MMP-3 Contributes to Nigrostriatal Dopaminergic Neuronal Loss, BBB Damage, and Neuroinflammation in an MPTP Mouse Model of Parkinson’s Disease

Brain-resident microglia predominate over infiltrating myeloid cells in activation, phagocytosis and interaction with T-lymphocytes in the MPTP mouse model of Parkinson disease

(2012) Candan Depboylu et al.   EXPERIMENTAL NEUROLOGY

Matrix metalloproteinase-3 in the central nervous system: a look on the bright side

(2012) Inge Van Hove et al.   JOURNAL OF NEUROCHEMISTRY

Increased blood-cerebrospinal fluid transfer of albumin in advanced Parkinson’s disease

(2012) Valerio Pisani et al.   Journal of Neuroinflammation

Partial dopamine depletion in MPTP-treated mice differentially altered motor skill learning and action control

(2011) Laure Chagniel et al.   BEHAVIOURAL BRAIN RESEARCH

The role of neuroinflammation on the pathogenesis of Parkinson's disease

(2011) Young-Cheul Chung et al.   BMB Reports

A novel compound PTIQ protects the nigral dopaminergic neurones in an animal model of Parkinson's disease induced by MPTP

(2011) Hyo Jin Son et al.   BRITISH JOURNAL OF PHARMACOLOGY

Role of Matrix Metalloproteinase 3-mediated α-Synuclein Cleavage in Dopaminergic Cell Death

(2011) Dong-Hee Choi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cannabinoid Receptor Type 1 Protects Nigrostriatal Dopaminergic Neurons against MPTP Neurotoxicity by Inhibiting Microglial Activation

(2011) Y. C. Chung et al.   JOURNAL OF IMMUNOLOGY

Ethyl Pyruvate Rescues Nigrostriatal Dopaminergic Neurons by Regulating Glial Activation in a Mouse Model of Parkinson's Disease

(2011) S. H. Huh et al.   JOURNAL OF IMMUNOLOGY

An Aberrant Cerebellar Development in Mice Lacking Matrix Metalloproteinase-3

(2011) Inge Van Hove et al.   MOLECULAR NEUROBIOLOGY

Fluoxetine prevents MPTP-induced loss of dopaminergic neurons by inhibiting microglial activation

(2011) Young C. Chung et al.   NEUROPHARMACOLOGY

Matrix Metalloproteinase-3 Is Increased and Participates in Neuronal Apoptotic Signaling Downstream of Caspase-12 during Endoplasmic Reticulum Stress

(2010) Eun-Mee Kim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Paroxetine Prevents Loss of Nigrostriatal Dopaminergic Neurons by Inhibiting Brain Inflammation and Oxidative Stress in an Experimental Model of Parkinson's Disease

(2010) Y. C. Chung et al.   JOURNAL OF IMMUNOLOGY

Role of matrix metalloproteinase-3 in neurodegeneration

(2010) Eun-Mee Kim et al.   JOURNAL OF NEUROCHEMISTRY

Exendin-4 protects dopaminergic neurons by inhibition of microglial activation and matrix metalloproteinase-3 expression in an animal model of Parkinson's disease

(2009) Sehee Kim et al.   JOURNAL OF ENDOCRINOLOGY

Mesenchymal stem cell transplantation attenuates blood brain barrier damage and neuroinflammation and protects dopaminergic neurons against MPTP toxicity in the substantia nigra in a model of Parkinson's disease

(2009) Yin Xia Chao et al.   JOURNAL OF NEUROIMMUNOLOGY

Neuroinflammation in Parkinson's disease: a target for neuroprotection?

(2009) Etienne C Hirsch et al.   LANCET NEUROLOGY

Neuroinflammation in Parkinson's disease: Its role in neuronal death and implications for therapeutic intervention

(2009) Malú G. Tansey et al.   NEUROBIOLOGY OF DISEASE

Matrix metalloproteinase-3 contributes to vulnerability of the nigral dopaminergic neurons

(2009) Sung Tae Kim et al.   NEUROCHEMISTRY INTERNATIONAL

Doxycycline is Neuroprotective Against Nigral Dopaminergic Degeneration by a Dual Mechanism Involving MMP-3

(2009) Yuri Cho et al.   NEUROTOXICITY RESEARCH

Neuroprotective Effect of Ghrelin in the 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine Mouse Model of Parkinson’s Disease by Blocking Microglial Activation

(2009) Minho Moon et al.   NEUROTOXICITY RESEARCH

The blood-brain barrier in brain homeostasis and neurological diseases

(2008) Nicolas Weiss et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

CD4+ T cells mediate cytotoxicity in neurodegenerative diseases

(2008) Stanley H. Appel   JOURNAL OF CLINICAL INVESTIGATION

Infiltration of CD4+ lymphocytes into the brain contributes to neurodegeneration in a mouse model of Parkinson disease

(2008) Vanessa Brochard et al.   JOURNAL OF CLINICAL INVESTIGATION

Caffeine protects against MPTP-induced blood-brain barrier dysfunction in mouse striatum

(2008) Xuesong Chen et al.   JOURNAL OF NEUROCHEMISTRY

A novel intracellular role of matrix metalloproteinase-3 during apoptosis of dopaminergic cells

(2008) Dong Hee Choi et al.   JOURNAL OF NEUROCHEMISTRY

The Blood-Brain Barrier in Health and Chronic Neurodegenerative Disorders

(2008) Berislav V. Zlokovic   NEURON