Overcoming immunogenicity issues of HIV p24 antigen by the use of innovative nanostructured lipid carriers as delivery systems: evidences in mice and non-human primates

Rational design of nanoparticles towards targeting antigen-presenting cells and improved T cell priming

(2017) Eva Zupančič et al.   JOURNAL OF CONTROLLED RELEASE

Delivering adjuvants and antigens in separate nanoparticles eliminates the need of physical linkage for effective vaccination

(2017) Mona O. Mohsen et al.   JOURNAL OF CONTROLLED RELEASE

Tackling HIV and AIDS: contributions by non-human primate models

(2017) Koen K A Van Rompay   LAB ANIMAL

Rhesus macaque and mouse models for down-selecting circumsporozoite protein based malaria vaccines differ significantly in immunogenicity and functional outcomes

(2017) Timothy W. Phares et al.   MALARIA JOURNAL

Intradermal injection of an anti-Langerin-HIVGag fusion vaccine targets epidermal Langerhans cells in nonhuman primates and can be tracked in vivo

(2016) Nina Salabert et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Enhancing dendritic cell activation and HIV vaccine effectiveness through nanoparticle vaccination

(2016) Joshua J. Glass et al.   Expert Review of Vaccines

Adjuvant-dependent innate and adaptive immune signatures of risk of SIVmac251 acquisition

(2016) Monica Vaccari et al.   NATURE MEDICINE

COMPASS identifies T-cell subsets correlated with clinical outcomes

(2015) Lin Lin et al.   NATURE BIOTECHNOLOGY

Immunopotentiator-Loaded Polymeric Microparticles as Robust Adjuvant to Improve Vaccine Efficacy

(2015) Weifeng Zhang et al.   PHARMACEUTICAL RESEARCH

HIV specific responses induced in nonhuman primates with ANRS HIV-Lipo-5 vaccine combined with rMVA-HIV prime or boost immunizations

(2015) Nathalie Dereuddre-Bosquet et al.   VACCINE

Delivering HIV Gagp24 to DCIR Induces Strong Antibody Responses In Vivo

(2015) Anne-Laure Flamar et al.   PLoS One

Continued Follow-Up of Phambili Phase 2b Randomized HIV-1 Vaccine Trial Participants Supports Increased HIV-1 Acquisition among Vaccinated Men

(2015) Zoe Moodie et al.   PLoS One

Macrophage- and Neutrophil-Derived TNF-α Instructs Skin Langerhans Cells To Prime Antiviral Immune Responses

(2014) Olivier Epaulard et al.   JOURNAL OF IMMUNOLOGY

Vaccine-Induced IgG Antibodies to V1V2 Regions of Multiple HIV-1 Subtypes Correlate with Decreased Risk of HIV-1 Infection

(2014) Susan Zolla-Pazner et al.   PLoS One

HIV-1 Conserved Elements p24CE DNA Vaccine Induces Humoral Immune Responses with Broad Epitope Recognition in Macaques

(2014) Viraj Kulkarni et al.   PLoS One

Adjuvant-carrying synthetic vaccine particles augment the immune response to encapsulated antigen and exhibit strong local immune activation without inducing systemic cytokine release

(2014) Petr O. Ilyinskii et al.   VACCINE

Vaccine-induced plasma IgA specific for the C1 region of the HIV-1 envelope blocks binding and effector function of IgG

(2013) G. D. Tomaras et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Immunobiology of Toll-Like Receptor 4 Agonists

(2013) Julia K. Bohannon et al.   SHOCK

Nanoparticle vaccines

(2013) Liang Zhao et al.   VACCINE

Adjuvant Effect of Cationic Liposomes for Subunit Influenza Vaccine: Influence of Antigen Loading Method, Cholesterol and Immune Modulators

(2013) Christophe Barnier-Quer et al.   Pharmaceutics

Releasable Layer-by-Layer Assembly of Stabilized Lipid Nanocapsules on Microneedles for Enhanced Transcutaneous Vaccine Delivery

(2012) Peter C. DeMuth et al.   ACS Nano

Adjuvants for human vaccines

(2012) Carl R Alving et al.   CURRENT OPINION IN IMMUNOLOGY

CD34-derived dendritic cells transfected ex vivo with HIV-Gag mRNA induce polyfunctional T-cell responses in nonhuman primates

(2012) Gabrielle Romain et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Lipid Nanoparticle Vectorization of IndoCyanine Green Improves Fluorescence Imaging for Tumor Diagnosis and Lymph Node Resection

(2012) Fabrice P. Navarro et al.   Journal of Biomedical Nanotechnology

Lessons learned from HIV-1 vaccine trials: new priorities and directions

(2012) Andrew J McMichael et al.   NATURE IMMUNOLOGY

Immune-Correlates Analysis of an HIV-1 Vaccine Efficacy Trial

(2012) Barton F. Haynes et al.   NEW ENGLAND JOURNAL OF MEDICINE

CpG DNA as a vaccine adjuvant

(2011) Christian Bode et al.   Expert Review of Vaccines

How To Prepare and Stabilize Very Small Nanoemulsions

(2011) Thomas Delmas et al.   LANGMUIR

Immunization with HIV Gag targeted to dendritic cells followed by recombinant New York vaccinia virus induces robust T-cell immunity in nonhuman primates

(2011) B. J. Flynn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Comparison of Immunologic Assays for Detecting Immune Responses in HIV Immunotherapeutic Studies: AIDS Clinical Trials Group Trial A5181

(2010) B. J. C. Macatangay et al.   Clinical and Vaccine Immunology

Virus-like particles in vaccine development

(2010) António Roldão et al.   Expert Review of Vaccines

Administration routes affect the quality of immune responses: A cross-sectional evaluation of particulate antigen-delivery systems

(2010) Deepa Mohanan et al.   JOURNAL OF CONTROLLED RELEASE

TLR9-Targeted Biodegradable Nanoparticles as Immunization Vectors Protect against West Nile Encephalitis

(2010) S. L. Demento et al.   JOURNAL OF IMMUNOLOGY

3D visualization of HIV transfer at the virological synapse between dendritic cells and T cells

(2010) R. L. Felts et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Comparison of T cell immune responses induced by vectored HIV vaccines in non-human primates and humans

(2010) Andrew J. Bett et al.   VACCINE

Co-encapsulation of antigen and Toll-like receptor ligand in cationic liposomes affects the quality of the immune response in mice after intradermal vaccination

(2010) Suzanne M. Bal et al.   VACCINE

HIV vaccines: lessons learned and the way forward

(2010) Jerome H Kim et al.   Current Opinion in HIV and AIDS

Concomitant delivery of a CTL-restricted peptide antigen and CpG ODN by PLGA microparticles induces cellular immune response

(2009) Stefan Fischer et al.   JOURNAL OF DRUG TARGETING

The role of IFN-γ Elispot assay in HIV vaccine research

(2009) Hendrik Streeck et al.   Nature Protocols

Vaccination with ALVAC and AIDSVAX to Prevent HIV-1 Infection in Thailand

(2009) Supachai Rerks-Ngarm et al.   NEW ENGLAND JOURNAL OF MEDICINE

Immune response by nasal delivery of hepatitis B surface antigen and codelivery of a CpG ODN in alginate coated chitosan nanoparticles

(2008) Olga Borges et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

HIV-1 vaccine-induced immunity in the test-of-concept Step Study: a case–cohort analysis

(2008) M Juliana McElrath et al.   LANCET

Efficacy assessment of a cell-mediated immunity HIV-1 vaccine (the Step Study): a double-blind, randomised, placebo-controlled, test-of-concept trial

(2008) Susan P Buchbinder et al.   LANCET

Broad and Gag-Biased HIV-1 Epitope Repertoires Are Associated with Lower Viral Loads

(2008) Morgane Rolland et al.   PLoS One

Immunological decision-making: how does the immune system decide to mount a helper T-cell response?

(2007) Gerard E. Kaiko et al.   IMMUNOLOGY