HIV-1 Conserved Elements p24CE DNA Vaccine Induces Humoral Immune Responses with Broad Epitope Recognition in Macaques

Altered Response Hierarchy and Increased T-Cell Breadth upon HIV-1 Conserved Element DNA Vaccination in Macaques

(2014) Viraj Kulkarni et al.   PLoS One

Virological, Immune and Host genetics Markers in the Control of HIV Infection

(2013) Beatriz Mothe et al.   DISEASE MARKERS

Vaccine-Induced Gag-Specific T Cells Are Associated With Reduced Viremia After HIV-1 Infection

(2013) Holly Janes et al.   JOURNAL OF INFECTIOUS DISEASES

Association of HLA-DRB1–restricted CD4+ T cell responses with HIV immune control

(2013) Srinika Ranasinghe et al.   NATURE MEDICINE

HIV-1 p24gag Derived Conserved Element DNA Vaccine Increases the Breadth of Immune Response in Mice

(2013) Viraj Kulkarni et al.   PLoS One

Isotype-switched immunoglobulin G antibodies to HIV Gag proteins may provide alternative or additional immune responses to ‘protective’ human leukocyte antigen-B alleles in HIV controllers

(2012) Martyn A. French et al.   AIDS

Full-Length HIV-1 Immunogens Induce Greater Magnitude and Comparable Breadth of T Lymphocyte Responses to Conserved HIV-1 Regions Compared with Conserved-Region-Only HIV-1 Immunogens in Rhesus Monkeys

(2012) K. E. Stephenson et al.   JOURNAL OF VIROLOGY

CTL Responses of High Functional Avidity and Broad Variant Cross-Reactivity Are Associated with HIV Control

(2012) Beatriz Mothe et al.   PLoS One

Broad and Cross-Clade CD4+ T-Cell Responses Elicited by a DNA Vaccine Encoding Highly Conserved and Promiscuous HIV-1 M-Group Consensus Peptides

(2012) Rafael Ribeiro Almeida et al.   PLoS One

Prime-boost regimens with adjuvanted synthetic long peptides elicit T cells and antibodies to conserved regions of HIV-1 in macaques

(2011) Maximillian Rosario et al.   AIDS

HIV-Specific CD4 T Cell Responses to Different Viral Proteins Have Discordant Associations with Viral Load and Clinical Outcome

(2011) S. Ranasinghe et al.   JOURNAL OF VIROLOGY

A DNA Vaccine Encoding Multiple HIV CD4 Epitopes Elicits Vigorous Polyfunctional, Long-Lived CD4+ and CD8+ T Cell Responses

(2011) Daniela Santoro Rosa et al.   PLoS One

Coordinate linkage of HIV evolution reveals regions of immunological vulnerability

(2011) V. Dahirel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Preclinical evaluation of HIV-1 therapeutic ex vivo dendritic cell vaccines expressing consensus Gag antigens and conserved Gag epitopes

(2011) Liguo Niu et al.   VACCINE

Focus and breadth of cellular immune responses elicited by a heterologous insert prime-boost vaccine regimen in rhesus monkeys

(2011) David R. Kaufman et al.   VACCINE

Vaccine-induced IgG2 anti-HIV p24 is associated with control of HIV in patients with a ‘high-affinity’ FcγRIIa genotype

(2010) Martyn A French et al.   AIDS

IgG Subclass Profiles in Infected HIV Type 1 Controllers and Chronic Progressors and in Uninfected Recipients of Env Vaccines

(2010) Kaustuv Banerjee et al.   AIDS RESEARCH AND HUMAN RETROVIRUSES

Long peptides induce polyfunctional T cells against conserved regions of HIV-1 with superior breadth to single-gene vaccines in macaques

(2010) Maximillian Rosario et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Mosaic HIV-1 vaccines expand the breadth and depth of cellular immune responses in rhesus monkeys

(2010) Dan H Barouch et al.   NATURE MEDICINE

Mosaic vaccines elicit CD8+ T lymphocyte responses that confer enhanced immune coverage of diverse HIV strains in monkeys

(2010) Sampa Santra et al.   NATURE MEDICINE

A Vaccine Encoding Conserved Promiscuous HIV CD4 Epitopes Induces Broad T Cell Responses in Mice Transgenic to Multiple Common HLA Class II Molecules

(2010) Susan Pereira Ribeiro et al.   PLoS One

Comparison of Immunogen Designs That Optimize Peptide Coverage: Reply to Fischer et al.

(2008) David C. Nickle et al.   PLoS Computational Biology

Identification of immunogenic HLA-B7 “Achilles’ heel” epitopes within highly conserved regions of HIV

(2008) Anne S. De Groot et al.   VACCINE