Interplay of Matrix Stiffness and c-SRC in Hepatic Fibrosis

Novel insights into the function and dynamics of extracellular matrix in liver fibrosis

(2015) Morten A. Karsdal et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Janus-kinase-2 relates directly to portal hypertension and to complications in rodent and human cirrhosis

(2015) Sabine Klein et al.   GUT

SRC Family Kinase Inhibition Through a New Pyrazolo[3,4-d]Pyrimidine Derivative as a Feasible Approach for Glioblastoma Treatment

(2015) Elisa Ceccherini et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Src signaling pathways in prostate cancer

(2014) Andreas Varkaris et al.   CANCER AND METASTASIS REVIEWS

Angiotensin-II type 1 receptor-mediated Janus kinase 2 activation induces liver fibrosis

(2014) Michaela Granzow et al.   HEPATOLOGY

Circulating MicroRNAs as a marker for liver injury in human immunodeficiency virus patients

(2014) Evrim Anadol et al.   HEPATOLOGY

Identification and Validation of Src and Phospho-Src Family Proteins in Circulating Mononuclear Cells as Novel Biomarkers for Pancreatic Cancer

(2014) Kenji Yokoi et al.   Translational Oncology

Tissue mechanics and fibrosis

(2013) Rebecca G. Wells   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Physiological roles of Rho and Rho effectors in mammals

(2013) Dean Thumkeo et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Obeticholic acid, a farnesoid X receptor agonist, improves portal hypertension by two distinct pathways in cirrhotic rats

(2013) Len Verbeke et al.   HEPATOLOGY

The molecular rationale of Src inhibition in colorectal carcinomas

(2013) Antonios N. Gargalionis et al.   INTERNATIONAL JOURNAL OF CANCER

Fate tracing reveals hepatic stellate cells as dominant contributors to liver fibrosis independent of its aetiology

(2013) Ingmar Mederacke et al.   Nature Communications

The Roles of Hyaluronan/RHAMM/CD44 and Their Respective Interactions along the Insidious Pathways of Fibrosarcoma Progression

(2013) Dragana Nikitovic et al.   Biomed Research International

The endocannabinoid N-arachidonoyl dopamine (NADA) selectively induces oxidative stress-mediated cell death in hepatic stellate cells but not in hepatocytes

(2012) Alexandra Wojtalla et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Tyrosine kinase signaling in fibrotic disorders

(2012) Christian Beyer et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

An update on dual Src/Abl inhibitors

(2012) Francesca Musumeci et al.   Future Medicinal Chemistry

HSC-specific inhibition of Rho-kinase reduces portal pressure in cirrhotic rats without major systemic effects

(2012) Sabine Klein et al.   JOURNAL OF HEPATOLOGY

Hepatic and serum levels of miR-122 after chronic HCV-induced fibrosis

(2012) Jonel Trebicka et al.   JOURNAL OF HEPATOLOGY

Atorvastatin inhibits proliferation and apoptosis, but induces senescence in hepatic myofibroblasts and thereby attenuates hepatic fibrosis in rats

(2012) Sabine Klein et al.   LABORATORY INVESTIGATION

Hepatic stellate cells require a stiff environment for myofibroblastic differentiation

(2011) Abby L. Olsen et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Transglutaminase 2 null macrophages respond to lipopolysaccharide stimulation by elevated proinflammatory cytokine production due to an enhanced αvβ3 integrin-induced Src tyrosine kinase signaling

(2011) Zsolt Sarang et al.   IMMUNOLOGY LETTERS

Hepatocyte Growth Factor (HGF) Inhibits Collagen I and IV Synthesis in Hepatic Stellate Cells by miRNA-29 Induction

(2011) Monika Kwiecinski et al.   PLoS One

Atorvastatin attenuates hepatic fibrosis in rats after bile duct ligation via decreased turnover of hepatic stellate cells

(2010) Jonel Trebicka et al.   JOURNAL OF HEPATOLOGY

Adhesion signaling - crosstalk between integrins, Src and Rho

(2009) S. Huveneers et al.   JOURNAL OF CELL SCIENCE

The Formin-Homology Protein SmDia Interacts with the Src Kinase SmTK and the GTPase SmRho1 in the Gonads of Schistosoma mansoni

(2009) Thomas Quack et al.   PLoS One