Inhibition of Chloride Intracellular Channel 1 (CLIC1) as Biguanide Class-Effect to Impair Human Glioblastoma Stem Cell Viability
Published 2018 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Inhibition of Chloride Intracellular Channel 1 (CLIC1) as Biguanide Class-Effect to Impair Human Glioblastoma Stem Cell Viability
Authors
Keywords
-
Journal
Frontiers in Pharmacology
Volume 9, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2018-08-21
DOI
10.3389/fphar.2018.00899
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- In vitro and in vivo characterization of stem-like cells from canine osteosarcoma and assessment of drug sensitivity
- (2018) Monica Gatti et al. EXPERIMENTAL CELL RESEARCH
- AMP kinase promotes glioblastoma bioenergetics and tumour growth
- (2018) Rishi Raj Chhipa et al. NATURE CELL BIOLOGY
- Pro-tumorigenic AMPK in glioblastoma
- (2018) Nektaria Maria Leli et al. NATURE CELL BIOLOGY
- Sprouty2 enhances the tumorigenic potential of glioblastoma cells
- (2018) Jong-Whi Park et al. NEURO-ONCOLOGY
- Development of an Injectable Slow-Release Metformin Formulation and Evaluation of Its Potential Antitumor Effects
- (2018) Sara Baldassari et al. Scientific Reports
- Metformin to Treat Cancer
- (2017) Samy Suissa EPIDEMIOLOGY
- Bioactivity and prostate tissue distribution of metformin in a preprostatectomy prostate cancer cohort
- (2017) Mike M. Nguyen et al. EUROPEAN JOURNAL OF CANCER PREVENTION
- Molecular markers in glioma
- (2017) Kirsten Ludwig et al. JOURNAL OF NEURO-ONCOLOGY
- Drug repurposing in cancer
- (2017) Linda Sleire et al. PHARMACOLOGICAL RESEARCH
- Different Effects of Human Umbilical Cord Mesenchymal Stem Cells on Glioblastoma Stem Cells by Direct Cell Interaction or Via Released Soluble Factors
- (2017) Adriana Bajetto et al. Frontiers in Cellular Neuroscience
- Metformin and temozolomide, a synergic option to overcome resistance in glioblastoma multiforme models
- (2017) Silvia Valtorta et al. Oncotarget
- The inhibition of FGF receptor 1 activity mediates sorafenib antiproliferative effects in human malignant pleural mesothelioma tumor-initiating cells
- (2017) Alessandra Pattarozzi et al. Stem Cell Research & Therapy
- Metformin Use Is Associated with Reduced Incidence and Improved Survival of Endometrial Cancer: A Meta-Analysis
- (2017) Yun-Liang Tang et al. Biomed Research International
- Metformin as an adjuvant treatment for cancer: a systematic review and meta-analysis
- (2016) C. Coyle et al. ANNALS OF ONCOLOGY
- Some leopards can change their spots: potential repositioning of stem cell reprogramming compounds as anti-cancer agents
- (2016) Woong-Hee Kim et al. CELL BIOLOGY AND TOXICOLOGY
- Drug-repositioning opportunities for cancer therapy: novel molecular targets for known compounds
- (2016) Roberto Würth et al. DRUG DISCOVERY TODAY
- NT1014, a novel biguanide, inhibits ovarian cancer growth in vitro and in vivo
- (2016) Lu Zhang et al. Journal of Hematology & Oncology
- Phenotypical and Pharmacological Characterization of Stem-Like Cells in Human Pituitary Adenomas
- (2016) Roberto Würth et al. MOLECULAR NEUROBIOLOGY
- Can you teach old drugs new tricks?
- (2016) Nicola Nosengo NATURE
- Novel celecoxib analogues inhibit glial production of prostaglandin E2, nitric oxide, and oxygen radicals reverting the neuroinflammatory responses induced by misfolded prion protein fragment 90-231 or lipopolysaccharide
- (2016) Valentina Villa et al. PHARMACOLOGICAL RESEARCH
- PPAR Gamma in Neuroblastoma: The Translational Perspectives of Hypoglycemic Drugs
- (2016) Serena Vella et al. PPAR Research
- Metformin potentiates anti-tumor effect of resveratrol on pancreatic cancer by down-regulation of VEGF-B signaling pathway
- (2016) Mengmeng Zhu et al. Oncotarget
- Inhibiting stemness and invasive properties of glioblastoma tumorsphere by combined treatment with temozolomide and a newly designed biguanide (HL156A)
- (2016) Junjeong Choi et al. Oncotarget
- Repurposing phenformin for the targeting of glioma stem cells and the treatment of glioblastoma
- (2016) Wei Jiang et al. Oncotarget
- Metformin treatment reduces temozolomide resistance of glioblastoma cells
- (2016) Seung Ho Yang et al. Oncotarget
- Therapeutic potential of the metabolic modulator phenformin in targeting the stem cell compartment in melanoma
- (2016) Tiziana Petrachi et al. Oncotarget
- Cellular prion protein controls stem cell-like properties of human glioblastoma tumor-initiating cells
- (2016) Alessandro Corsaro et al. Oncotarget
- Repurposing metformin for cancer treatment: current clinical studies
- (2016) Young Kwang Chae et al. Oncotarget
- Inhibition of the Autophagy Pathway Synergistically Potentiates the Cytotoxic Activity of Givinostat (ITF2357) on Human Glioblastoma Cancer Stem Cells
- (2016) Francesca Angeletti et al. Frontiers in Molecular Neuroscience
- Metformin inhibits the proliferation of human prostate cancer PC-3 cells via the downregulation of insulin-like growth factor 1 receptor
- (2015) Haruo Kato et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Chloride channels in cancer: Focus on chloride intracellular channel 1 and 4 (CLIC1 AND CLIC4) proteins in tumor development and as novel therapeutic targets
- (2015) Marta Peretti et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
- In vitro and in vivo antiproliferative activity of metformin on stem-like cells isolated from spontaneous canine mammary carcinomas: translational implications for human tumors
- (2015) Federica Barbieri et al. BMC CANCER
- Effects of Metformin, Buformin, and Phenformin on the Post-Initiation Stage of Chemically Induced Mammary Carcinogenesis in the Rat
- (2015) Z. Zhu et al. Cancer Prevention Research
- The histone demethylase KDM5A is a key factor for the resistance to temozolomide in glioblastoma
- (2015) Barbara Banelli et al. CELL CYCLE
- Drug repositioning and repurposing: terminology and definitions in literature
- (2015) Joris Langedijk et al. DRUG DISCOVERY TODAY
- The $2.6 Billion Pill — Methodologic and Policy Considerations
- (2015) Jerry Avorn NEW ENGLAND JOURNAL OF MEDICINE
- Single cell-derived clonal analysis of human glioblastoma links functional and genomic heterogeneity
- (2015) Mona Meyer et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Concise Review: Bullseye: Targeting Cancer Stem Cells to Improve the Treatment of Gliomas by Repurposing Disulfiram
- (2015) Joanna Triscott et al. STEM CELLS
- Metformin repositioning as antitumoral agent: selective antiproliferative effects in human glioblastoma stem cells, via inhibition of CLIC1-mediated ion current
- (2015) Marta Gritti et al. Oncotarget
- Metformin inhibition of neuroblastoma cell proliferation is differently modulated by cell differentiation induced by retinoic acid or overexpression of NDM29 non-coding RNA
- (2014) Delfina Costa et al. Cancer Cell International
- Metformin and Cancer Risk and Mortality: A Systematic Review and Meta-analysis Taking into Account Biases and Confounders
- (2014) S. Gandini et al. Cancer Prevention Research
- Reconstructing and Reprogramming the Tumor-Propagating Potential of Glioblastoma Stem-like Cells
- (2014) Mario L. Suvà et al. CELL
- Metformin: From Mechanisms of Action to Therapies
- (2014) Marc Foretz et al. Cell Metabolism
- Adiponectin as Novel Regulator of Cell Proliferation in Human Glioblastoma
- (2014) Carola Porcile et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Celecoxib Inhibits Prion Protein 90-231-Mediated Pro-inflammatory Responses in Microglial Cells
- (2014) Valentina Villa et al. MOLECULAR NEUROBIOLOGY
- NAC, Tiron and Trolox Impair Survival of Cell Cultures Containing Glioblastoma Tumorigenic Initiating Cells by Inhibition of Cell Cycle Progression
- (2014) Massimiliano Monticone et al. PLoS One
- Role of Metformin in Suppressing 1,2-Dimethylhydrazine-Induced Colon Cancer in Diabetic and Non-Diabetic Mice: Effect on Tumor Angiogenesis and Cell Proliferation
- (2014) Dalia K. Zaafar et al. PLoS One
- Metformin promotes autophagy and apoptosis in esophageal squamous cell carcinoma by downregulating Stat3 signaling
- (2014) Y Feng et al. Cell Death & Disease
- New Molecules and Old Drugs as Emerging Approaches to Selectively Target Human Glioblastoma Cancer Stem Cells
- (2014) Roberto Würth et al. Biomed Research International
- Sorafenib selectively depletes human glioblastoma tumor-initiating cells from primary cultures
- (2013) Elisa Carra et al. CELL CYCLE
- Functional Role of CLIC1 Ion Channel in Glioblastoma-Derived Stem/Progenitor Cells
- (2013) Matteo Setti et al. JNCI-Journal of the National Cancer Institute
- Inhibition of CXCL12/CXCR4 autocrine/paracrine loop reduces viability of human glioblastoma stem-like cells affecting self-renewal activity
- (2013) Monica Gatti et al. TOXICOLOGY
- Identification of a novel set of genes reflecting different in vivo invasive patterns of human GBM cells
- (2012) Massimiliano Monticone et al. BMC CANCER
- Identification of Drugs Including a Dopamine Receptor Antagonist that Selectively Target Cancer Stem Cells
- (2012) Eleftherios Sachlos et al. CELL
- Metformin selectively affects human glioblastoma tumor-initiating cell viability
- (2012) Roberto Würth et al. CELL CYCLE
- The status of the art of human malignant glioma management: the promising role of targeting tumor-initiating cells
- (2012) Tullio Florio et al. DRUG DISCOVERY TODAY
- Silencing of Eps8 blocks migration and invasion in human glioblastoma cell lines
- (2012) Maria Grazia Cattaneo et al. EXPERIMENTAL CELL RESEARCH
- Elevated expression of chloride intracellular channel 1 is correlated with poor prognosis in human gliomas
- (2012) Liang Wang et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- Glioma-Initiating Cell Elimination by Metformin Activation of FOXO3 via AMPK
- (2012) Atsushi Sato et al. Stem Cells Translational Medicine
- Metformin Inhibits Cell Proliferation, Migration and Invasion by Attenuating CSC Function Mediated by Deregulating miRNAs in Pancreatic Cancer Cells
- (2011) B. Bao et al. Cancer Prevention Research
- Metformin, Independent of AMPK, Induces mTOR Inhibition and Cell-Cycle Arrest through REDD1
- (2011) I. Ben Sahra et al. CANCER RESEARCH
- Deadly Teamwork: Neural Cancer Stem Cells and the Tumor Microenvironment
- (2011) Justin D. Lathia et al. Cell Stem Cell
- How to improve R&D productivity: the pharmaceutical industry's grand challenge
- (2010) Steven M. Paul et al. NATURE REVIEWS DRUG DISCOVERY
- Metformin Selectively Targets Cancer Stem Cells, and Acts Together with Chemotherapy to Block Tumor Growth and Prolong Remission
- (2009) H. A. Hirsch et al. CANCER RESEARCH
- Identification of Selective Inhibitors of Cancer Stem Cells by High-Throughput Screening
- (2009) Piyush B. Gupta et al. CELL
- Different Response of Human Glioma Tumor-initiating Cells to Epidermal Growth Factor Receptor Kinase Inhibitors
- (2009) Fabrizio Griffero et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial
- (2009) Roger Stupp et al. LANCET ONCOLOGY
- Epidermal Growth Factor Plays a Crucial Role in Mitogenic Regulation of Human Brain Tumor Stem Cells
- (2008) Akio Soeda et al. JOURNAL OF BIOLOGICAL CHEMISTRY
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started