GRP78 as a regulator of liver steatosis and cancer progression mediated by loss of the tumor suppressor PTEN

Molecular Pathways: The Complex Roles of Inflammation Pathways in the Development and Treatment of Liver Cancer

(2013) K. Nikolaou et al.   CLINICAL CANCER RESEARCH

Clusterin Protects Hepatocellular Carcinoma Cells from Endoplasmic Reticulum Stress Induced Apoptosis through GRP78

(2013) Cun Wang et al.   PLoS One

ER Stress Causes Rapid Loss of Intestinal Epithelial Stemness through Activation of the Unfolded Protein Response

(2013) Jarom Heijmans et al.   Cell Reports

GRP78 plays an essential role in adipogenesis and postnatal growth in mice

(2012) Genyuan Zhu et al.   FASEB JOURNAL

The critical roles of endoplasmic reticulum chaperones and unfolded protein response in tumorigenesis and anticancer therapies

(2012) B Luo et al.   ONCOGENE

Acute Inducible Ablation of GRP78 Reveals Its Role in Hematopoietic Stem Cell Survival, Lymphogenesis and Regulation of Stress Signaling

(2012) Shiuan Wey et al.   PLoS One

Beyond the endoplasmic reticulum: atypical GRP78 in cell viability, signalling and therapeutic targeting

(2011) Min Ni et al.   BIOCHEMICAL JOURNAL

Inducible knockout of GRP78/BiP in the hematopoietic system suppresses Pten-null leukemogenesis and AKT oncogenic signaling

(2011) S. Wey et al.   BLOOD

Spontaneous repopulation of β-catenin null livers with β-catenin-positive hepatocytes after chronic murine liver injury

(2011) Michael D. Thompson et al.   HEPATOLOGY

Liver-specific loss of glucose-regulated protein 78 perturbs the unfolded protein response and exacerbates a spectrum of liver diseases in mice

(2011) Cheng Ji et al.   HEPATOLOGY

Liver stem/progenitor cells: their characteristics and regulatory mechanisms

(2011) M. Tanaka et al.   JOURNAL OF BIOCHEMISTRY

Adaptive Basal Phosphorylation of eIF2  Is Responsible for Resistance to Cellular Stress-Induced Cell Death in Pten-Null Hepatocytes

(2011) N. Zeng et al.   MOLECULAR CANCER RESEARCH

The Endoplasmic Reticulum Chaperone Protein GRP94 Is Required for Maintaining Hematopoietic Stem Cell Interactions with the Adult Bone Marrow Niche

(2011) Biquan Luo et al.   PLoS One

Grp78 Heterozygosity Regulates Chaperone Balance in Exocrine Pancreas with Differential Response to Cerulein-Induced Acute Pancreatitis

(2010) Risheng Ye et al.   AMERICAN JOURNAL OF PATHOLOGY

Grp78 promotes the invasion of hepatocellular carcinoma

(2010) Rongjian Su et al.   BMC CANCER

ATF4 regulates lipid metabolism and thermogenesis

(2010) Chunxia Wang et al.   CELL RESEARCH

The critical role of GRP78 in physiologic and pathologic stress

(2010) Kyle T Pfaffenbach et al.   CURRENT OPINION IN CELL BIOLOGY

Expansion of Hepatic Tumor Progenitor Cells in Pten-Null Mice Requires Liver Injury and Is Reversed by Loss of AKT2

(2010) Vivian A. Galicia et al.   GASTROENTEROLOGY

Conditional β-catenin loss in mice promotes chemical hepatocarcinogenesis: Role of oxidative stress and platelet-derived growth factor receptor α/phosphoinositide 3-kinase signaling

(2010) Xu-Feng Zhang et al.   HEPATOLOGY

The role of signaling pathways in the development and treatment of hepatocellular carcinoma

(2010) S Whittaker et al.   ONCOGENE

Beta-catenin signaling, liver regeneration and hepatocellular cancer: Sorting the good from the bad

(2010) Kari Nichole Nejak-Bowen et al.   SEMINARS IN CANCER BIOLOGY

Liver-Specific β-Catenin Knockout Mice Exhibit Defective Bile Acid and Cholesterol Homeostasis and Increased Susceptibility to Diet-Induced Steatohepatitis

(2009) Jaideep Behari et al.   AMERICAN JOURNAL OF PATHOLOGY

GRP78: A Multifunctional Receptor on the Cell Surface

(2009) Mario Gonzalez–Gronow et al.   ANTIOXIDANTS & REDOX SIGNALING

Essential role of the unfolded protein response regulator GRP78/BiP in protection from neuronal apoptosis

(2009) M Wang et al.   CELL DEATH AND DIFFERENTIATION

Grp78 Heterozygosity Promotes Adaptive Unfolded Protein Response and Attenuates Diet-Induced Obesity and Insulin Resistance

(2009) R. Ye et al.   DIABETES

Regulation of PERK Signaling and Leukemic Cell Survival by a Novel Cytosolic Isoform of the UPR Regulator GRP78/BiP

(2009) Min Ni et al.   PLoS One

Pten null prostate tumorigenesis and AKT activation are blocked by targeted knockout of ER chaperone GRP78/BiP in prostate epithelium

(2008) Y. Fu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulation of Hepatic Lipogenesis by the Transcription Factor XBP1

(2008) A.-H. Lee et al.   SCIENCE