Oxygen triggers signal transduction in the DevS (DosS) sensor of Mycobacterium tuberculosis by modulating the quaternary structure

Architecture of the complete oxygen-sensing FixL-FixJ two-component signal transduction system

(2018) Gareth S. A. Wright et al.   Science Signaling

Architecture of the complete oxygen-sensing FixL-FixJ two-component signal transduction system

(2018) Gareth S. A. Wright et al.   Science Signaling

Target DNA stabilizes Mycobacterium tuberculosis DevR/DosR phosphorylation by the full-length oxygen sensors DevS/DosS and DosT

(2017) Eduardo H. S. Sousa et al.   FEBS Journal

Coordination and redox state–dependent structural changes of the heme-based oxygen sensorAfGcHK associated with intraprotein signal transduction

(2017) Martin Stranava et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Insights into signal transduction by a hybrid FixL: Denaturation study of on and off states of a multi-domain oxygen sensor

(2017) Wellinson G. Guimarães et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Drug discovery targeting heme-based sensors and their coupled activities

(2017) Eduardo Henrique Silva Sousa et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Oligomeric states in sodium ion-dependent regulation of cyanobacterial histidine kinase-2

(2017) Iskander M. Ibrahim et al.   PROTOPLASMA

An Oxygen-Sensing Two-Component System in the Burkholderia cepacia Complex Regulates Biofilm, Intracellular Invasion, and Pathogenicity

(2017) Matthew M. Schaefers et al.   PLoS Pathogens

Crystal structures of the CO and NO Bound DosS GAF-A domain and implications for DosS signaling in Mycobacterium tuberculosis

(2016) Yarrow Madrona et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Oxygen and Bis(3′,5′)-cyclic Dimeric Guanosine Monophosphate Binding Control Oligomerization State Equilibria of Diguanylate Cyclase-Containing Globin Coupled Sensors

(2016) Justin L. Burns et al.   BIOCHEMISTRY

Structural characterization of the heme-based oxygen sensor,AfGcHK, its interactions with the cognate response regulator, and their combined mechanism of action in a bacterial two-component signaling system

(2016) Martin Stranava et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

An O2-sensing stressosome from a Gram-negative bacterium

(2016) Xin Jia et al.   Nature Communications

Virulence Factor SenX3 Is the Oxygen-Controlled Replication Switch of Mycobacterium tuberculosis

(2015) Nisha Singh et al.   ANTIOXIDANTS & REDOX SIGNALING

Kinetic Analysis of a Globin-Coupled Histidine Kinase, AfGcHK: Effects of the Heme Iron Complex, Response Regulator, and Metal Cations on Autophosphorylation Activity

(2015) Veronika Fojtikova et al.   BIOCHEMISTRY

Gaseous O2, NO, and CO in Signal Transduction: Structure and Function Relationships of Heme-Based Gas Sensors and Heme-Redox Sensors

(2015) Toru Shimizu et al.   CHEMICAL REVIEWS

A bug’s life in the granuloma

(2015) Constance J. Martin et al.   Seminars in Immunopathology

Biomolecule-compatible chemical bond-formation and bond-cleavage reactions induced by visible light

(2015) Chenchen Hu et al.   TETRAHEDRON LETTERS

Structural analysis of an oxygen-regulated diguanylate cyclase

(2015) Miroslaw Tarnawski et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Latent Tuberculosis Infection: Myths, Models, and Molecular Mechanisms

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Oligomeric state affects oxygen dissociation and diguanylate cyclase activity of globin coupled sensors

(2014) Justin L. Burns et al.   Molecular BioSystems

Nitric Oxide-Induced Conformational Changes in Soluble Guanylate Cyclase

(2014) Eric S. Underbakke et al.   STRUCTURE

Molecular Model of a Soluble Guanylyl Cyclase Fragment Determined by Small-Angle X-ray Scattering and Chemical Cross-Linking

(2013) Bradley G. Fritz et al.   BIOCHEMISTRY

Signal Transduction and Phosphoryl Transfer by a FixL Hybrid Kinase with Low Oxygen Affinity: Importance of the Vicinal PAS Domain and Receiver Aspartate

(2013) Eduardo H. S. Sousa et al.   BIOCHEMISTRY

FixL-like sensor FlbS ofBrucella abortusbinds haem and is necessary for survival within eukaryotic cells

(2013) Mara S. Roset et al.   FEBS LETTERS

Activation of ATP Binding for the Autophosphorylation of DosS, aMycobacterium tuberculosisHistidine Kinase Lacking an ATP Lid Motif

(2013) Ha Yeon Cho et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Heme-based Redox Sensor in the Methanogenic ArchaeonMethanosarcina acetivorans

(2013) Bastian Molitor et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Novel FixL homologues inChlamydomonas reinhardtiibind heme and O2

(2012) U.M. Narayana Murthy et al.   FEBS LETTERS

Protein-protein interactions between histidine kinases and response regulators of Mycobacterium tuberculosis H37Rv

(2012) Ha-Na Lee et al.   JOURNAL OF MICROBIOLOGY

The NtrY/X two-component system of Brucella spp. acts as a redox sensor and regulates the expression of nitrogen respiration enzymes

(2012) Mariela del Carmen Carrica et al.   MOLECULAR MICROBIOLOGY

Tuberculosis, Drug Resistance, and the History of Modern Medicine

(2012) Salmaan Keshavjee et al.   NEW ENGLAND JOURNAL OF MEDICINE

Appropriate DevR (DosR)-Mediated Signaling Determines Transcriptional Response, Hypoxic Viability and Virulence of Mycobacterium tuberculosis

(2012) Shyamasree De Majumdar et al.   PLoS One

Ultrafast Ligand Dynamics in the Heme-Based GAF Sensor Domains of the Histidine Kinases DosS and DosT from Mycobacterium tuberculosis

(2011) Marten H. Vos et al.   BIOCHEMISTRY

Cyclic di-GMP Activation of Polynucleotide Phosphorylase Signal-Dependent RNA Processing

(2011) Jason R. Tuckerman et al.   JOURNAL OF MOLECULAR BIOLOGY

Nitric Oxide Dioxygenation Reaction in DevS and the Initial Response to Nitric Oxide inMycobacterium tuberculosis

(2010) Erik T. Yukl et al.   BIOCHEMISTRY

Oligomeric Sensor Kinase DcuS in the Membrane of Escherichia coli and in Proteoliposomes: Chemical Cross-linking and FRET Spectroscopy

(2010) P. D. Scheu et al.   JOURNAL OF BACTERIOLOGY

DevS Oxy Complex Stability Identifies This Heme Protein as a Gas Sensor inMycobacterium tuberculosisDormancy

(2009) Alexandra Ioanoviciu et al.   BIOCHEMISTRY

An Oxygen-Sensing Diguanylate Cyclase and Phosphodiesterase Couple for c-di-GMP Control

(2009) Jason R. Tuckerman et al.   BIOCHEMISTRY

Molecular oxygen regulates the enzymatic activity of a heme-containing diguanylate cyclase (HemDGC) for the synthesis of cyclic di-GMP

(2009) Hitomi Sawai et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Unique Roles of DosT and DosS in DosR Regulon Induction and Mycobacterium tuberculosis Dormancy

(2009) R. W. Honaker et al.   INFECTION AND IMMUNITY

Structural Insight into the Heme-based Redox Sensing by DosS fromMycobacterium tuberculosis

(2009) Ha Yeon Cho et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Heme Ligand Binding Properties and Intradimer Interactions in the Full-length Sensor Protein Dos from Escherichia coli and Its Isolated Heme Domain

(2009) Christophe Lechauve et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Distal Tyrosine Residue Is Required for Ligand Discrimination in DevS fromMycobacterium tuberculosis†

(2008) Erik T. Yukl et al.   BIOCHEMISTRY

2.3 Å X-ray Structure of the Heme-Bound GAF Domain of Sensory Histidine Kinase DosT ofMycobacterium tuberculosis†‡

(2008) Larissa M. Podust et al.   BIOCHEMISTRY

Phosphorylation-Independent Regulation of the Diguanylate Cyclase WspR

(2008) Nabanita De et al.   PLOS BIOLOGY