile sites is differently managed in the absence of WRN
- (2012) I. Murfuni et al. CARCINOGENESIS
- Distinct functions of human RECQ helicases WRN and BLM in replication fork recovery and progression after hydroxyurea-induced stalling
- (2012) Julia M. Sidorova et al. DNA REPAIR
- Aging-associated inflammation in healthy Japanese individuals and patients with Werner syndrome
- (2012) Makoto Goto et al. EXPERIMENTAL GERONTOLOGY
- RECQL5 plays co-operative and complementary roles with WRN syndrome helicase
- (2012) Venkateswarlu Popuri et al. NUCLEIC ACIDS RESEARCH
- The Werner Syndrome Protein Is Distinguished from the Bloom Syndrome Protein by Its Capacity to Tightly Bind Diverse DNA Structures
- (2012) Ashwini Kamath-Loeb et al. PLoS One
- The Werner and Bloom Syndrome Proteins Help Resolve Replication Blockage by Converting (Regressed) Holliday Junctions to Functional Replication Forks
- (2011) Amrita Machwe et al. BIOCHEMISTRY
- DNA repair by nonhomologous end joining and homologous recombination during cell cycle in human cells
- (2011) Zhiyong Mao et al. CELL CYCLE
- The Werner syndrome protein affects the expression of genes involved in adipogenesis and inflammation in addition to cell cycle and DNA damage responses
- (2011) Ramachander V.N. Turaga et al. CELL CYCLE
- The DNA repair endonuclease XPG interacts directly and functionally with the WRN helicase defective in Werner syndrome
- (2011) Kelly S. Trego et al. CELL CYCLE
- The RAD9–RAD1–HUS1 (9.1.1) complex interacts with WRN and is crucial to regulate its response to replication fork stalling
- (2011) P Pichierri et al. ONCOGENE
- Inhibition of helicase activity by a small molecule impairs Werner syndrome helicase (WRN) function in the cellular response to DNA damage or replication stress
- (2011) M. Aggarwal et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The RecQ helicase WRN is required for normal replication fork progression after DNA damage or replication fork arrest
- (2010) Julia M. Sidorova et al. CELL CYCLE
- ATR and ATM differently regulate WRN to prevent DSBs at stalled replication forks and promote replication fork recovery
- (2010) Francesca Ammazzalorso et al. EMBO JOURNAL
- The function of classical and alternative non-homologous end-joining pathways in the fusion of dysfunctional telomeres
- (2010) Rekha Rai et al. EMBO JOURNAL
- WRN mutations in Werner syndrome patients: genomic rearrangements, unusual intronic mutations and ethnic-specific alterations
- (2010) Katrin Friedrich et al. HUMAN GENETICS
- Identification of a Coiled Coil in Werner Syndrome Protein That Facilitates Multimerization and Promotes Exonuclease Processivity
- (2010) J. Jefferson P. Perry et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Molecular Cooperation between the Werner Syndrome Protein and Replication Protein A in Relation to Replication Fork Blockage
- (2010) Amrita Machwe et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- WRN participates in translesion synthesis pathway through interaction with NBS1
- (2010) Junya Kobayashi et al. MECHANISMS OF AGEING AND DEVELOPMENT
- CtIP promotes microhomology-mediated alternative end joining during class-switch recombination
- (2010) Mieun Lee-Theilen et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Acetylation of WRN Protein Regulates Its Stability by Inhibiting Ubiquitination
- (2010) Kai Li et al. PLoS One
- Vitamin C restores healthy aging in a mouse model for Werner syndrome
- (2009) Laurent Massip et al. FASEB JOURNAL
- Roles of the Werner syndrome RecQ helicase in DNA replication
- (2008) Julia M. Sidorova DNA REPAIR
- The Werner Syndrome Protein Binds Replication Fork and Holliday Junction DNAs as an Oligomer
- (2008) Sarah A. Compton et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Replication fork stalling in WRN-deficient cells is overcome by prompt activation of a MUS81-dependent pathway
- (2008) Annapaola Franchitto et al. JOURNAL OF CELL BIOLOGY
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