4.8 Editorial Material

Pro-tumorigenic AMPK in glioblastoma

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NATURE CELL BIOLOGY
Volume 20, Issue 7, Pages 736-737

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NATURE PUBLISHING GROUP
DOI: 10.1038/s41556-018-0129-9

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AMPK is a key metabolic sensor promoting cellular energy homeostasis under low-nutrient conditions and other stresses. However, its role in cancer is context-dependent and not fully understood. A study now shows that glioma stem cells co-opt an AMPK-dependent pathway to rewire metabolism, promoting tumour growth.

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