Endoplasmic reticulum stress in hepatic steatosis and inflammatory bowel diseases
Published 2014 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Endoplasmic reticulum stress in hepatic steatosis and inflammatory bowel diseases
Authors
Keywords
-
Journal
Frontiers in Genetics
Volume 5, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2014-07-25
DOI
10.3389/fgene.2014.00242
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Modulation of endoplasmic reticulum (ER) stress-induced autophagy by C/EBP homologous protein (CHOP) and inositol-requiring enzyme 1α (IRE1α) in human colon cancer cells
- (2014) Yosuke Shimodaira et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- The endoplasmic reticulum stress markers GRP78 and CHOP predict disease-free survival and responsiveness to chemotherapy in breast cancer
- (2014) Yi-Zi Zheng et al. BREAST CANCER RESEARCH AND TREATMENT
- Activated ERBB2/HER2 Licenses Sensitivity to Apoptosis upon Endoplasmic Reticulum Stress through a PERK-Dependent Pathway
- (2014) Rosa Martín-Pérez et al. CANCER RESEARCH
- Targeting the unfolded protein response in heart diseases
- (2014) Man Liu et al. EXPERT OPINION ON THERAPEUTIC TARGETS
- TLR dependent XBP-1 activation induces an autocrine loop in rheumatoid arthritis synoviocytes
- (2014) Sinisa Savic et al. JOURNAL OF AUTOIMMUNITY
- Cutting Edge: Endoplasmic Reticulum Stress Licenses Macrophages To Produce Mature IL-1 in Response to TLR4 Stimulation through a Caspase-8- and TRIF-Dependent Pathway
- (2014) K. Shenderov et al. JOURNAL OF IMMUNOLOGY
- Inflammasome activation has an important role in the development of spontaneous colitis
- (2014) J Zhang et al. Mucosal Immunology
- The unfolded-protein-response sensor IRE-1α regulates the function of CD8α+ dendritic cells
- (2014) Fabiola Osorio et al. NATURE IMMUNOLOGY
- Mechanistic rationale for targeting the unfolded protein response in pre-B acute lymphoblastic leukemia
- (2014) B. Kharabi Masouleh et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- X Box-Binding Protein 1 Regulates Angiogenesis in Human Pancreatic Adenocarcinomas
- (2014) Lorenzo Romero-Ramirez et al. Translational Oncology
- Lipotoxic endoplasmic reticulum stress, β cell failure, and type 2 diabetes mellitus
- (2014) Trevor J. Biden et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- Unfolded protein response in hepatitis C virus infection
- (2014) Shiu-Wan Chan Frontiers in Microbiology
- A new paradigm: innate immune sensing of viruses via the unfolded protein response
- (2014) Judith A. Smith Frontiers in Microbiology
- Stress responses in flavivirus-infected cells: activation of unfolded protein response and autophagy
- (2014) Ana-Belén Blázquez et al. Frontiers in Microbiology
- ER stress and hepatic lipid metabolism
- (2014) Huiping Zhou et al. Frontiers in Genetics
- CD40 deficiency in mice exacerbates obesity-induced adipose tissue inflammation, hepatic steatosis, and insulin resistance
- (2013) Chang-An Guo et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Immune Chaperone gp96 Drives the Contributions of Macrophages to Inflammatory Colon Tumorigenesis
- (2013) Crystal Morales et al. CANCER RESEARCH
- Wnt signaling in adult intestinal stem cells and cancer
- (2013) Michaela Krausova et al. CELLULAR SIGNALLING
- Toll-like receptor-mediated IRE1α activation as a therapeutic target for inflammatory arthritis
- (2013) Quan Qiu et al. EMBO JOURNAL
- Cellular stress response and innate immune signaling: integrating pathways in host defense and inflammation
- (2013) Sujatha Muralidharan et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Identification of endoplasmic reticulum stress-inducing agents by antagonizing autophagy: a new potential strategy for identification of anti-cancer therapeutics in B-cell malignancies
- (2013) Emilia Mahoney et al. LEUKEMIA & LYMPHOMA
- Paneth cells as a site of origin for intestinal inflammation
- (2013) Timon E. Adolph et al. NATURE
- ER-stress-induced transcriptional regulation increases protein synthesis leading to cell death
- (2013) Jaeseok Han et al. NATURE CELL BIOLOGY
- GRP78 as a regulator of liver steatosis and cancer progression mediated by loss of the tumor suppressor PTEN
- (2013) W-T Chen et al. ONCOGENE
- Essential roles of grp94 in gut homeostasis via chaperoning canonical Wnt pathway
- (2013) B. Liu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The UPR in atherosclerosis
- (2013) Alex X. Zhou et al. Seminars in Immunopathology
- The Adaptive Endoplasmic Reticulum Stress Response to Lipotoxicity in Progressive Human Nonalcoholic Fatty Liver Disease
- (2013) April D. Lake et al. TOXICOLOGICAL SCIENCES
- An ERcentric view of Parkinson's disease
- (2013) Gabriela Mercado et al. TRENDS IN MOLECULAR MEDICINE
- Endoplasmic Reticulum Stress, Pancreatic -Cell Degeneration, and Diabetes
- (2013) F. R. Papa Cold Spring Harbor Perspectives in Medicine
- Endoplasmic Reticulum Stress in Nonalcoholic Fatty Liver Disease
- (2012) Michael J. Pagliassotti Annual Review of Nutrition
- CD147 induces UPR to inhibit apoptosis and chemosensitivity by increasing the transcription of Bip in hepatocellular carcinoma
- (2012) J Tang et al. CELL DEATH AND DIFFERENTIATION
- Thioredoxin-Interacting Protein Mediates ER Stress-Induced β Cell Death through Initiation of the Inflammasome
- (2012) Christine M. Oslowski et al. Cell Metabolism
- IRE1α Induces Thioredoxin-Interacting Protein to Activate the NLRP3 Inflammasome and Promote Programmed Cell Death under Irremediable ER Stress
- (2012) Alana G. Lerner et al. Cell Metabolism
- A Myriad of Pathways to NASH
- (2012) Soledad Larrain et al. Clinics in Liver Disease
- Unfolded Protein Response in Chronic Obstructive Pulmonary Disease: Smoking, Aging and Disease: A SAD Trifecta
- (2012) A. Blumental-Perry CURRENT MOLECULAR MEDICINE
- Nonalcoholic fatty liver disease and lipids
- (2012) Anthony S. Wierzbicki et al. CURRENT OPINION IN LIPIDOLOGY
- Nonalcoholic Fatty Liver Disease/Steatohepatitis: Epidemiology, Pathogenesis, Clinical Presentation and Treatment
- (2012) Sandra Milic et al. DIGESTIVE DISEASES
- Protective and Aggravating Effects of Nlrp3 Inflammasome Activation in IBD Models: Influence of Genetic and Environmental Factors
- (2012) Christian Bauer et al. DIGESTIVE DISEASES
- Endoplasmic Reticulum Stress and Inflammation
- (2012) Timon-Eric Adolph et al. DIGESTIVE DISEASES
- Targeting the UPR transcription factor XBP1 protects against Huntington's disease through the regulation of FoxO1 and autophagy
- (2012) Rene L. Vidal et al. HUMAN MOLECULAR GENETICS
- CHOP is a multifunctional transcription factor in the ER stress response
- (2012) H. Nishitoh JOURNAL OF BIOCHEMISTRY
- IL-1 receptor antagonist ameliorates inflammasome-dependent alcoholic steatohepatitis in mice
- (2012) Jan Petrasek et al. JOURNAL OF CLINICAL INVESTIGATION
- A novel pathogenic role of the ER chaperone GRP78/BiP in rheumatoid arthritis
- (2012) Seung-Ah Yoo et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Inflammasomes in liver diseases
- (2012) Gyongyi Szabo et al. JOURNAL OF HEPATOLOGY
- Atypical Activation of the Unfolded Protein Response in Cystic Fibrosis Airway Cells Contributes to p38 MAPK-Mediated Innate Immune Responses
- (2012) C. J. Blohmke et al. JOURNAL OF IMMUNOLOGY
- Nonalcoholic fatty liver disease: Current and potential therapies
- (2012) Mohamed Abdellah Ibrahim et al. LIFE SCIENCES
- Increased expression of ER stress- and hypoxia-associated molecules in grey matter lesions in multiple sclerosis
- (2012) JM McMahon et al. Multiple Sclerosis Journal
- Host–microbe interactions have shaped the genetic architecture of inflammatory bowel disease
- (2012) Luke Jostins et al. NATURE
- Inflammasome-mediated dysbiosis regulates progression of NAFLD and obesity
- (2012) Jorge Henao-Mejia et al. NATURE
- Toll-like receptor activation suppresses ER stress factor CHOP and translation inhibition through activation of eIF2B
- (2012) Connie W. Woo et al. NATURE CELL BIOLOGY
- A role for the NLRP3 inflammasome in metabolic diseases—did Warburg miss inflammation?
- (2012) Haitao Wen et al. NATURE IMMUNOLOGY
- Regulation of inflammasome signaling
- (2012) Vijay A K Rathinam et al. NATURE IMMUNOLOGY
- Inflammasomes: far beyond inflammation
- (2012) Jorge Henao-Mejia et al. NATURE IMMUNOLOGY
- Chemotherapy-triggered cathepsin B release in myeloid-derived suppressor cells activates the Nlrp3 inflammasome and promotes tumor growth
- (2012) Mélanie Bruchard et al. NATURE MEDICINE
- Dysbiosis driven by inflammasome deficiency exacerbates hepatic steatosis and governs rate of NAFLD progression
- (2012) Natalie J. Wood Nature Reviews Gastroenterology & Hepatology
- The unfolded protein response: controlling cell fate decisions under ER stress and beyond
- (2012) Claudio Hetz NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Direct Association of Unfolded Proteins with Mammalian ER Stress Sensor, IRE1β
- (2012) Daisuke Oikawa et al. PLoS One
- ER Stress Activates NF-κB by Integrating Functions of Basal IKK Activity, IRE1 and PERK
- (2012) Arvin B. Tam et al. PLoS One
- IRE1 Cleaves Select microRNAs During ER Stress to Derepress Translation of Proapoptotic Caspase-2
- (2012) J.-P. Upton et al. SCIENCE
- Nonalcoholic Fatty Liver Disease: Pathologic Patterns and Biopsy Evaluation in Clinical Research
- (2012) David Kleiner et al. SEMINARS IN LIVER DISEASE
- Pharmacologic ER stress induces non-alcoholic steatohepatitis in an animal model
- (2012) Jin-Sook Lee et al. TOXICOLOGY LETTERS
- ER stress-induced inflammation: does it aid or impede disease progression?
- (2012) Abhishek D. Garg et al. TRENDS IN MOLECULAR MEDICINE
- Genetically modified mouse models for the study of nonalcoholic fatty liver disease
- (2012) Perumal Nagarajan WORLD JOURNAL OF GASTROENTEROLOGY
- ER stress activates the NLRP3 inflammasome via an UPR-independent pathway
- (2012) P Menu et al. Cell Death & Disease
- Obesity-induced endoplasmic reticulum stress causes chronic inflammation in adipose tissue
- (2012) Noritaka Kawasaki et al. Scientific Reports
- Non-alcoholic fatty liver disease
- (2012) Ana C. TUYAMA et al. Journal of Diabetes
- Obesity and endoplasmic reticulum (ER) stresses
- (2012) Yamini B. Tripathi et al. Frontiers in Immunology
- Defective IL10 Signaling Defining a Subgroup of Patients With Inflammatory Bowel Disease
- (2011) Bernadette Begue et al. AMERICAN JOURNAL OF GASTROENTEROLOGY
- The Inflammasome NLRs in Immunity, Inflammation, and Associated Diseases
- (2011) Beckley K. Davis et al. Annual Review of Immunology
- Inflammasome-mediated suppression of inflammation-induced colorectal cancer progression is mediated by direct regulation of epithelial cell proliferation
- (2011) Bo Hu et al. CELL CYCLE
- mTORC1 serves ER stress-triggered apoptosis via selective activation of the IRE1–JNK pathway
- (2011) H Kato et al. CELL DEATH AND DIFFERENTIATION
- Activation of cell stress response pathways by Shiga toxins
- (2011) Vernon L. Tesh CELLULAR MICROBIOLOGY
- The NLRP3 inflammasome in health and disease: the good, the bad and the ugly
- (2011) P. Menu et al. CLINICAL AND EXPERIMENTAL IMMUNOLOGY
- The unfolded protein response transducer IRE1α prevents ER stress-induced hepatic steatosis
- (2011) Kezhong Zhang et al. EMBO JOURNAL
- Inflammasomes in Intestinal Inflammation and Cancer
- (2011) Grace Y. Chen et al. GASTROENTEROLOGY
- Crohn's disease: NOD2, autophagy and ER stress converge
- (2011) T. Fritz et al. GUT
- Liver-specific loss of glucose-regulated protein 78 perturbs the unfolded protein response and exacerbates a spectrum of liver diseases in mice
- (2011) Cheng Ji et al. HEPATOLOGY
- Toll-like Receptors and Their Crosstalk with Other Innate Receptors in Infection and Immunity
- (2011) Taro Kawai et al. IMMUNITY
- Sensing damage by the NLRP3 inflammasome
- (2011) Jaklien C. Leemans et al. IMMUNOLOGICAL REVIEWS
- Influence of the Hepatic Eukaryotic Initiation Factor 2α (eIF2α) Endoplasmic Reticulum (ER) Stress Response Pathway on Insulin-mediated ER Stress and Hepatic and Peripheral Glucose Metabolism
- (2011) Andreas L. Birkenfeld et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Accumulation of endoplasmic reticulum stress and lipogenesis in the liver through generational effects of high fat diets
- (2011) Jiong Li et al. JOURNAL OF HEPATOLOGY
- A Functional Role for Nlrp6 in Intestinal Inflammation and Tumorigenesis
- (2011) G. Y. Chen et al. JOURNAL OF IMMUNOLOGY
- Expression profiles of endoplasmic reticulum stress-related molecules in demyelinating lesions and multiple sclerosis
- (2011) Paula Cunnea et al. Multiple Sclerosis Journal
- Linking the inflammasome to obesity-related disease
- (2011) Tiffany Horng et al. NATURE MEDICINE
- The NLRP3 inflammasome instigates obesity-induced inflammation and insulin resistance
- (2011) Bolormaa Vandanmagsar et al. NATURE MEDICINE
- HCV Causes Chronic Endoplasmic Reticulum Stress Leading to Adaptation and Interference with the Unfolded Protein Response
- (2011) Emmanuelle Merquiol et al. PLoS One
- Inflammasome is a central player in the induction of obesity and insulin resistance
- (2011) R. Stienstra et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Transmission of endoplasmic reticulum stress and pro-inflammation from tumor cells to myeloid cells
- (2011) N. R. Mahadevan et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Stressed out about obesity: IRE1α–XBP1 in metabolic disorders
- (2011) Haibo Sha et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- Endoplasmic reticulum stress, obesity and diabetes
- (2011) Miriam Cnop et al. TRENDS IN MOLECULAR MEDICINE
- ER stress and the unfolded protein response in intestinal inflammation
- (2010) Michael A. McGuckin et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- Autophagy
- (2010) Lijun Zhou et al. Autophagy
- Pattern Recognition Receptors and Inflammation
- (2010) Osamu Takeuchi et al. CELL
- Defective Hepatic Autophagy in Obesity Promotes ER Stress and Causes Insulin Resistance
- (2010) Ling Yang et al. Cell Metabolism
- The critical role of GRP78 in physiologic and pathologic stress
- (2010) Kyle T Pfaffenbach et al. CURRENT OPINION IN CELL BIOLOGY
- Colitis induced in mice with dextran sulfate sodium (DSS) is mediated by the NLRP3 inflammasome
- (2010) C. Bauer et al. GUT
- The NLRP3 Inflammasome Protects against Loss of Epithelial Integrity and Mortality during Experimental Colitis
- (2010) Md. Hasan Zaki et al. IMMUNITY
- Control of Intestinal Homeostasis, Colitis, and Colitis-Associated Colorectal Cancer by the Inflammatory Caspases
- (2010) Jeremy Dupaul-Chicoine et al. IMMUNITY
- IL-23/IL-17 axis in IBD
- (2010) Massimiliano Sarra et al. INFLAMMATORY BOWEL DISEASES
- NLRP3 inflammasome plays a key role in the regulation of intestinal homeostasis
- (2010) Simon A. Hirota et al. INFLAMMATORY BOWEL DISEASES
- The NLRP3 inflammasome functions as a negative regulator of tumorigenesis during colitis-associated cancer
- (2010) Irving C. Allen et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Endoplasmic reticulum stress in liver disease
- (2010) Harmeet Malhi et al. JOURNAL OF HEPATOLOGY
- Induction of the unfolded protein response by α-synuclein in experimental models of Parkinson’s disease
- (2010) Arianna Bellucci et al. JOURNAL OF NEUROCHEMISTRY
- An intestinal epithelial defect conferring ER stress results in inflammation involving both innate and adaptive immunity
- (2010) R D Eri et al. Mucosal Immunology
- Innate lymphoid cells drive interleukin-23-dependent innate intestinal pathology
- (2010) Sofia Buonocore et al. NATURE
- TLR activation of the transcription factor XBP1 regulates innate immune responses in macrophages
- (2010) Fabio Martinon et al. NATURE IMMUNOLOGY
- How the Noninflammasome NLRs Function in the Innate Immune System
- (2010) J. P. Y. Ting et al. SCIENCE
- NF- B: Much Learned, Much to Learn
- (2010) B. Razani et al. Science Signaling
- ER Stress in Pancreatic Cells: The Thin Red Line Between Adaptation and Failure
- (2010) D. L. Eizirik et al. Science Signaling
- BiP Binding to the ER-Stress Sensor Ire1 Tunes the Homeostatic Behavior of the Unfolded Protein Response
- (2010) David Pincus et al. PLOS BIOLOGY
- XBP1: the last two decades
- (2009) L H Glimcher ANNALS OF THE RHEUMATIC DISEASES
- gp96, an endoplasmic reticulum master chaperone for integrins and Toll-like receptors, selectively regulates early T and B lymphopoiesis
- (2009) M. Staron et al. BLOOD
- Grp78 Heterozygosity Promotes Adaptive Unfolded Protein Response and Attenuates Diet-Induced Obesity and Insulin Resistance
- (2009) R. Ye et al. DIABETES
- GRP78 expression inhibits insulin and ER stress–induced SREBP-1c activation and reduces hepatic steatosis in mice
- (2009) Hélène L. Kammoun et al. JOURNAL OF CLINICAL INVESTIGATION
- Acetaminophen-induced hepatotoxicity in mice is dependent on Tlr9 and the Nalp3 inflammasome
- (2009) Avlin B. Imaeda et al. JOURNAL OF CLINICAL INVESTIGATION
- Activation of the Akt-NF- B Pathway by Subtilase Cytotoxin through the ATF6 Branch of the Unfolded Protein Response
- (2009) H. Yamazaki et al. JOURNAL OF IMMUNOLOGY
- Adaptive suppression of the ATF4–CHOP branch of the unfolded protein response by toll-like receptor signalling
- (2009) Connie W. Woo et al. NATURE CELL BIOLOGY
- Activation of the NLRP3 inflammasome in dendritic cells induces IL-1β–dependent adaptive immunity against tumors
- (2009) François Ghiringhelli et al. NATURE MEDICINE
- The NLRP3 inflammasome: A sensor of immune danger signals
- (2009) Suzanne L. Cassel et al. SEMINARS IN IMMUNOLOGY
- HCV Induces Oxidative and ER Stress, and Sensitizes Infected Cells to Apoptosis in SCID/Alb-uPA Mice
- (2009) Michael A. Joyce et al. PLoS Pathogens
- IL-23 and Autoimmunity: New Insights into the Pathogenesis of Inflammatory Bowel Disease
- (2008) Clara Abraham et al. Annual Review of Medicine
- Endoplasmic reticulum HSP90b1 (gp96, grp94) optimizes B-cell function via chaperoning integrin and TLR but not immunoglobulin
- (2008) B. Liu et al. BLOOD
- XBP1 Links ER Stress to Intestinal Inflammation and Confers Genetic Risk for Human Inflammatory Bowel Disease
- (2008) Arthur Kaser et al. CELL
- Contributions of IBD5, IL23R, ATG16L1, and NOD2 to Crohnʼs disease risk in a population-based case-control study: Evidence of gene–gene interactions
- (2008) Toshihiko Okazaki et al. INFLAMMATORY BOWEL DISEASES
- Endoplasmic reticulum stress and the pancreatic acinar cell
- (2008) Constanze H Kubisch et al. Expert Review of Gastroenterology & Hepatology
Create your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create NowAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started