Evidence of Inflammatory System Involvement in Parkinson’s Disease

A Complex Proinflammatory Role for Peripheral Monocytes in Alzheimer's Disease

(2018) Marina Saresella et al.   JOURNAL OF ALZHEIMERS DISEASE

Matrix metalloproteinase-3 is a possible mediator of neurodevelopmental impairment due to polyI:C-induced innate immune activation of astrocytes

(2014) Shinnosuke Yamada et al.   BRAIN BEHAVIOR AND IMMUNITY

LRRK2 and neuroinflammation: partners in crime in Parkinson’s disease?

(2014) Isabella Russo et al.   Journal of Neuroinflammation

Interleukin 18 gene polymorphism is a risk factor for multiple sclerosis

(2014) Sevim Karakas Celik et al.   MOLECULAR BIOLOGY REPORTS

A2Aadenosine receptors and Parkinson's disease severity

(2013) I. Casetta et al.   ACTA NEUROLOGICA SCANDINAVICA

The secretome of mesenchymal stem cells: Potential implications for neuroregeneration

(2013) Gesine Paul et al.   BIOCHIMIE

Adenosine A2A Receptor Antagonists as Positron Emission Tomography (PET) Tracers

(2013) S. Khanapur et al.   CURRENT MEDICINAL CHEMISTRY

Neurotransmitters and Microglial-Mediated Neuroinflammation

(2013) Moonhee Lee   CURRENT PROTEIN & PEPTIDE SCIENCE

Non-dopaminergic Treatments for Motor Control in Parkinson’s Disease

(2013) Susan H. Fox   DRUGS

The NAD-dependent deacetylase sirtuin 2 is a suppressor of microglial activation and brain inflammation

(2013) Teresa Faria Pais et al.   EMBO JOURNAL

Multiple sclerosis lymphocytes upregulate A2Aadenosine receptors that are antiinflammatory when stimulated

(2013) Fabrizio Vincenzi et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

NADPH oxidase and aging drive microglial activation, oxidative stress, and dopaminergic neurodegeneration following systemic LPS administration

(2013) Liya Qin et al.   GLIA

MHCII Is Required for  -Synuclein-Induced Activation of Microglia, CD4 T Cell Proliferation, and Dopaminergic Neurodegeneration

(2013) A. S. Harms et al.   JOURNAL OF NEUROSCIENCE

MMP-3 Contributes to Nigrostriatal Dopaminergic Neuronal Loss, BBB Damage, and Neuroinflammation in an MPTP Mouse Model of Parkinson’s Disease

(2013) Young Cheul Chung et al.   MEDIATORS OF INFLAMMATION

Nod-Like Receptor Protein 1 Inflammasome Mediates Neuron Injury under High Glucose

(2013) Xian-Fang Meng et al.   MOLECULAR NEUROBIOLOGY

The NLRP3 Inflammasome in Alzheimer’s Disease

(2013) Meng-Shan Tan et al.   MOLECULAR NEUROBIOLOGY

Characterization of peripheral hematopoietic stem cells and monocytes in Parkinson's disease

(2013) Natalja Funk et al.   MOVEMENT DISORDERS

Parkinson's Disease and Alpha Synuclein: Is Parkinson's Disease a Prion-Like Disorder?

(2013) C. Warren Olanow et al.   MOVEMENT DISORDERS

The ubiquitin ligase parkin mediates resistance to intracellular pathogens

(2013) Paolo S. Manzanillo et al.   NATURE

Screening of Toll-Like Receptors Expression in Multiple System Atrophy Brains

(2013) Tomasz Brudek et al.   NEUROCHEMICAL RESEARCH

Polymorphisms in immune/inflammatory cytokine genes are related to Parkinson's disease with cognitive impairment in the Han Chinese population

(2013) Kun Nie et al.   NEUROSCIENCE LETTERS

Fine-Mapping, Gene Expression and Splicing Analysis of the Disease Associated LRRK2 Locus

(2013) Daniah Trabzuni et al.   PLoS One

Oligodendrocytes and the early multiple sclerosis lesion

(2012) John W. Prineas et al.   ANNALS OF NEUROLOGY

COX-2 in the neurodegenerative process of Parkinson's disease

(2012) Peter Teismann   BIOFACTORS

NLRP3 inflammasome activation in macrophage cell lines by prion protein fibrils as the source of IL-1β and neuronal toxicity

(2012) Iva Hafner-Bratkovič et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Novel Anti-Inflammatory and Neuroprotective Agents for Parkinsons Disease

(2012) Li Lu et al.   CNS & Neurological Disorders-Drug Targets

Inflammatory cytokines and NT-proCNP in Parkinson’s disease patients

(2012) Dariusz Koziorowski et al.   CYTOKINE

Infections as a risk factor for Parkinson's disease: a case–control study

(2012) Hristina Vlajinac et al.   INTERNATIONAL JOURNAL OF NEUROSCIENCE

DJ-1 regulates mast cell activation and IgE-mediated allergic responses

(2012) Do Kyun Kim et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Microglial Activation and Antioxidant Responses Induced by the Parkinson’s Disease Protein α-Synuclein

(2012) Dawn Béraud et al.   Journal of Neuroimmune Pharmacology

Reduced T helper and B lymphocytes in Parkinson's disease

(2012) Claire H. Stevens et al.   JOURNAL OF NEUROIMMUNOLOGY

Proteolytic activation of proapoptotic kinase protein kinase Cδ by tumor necrosis factor α death receptor signaling in dopaminergic neurons during neuroinflammation

(2012) Richard Gordon et al.   Journal of Neuroinflammation

Inflammation and α-Synuclein’s Prion-like Behavior in Parkinson's Disease—Is There a Link?

(2012) Carla M. Lema Tomé et al.   MOLECULAR NEUROBIOLOGY

I B  augments IL-12- and IL-18-mediated IFN-  production in human NK cells

(2011) Y. Kannan et al.   BLOOD

Interleukin-18 promoter polymorphisms and risk of Parkinson's disease in a Han Chinese population

(2011) Xiang Xu et al.   BRAIN RESEARCH

Toll-like receptors and macrophage activation in atherosclerosis

(2011) Anusha N. Seneviratne et al.   CLINICA CHIMICA ACTA

Adenosine and ATP Receptors in the Brain

(2011) Geoffrey Burnstock et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Leprosy susceptibility: genetic variations regulate innate and adaptive immunity, and disease outcome

(2011) Cynthia Chester Cardoso et al.   Future Microbiology

Effects of peripheral lymphocyte subpopulations and the clinical correlation with Parkinson's disease

(2011) Fumitoshi Niwa et al.   Geriatrics & Gerontology International

Use of ibuprofen and risk of Parkinson disease

(2011) X. Gao et al.   NEUROLOGY

Pathogenic LRRK2 Mutations Do Not Alter Gene Expression in Cell Model Systems or Human Brain Tissue

(2011) Michael J. Devine et al.   PLoS One

The Hedgehog Pathway Promotes Blood-Brain Barrier Integrity and CNS Immune Quiescence

(2011) J. I. Alvarez et al.   SCIENCE

IFN-γ Production Depends on IL-12 and IL-18 Combined Action and Mediates Host Resistance to Dengue Virus Infection in a Nitric Oxide-Dependent Manner

(2011) Caio T. Fagundes et al.   PLoS Neglected Tropical Diseases

Toll-like receptors in inflammatory bowel diseases: A decade later

(2010) Elke Cario   INFLAMMATORY BOWEL DISEASES

Effects of Hydrogen Sulfide-releasing l-DOPA Derivatives on Glial Activation

(2010) Moonhee Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inflammation in the Central Nervous System and Th17 Responses Are Inhibited by IFN- -Induced IL-18 Binding Protein

(2010) J. M. Millward et al.   JOURNAL OF IMMUNOLOGY

Regulatory T Cells Attenuate Th17 Cell-Mediated Nigrostriatal Dopaminergic Neurodegeneration in a Model of Parkinson’s Disease

(2010) Ashley D. Reynolds et al.   JOURNAL OF IMMUNOLOGY

Role of matrix metalloproteinase-3 in neurodegeneration

(2010) Eun-Mee Kim et al.   JOURNAL OF NEUROCHEMISTRY

The Toll-Like Receptor-3 Agonist Polyinosinic:Polycytidylic Acid Triggers Nigrostriatal Dopaminergic Degeneration

(2010) M. Deleidi et al.   JOURNAL OF NEUROSCIENCE

Delayed Dominant-Negative TNF Gene Therapy Halts Progressive Loss of Nigral Dopaminergic Neurons in a Rat Model of Parkinson's Disease

(2010) Ashley S Harms et al.   MOLECULAR THERAPY

Interleukin 18 Receptor 1 expression distinguishes patients with multiple sclerosis

(2010) Alan Gillett et al.   Multiple Sclerosis Journal

Common genetic variation in the HLA region is associated with late-onset sporadic Parkinson's disease

(2010) Taye H Hamza et al.   NATURE GENETICS

Innate and Adaptive Immunity for the Pathobiology of Parkinson's Disease

(2009) David K. Stone et al.   ANTIOXIDANTS & REDOX SIGNALING

Inhibition of Double-Stranded RNA-Induced Inducible Nitric Oxide Synthase Expression by Fraxinellone and Sauchinone in Murine Microglia

(2009) Chang Seok Lee et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

NSAID Use and the Risk of Parkinsonʼs Disease

(2009) Ali Samii et al.   DRUGS & AGING

Is There an Association between the Level of High-Sensitivity C-Reactive Protein and Idiopathic Parkinson’s Disease? A Comparison of Parkinson’s Disease Patients, Disease Controls and Healthy Individuals

(2009) In-Uk Song et al.   EUROPEAN NEUROLOGY

Mesenchymal stem cell transplantation attenuates blood brain barrier damage and neuroinflammation and protects dopaminergic neurons against MPTP toxicity in the substantia nigra in a model of Parkinson's disease

(2009) Yin Xia Chao et al.   JOURNAL OF NEUROIMMUNOLOGY

Characterization of the microglial phenotype under specific pro-inflammatory and anti-inflammatory conditions: Effects of oligomeric and fibrillar amyloid-β

(2009) Alessandro Michelucci et al.   JOURNAL OF NEUROIMMUNOLOGY

Peripheral Chemo-Cytokine Profiles in Alzheimers and Parkinsons Diseases

(2009) M. Reale et al.   MINI-REVIEWS IN MEDICINAL CHEMISTRY

Chronic expression of low levels of tumor necrosis factor-α in the substantia nigra elicits progressive neurodegeneration, delayed motor symptoms and microglia/macrophage activation

(2009) Ana Laura De Lella Ezcurra et al.   NEUROBIOLOGY OF DISEASE

T cell-microglial dialogue in Parkinson's disease and amyotrophic lateral sclerosis: are we listening?

(2009) Stanley H. Appel et al.   TRENDS IN IMMUNOLOGY

BioGPS: an extensible and customizable portal for querying and organizing gene annotation resources

(2009) Chunlei Wu et al.   GENOME BIOLOGY

Minocycline and neurodegenerative diseases

(2008) Hye-Sun Kim et al.   BEHAVIOURAL BRAIN RESEARCH

Central and systemic IL-1 exacerbates neurodegeneration and motor symptoms in a model of Parkinson's disease

(2008) M. C. Pott Godoy et al.   BRAIN

Toll-like receptors in the respiratory system: Their roles in inflammation

(2008) Chiaki Iwamura et al.   CURRENT ALLERGY AND ASTHMA REPORTS

The Blood-Central Nervous System Barriers Actively Control Immune Cell Entry into the Central Nervous System

(2008) Britta Engelhardt   CURRENT PHARMACEUTICAL DESIGN

Infiltration of CD4+ lymphocytes into the brain contributes to neurodegeneration in a mouse model of Parkinson disease

(2008) Vanessa Brochard et al.   JOURNAL OF CLINICAL INVESTIGATION

Non-steroidal anti-inflammatory drug use and the risk of Parkinson disease: A retrospective cohort study

(2008) Mahyar Etminan et al.   JOURNAL OF CLINICAL NEUROSCIENCE

Decreased blood–brain barrier P-glycoprotein function in the progression of Parkinson’s disease, PSP and MSA

(2008) A. L. Bartels et al.   JOURNAL OF NEURAL TRANSMISSION

Intranigral Lentiviral Delivery of Dominant-negative TNF Attenuates Neurodegeneration and Behavioral Deficits in Hemiparkinsonian rats

(2008) Melissa K McCoy et al.   MOLECULAR THERAPY

Correlation between DJ-1 levels in the cerebrospinal fluid and the progression of disabilities in multiple sclerosis patients

(2008) M Hirotani et al.   Multiple Sclerosis Journal

Serum interleukin (IL-2, IL-10, IL-6, IL-4), TNFα, and INFγ concentrations are elevated in patients with atypical and idiopathic parkinsonism

(2008) Bogdan Brodacki et al.   NEUROSCIENCE LETTERS

Inflammation as a causative factor in the aetiology of Parkinson's disease

(2007) P S Whitton   BRITISH JOURNAL OF PHARMACOLOGY