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Inhibition of Janus kinase-2 signalling pathway ameliorates portal hypertensive syndrome in partial portal hypertensive and liver cirrhosis rats

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KLF2 exerts antifibrotic and vasoprotective effects in cirrhotic rat livers: behind the molecular mechanisms of statins

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Angiotensin-II type 1 receptor-mediated Janus kinase 2 activation induces liver fibrosis

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Activation of the Mas Receptor by Angiotensin-(1–7) in the Renin–Angiotensin System Mediates Mesenteric Vasodilatation in Cirrhosis

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Fate tracing reveals hepatic stellate cells as dominant contributors to liver fibrosis independent of its aetiology

(2013) Ingmar Mederacke et al.   Nature Communications

HSC-specific inhibition of Rho-kinase reduces portal pressure in cirrhotic rats without major systemic effects

(2012) Sabine Klein et al.   JOURNAL OF HEPATOLOGY

JAK2 the future: therapeutic strategies for JAK-dependent malignancies

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Atorvastatin attenuates hepatic fibrosis in rats after bile duct ligation via decreased turnover of hepatic stellate cells

(2010) Jonel Trebicka et al.   JOURNAL OF HEPATOLOGY

The Rho exchange factor Arhgef1 mediates the effects of angiotensin II on vascular tone and blood pressure

(2010) Christophe Guilluy et al.   NATURE MEDICINE

Safety and Efficacy of INCB018424, a JAK1 and JAK2 Inhibitor, in Myelofibrosis

(2010) Srdan Verstovsek et al.   NEW ENGLAND JOURNAL OF MEDICINE

Role of β3-adrenoceptors for intrahepatic resistance and portal hypertension in liver cirrhosis

(2009) Jonel Trebicka et al.   HEPATOLOGY

A novel model of CCl4-induced cirrhosis with ascites in the mouse

(2009) Marco Domenicali et al.   JOURNAL OF HEPATOLOGY

Novel aspects of the renin-angiotensin-aldosterone-system

(2008) Gunter Wolf   Frontiers in Bioscience-Landmark

Mechanisms of Hepatic Fibrogenesis

(2008) Scott L. Friedman   GASTROENTEROLOGY

Mechanisms of extrahepatic vasodilation in portal hypertension

(2008) M Hennenberg et al.   GUT