Matricellular proteins: priming the tumour microenvironment for cancer development and metastasis

Enzymatic Targeting of the Stroma Ablates Physical Barriers to Treatment of Pancreatic Ductal Adenocarcinoma

(2012) Paolo P. Provenzano et al.   CANCER CELL

The extracellular matrix: A dynamic niche in cancer progression

(2012) Pengfei Lu et al.   JOURNAL OF CELL BIOLOGY

Losartan Slows Pancreatic Tumor Progression and Extends Survival of SPARC-Null Mice by Abrogating Aberrant TGFβ Activation

(2012) Shanna A. Arnold et al.   PLoS One

Causes, consequences, and remedies for growth-induced solid stress in murine and human tumors

(2012) T. Stylianopoulos et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Both osteopontin-c and osteopontin-b splicing isoforms exert pro-tumorigenic roles in prostate cancer cells

(2012) Tatiana M. Tilli et al.   PROSTATE

Cancer Invasion and the Microenvironment: Plasticity and Reciprocity

(2011) Peter Friedl et al.   CELL

Emerging functions of matricellular proteins

(2011) David D. Roberts   CELLULAR AND MOLECULAR LIFE SCIENCES

Remodeling and homeostasis of the extracellular matrix: implications for fibrotic diseases and cancer

(2011) T. R. Cox et al.   Disease Models & Mechanisms

Proteomic Profiling of Human Melanoma Metastatic Cell Line Secretomes

(2011) Micaela Rocco et al.   JOURNAL OF PROTEOME RESEARCH

Osteopontin-c Splicing Isoform Contributes to Ovarian Cancer Progression

(2011) T. M. Tilli et al.   MOLECULAR CANCER RESEARCH

Neutralizing Monoclonal Antibody to Periostin Inhibits Ovarian Tumor Growth and Metastasis

(2011) M. Zhu et al.   MOLECULAR CANCER THERAPEUTICS

Interactions between cancer stem cells and their niche govern metastatic colonization

(2011) Ilaria Malanchi et al.   NATURE

Breast cancer cells produce tenascin C as a metastatic niche component to colonize the lungs

(2011) Thordur Oskarsson et al.   NATURE MEDICINE

Normalization of the Vasculature for Treatment of Cancer and Other Diseases

(2011) Shom Goel et al.   PHYSIOLOGICAL REVIEWS

VEGF-A and Tenascin-C produced by S100A4+ stromal cells are important for metastatic colonization

(2011) J. T. O'Connell et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Perspective on Cancer Cell Metastasis

(2011) C. L. Chaffer et al.   SCIENCE

Matricellular proteins: from homeostasis to inflammation, cancer, and metastasis

(2010) Claudia Chiodoni et al.   CANCER AND METASTASIS REVIEWS

Periostin, a Cell Adhesion Molecule, Facilitates Invasion in the Tumor Microenvironment and Annotates a Novel Tumor-Invasive Signature in Esophageal Cancer

(2010) C. Z. Michaylira et al.   CANCER RESEARCH

Matrix Metalloproteinases: Regulators of the Tumor Microenvironment

(2010) Kai Kessenbrock et al.   CELL

Osteopontin: An Effector and an Effect of Tumor Metastasis

(2010) L. Shevde et al.   CURRENT MOLECULAR MEDICINE

Interaction between Periostin and BMP-1 Promotes Proteolytic Activation of Lysyl Oxidase

(2010) Takumi Maruhashi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Tenascin-C Is a Novel RBPJ -Induced Target Gene for Notch Signaling in Gliomas

(2009) B. Sivasankaran et al.   CANCER RESEARCH

Matrix Crosslinking Forces Tumor Progression by Enhancing Integrin Signaling

(2009) Kandice R. Levental et al.   CELL

Incorporation of Tenascin-C into the Extracellular Matrix by Periostin Underlies an Extracellular Meshwork Architecture

(2009) Isao Kii et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Osteopontin promotes fibrosis in dystrophic mouse muscle by modulating immune cell subsets and intramuscular TGF-β

(2009) Sylvia A. Vetrone et al.   JOURNAL OF CLINICAL INVESTIGATION

The basics of epithelial-mesenchymal transition

(2009) Raghu Kalluri et al.   JOURNAL OF CLINICAL INVESTIGATION

Expression Patterns of Aurora Kinase B, Heat Shock Protein 47, and Periostin in Esophageal Squamous Cell Carcinoma

(2009) Yong-Jae Kwon et al.   ONCOLOGY RESEARCH

Deficiency of tenascin-C delays articular cartilage repair in mice

(2009) N. Okamura et al.   OSTEOARTHRITIS AND CARTILAGE

Inhibition of Hedgehog Signaling Enhances Delivery of Chemotherapy in a Mouse Model of Pancreatic Cancer

(2009) K. P. Olive et al.   SCIENCE

Modulation of matrix remodeling by SPARC in neoplastic progression

(2009) Alexandre Chlenski et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Systemic Endocrine Instigation of Indolent Tumor Growth Requires Osteopontin

(2008) Sandra S. McAllister et al.   CELL

A prototypic matricellular protein in the tumor microenvironment—Where there's SPARC, there's fire

(2008) Clancy J. Clark et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Endogenous human microRNAs that suppress breast cancer metastasis

(2008) Sohail F. Tavazoie et al.   NATURE

Identification of VEGF-regulated genes associated with increased lung metastatic potential: functional involvement of tenascin-C in tumor growth and lung metastasis

(2008) A Calvo et al.   ONCOGENE