ATR and ATM differently regulate WRN to prevent DSBs at stalled replication forks and promote replication fork recovery

The RecQ helicase WRN is required for normal replication fork progression after DNA damage or replication fork arrest

(2010) Julia M. Sidorova et al.   CELL CYCLE

Hydroxyurea-Stalled Replication Forks Become Progressively Inactivated and Require Two Different RAD51-Mediated Pathways for Restart and Repair

(2010) Eva Petermann et al.   MOLECULAR CELL

ATR/Mec1: coordinating fork stability and repair

(2009) Anna M Friedel et al.   CURRENT OPINION IN CELL BIOLOGY

Roles of the Werner syndrome RecQ helicase in DNA replication

(2008) Julia M. Sidorova   DNA REPAIR

The clinical characteristics of Werner syndrome: molecular and biochemical diagnosis

(2008) Meltem Muftuoglu et al.   HUMAN GENETICS

ATR and H2AX Cooperate in Maintaining Genome Stability under Replication Stress

(2008) Rebecca A. Chanoux et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Werner syndrome helicase activity is essential in maintaining fragile site stability

(2008) Livia Maria Pirzio et al.   JOURNAL OF CELL BIOLOGY

Replication fork stalling in WRN-deficient cells is overcome by prompt activation of a MUS81-dependent pathway

(2008) Annapaola Franchitto et al.   JOURNAL OF CELL BIOLOGY

ATR: an essential regulator of genome integrity

(2008) Karlene A. Cimprich et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

An Oncogene-Induced DNA Damage Model for Cancer Development

(2008) T. D. Halazonetis et al.   SCIENCE

Rising from the RecQ-age: the role of human RecQ helicases in genome maintenance

(2008) V BOHR   TRENDS IN BIOCHEMICAL SCIENCES