Celecoxib Inhibits Prion Protein 90-231-Mediated Pro-inflammatory Responses in Microglial Cells

The deadly connection between endoplasmic reticulum, Ca2+, protein synthesis, and the endoplasmic reticulum stress response in malignant glioma cells

(2014) Guyla G. Johnson et al.   NEURO-ONCOLOGY

Therapy in Prion Diseases

(2013) Gianluigi Forloni et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Sulindac sulfide inhibits sarcoendoplasmic reticulum Ca2+ATPase, induces endoplasmic reticulum stress response, and exerts toxicity in glioma cells: Relevant similarities to and important differences from celecoxib

(2013) M.C. White et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Intracellular Ion Channel CLIC1: Involvement in Microglia-Mediated β-Amyloid Peptide(1-42) Neurotoxicity

(2013) Stephen D. Skaper et al.   NEUROCHEMICAL RESEARCH

Role of Prion Protein Aggregation in Neurotoxicity

(2012) Alessandro Corsaro et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Tryptophan hydroxylase 2 (TPH2) in a neuronal cell line: modulation by cell differentiation and NRSF/rest activity

(2012) Maria Teresa Gentile et al.   JOURNAL OF NEUROCHEMISTRY

Early Cytokine Elevation, PrPres Deposition, and Gliosis in Mouse Scrapie: No Effect on Disease by Deletion of Cytokine Genes IL-12p40 and IL-12p35

(2012) D. Tribouillard-Tanvier et al.   JOURNAL OF VIROLOGY

Neuroinflammation and Common Mechanism in Alzheimer’s Disease and Prion Amyloidosis: Amyloid-Associated Proteins, Neuroinflammation and Neurofibrillary Degeneration

(2012) Annemieke J.M. Rozemuller et al.   Neurodegenerative Diseases

Excitotoxicity Through NMDA Receptors Mediates Cerebellar Granule Neuron Apoptosis Induced by Prion Protein 90-231 Fragment

(2012) Stefano Thellung et al.   NEUROTOXICITY RESEARCH

Recombinant Human Prion Protein Fragment 90–231, a Useful Model to Study Prion Neurotoxicity

(2012) Alessandro Corsaro et al.   OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY

Calcium Binding Promotes Prion Protein Fragment 90–231 Conformational Change toward a Membrane Destabilizing and Cytotoxic Structure

(2012) Sacha Sorrentino et al.   PLoS One

The pathological prion protein forms ionic conductance in lipid bilayer

(2011) Daniele Paulis et al.   NEUROCHEMISTRY INTERNATIONAL

Purified high molecular weight synthetic Aβ(1–42) and biological Aβ oligomers are equipotent in rapidly inducing MTT formazan exocytosis

(2011) Adam M. Weidner et al.   NEUROSCIENCE LETTERS

Human PrP90-231-induced cell death is associated with intracellular accumulation of insoluble and protease-resistant macroaggregates and lysosomal dysfunction

(2011) S Thellung et al.   Cell Death & Disease

IL-27 inhibits OSM-mediated TNF-α and iNOS gene expression in microglia

(2010) Brandi J. Baker et al.   GLIA

High hydrophobic amino acid exposure is responsible of the neurotoxic effects induced by E200K or D202N disease-related mutations of the human prion protein

(2010) Alessandro Corsaro et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Engulfment of cerebral apoptotic bodies controls the course of prion disease in a mouse strain–dependent manner

(2010) Jan Kranich et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Efficacy of Novel Acridine Derivatives in the Inhibition of hPrP90-231 Prion Protein Fragment Toxicity

(2010) Valentina Villa et al.   NEUROTOXICITY RESEARCH

Inhibition of inducible NO synthase, cyclooxygenase-2 and interleukin-1β by torilin is mediated by mitogen-activated protein kinases in microglial BV2 cells

(2009) Y Choi et al.   BRITISH JOURNAL OF PHARMACOLOGY

Neuroinflammation in Prion Diseases: Concepts and Targets for Therapeutic Intervention

(2009) Constanze Riemer et al.   CNS & Neurological Disorders-Drug Targets

Safety and efficacy of quinacrine in human prion disease (PRION-1 study): a patient-preference trial

(2009) John Collinge et al.   LANCET NEUROLOGY

Dual Modulation of ERK1/2 and p38 MAP Kinase Activities Induced by Minocycline Reverses the Neurotoxic Effects of the Prion Protein Fragment 90–231

(2009) Alessandro Corsaro et al.   NEUROTOXICITY RESEARCH

Proteomic Profiling of Proliferating and Differentiated Neural mes-c-myc A1 Cell Line from Mouse Embryonic Mesencephalon by LC−MS

(2008) Angela Chambery et al.   JOURNAL OF PROTEOME RESEARCH

Why neurodegenerative diseases are progressive: uncontrolled inflammation drives disease progression

(2008) Hui-Ming Gao et al.   TRENDS IN IMMUNOLOGY