Obeticholic acid, a farnesoid X receptor agonist, improves portal hypertension by two distinct pathways in cirrhotic rats

Embolization of large spontaneous portosystemic shunts for refractory hepatic encephalopathy: A multicenter survey on safety and efficacy

(2013) Wim Laleman et al.   HEPATOLOGY

FXR Agonist INT-747 Upregulates DDAH Expression and Enhances Insulin Sensitivity in High-Salt Fed Dahl Rats

(2013) Yohannes T. Ghebremariam et al.   PLoS One

Farnesoid X receptor targeting to treat nonalcoholic steatohepatitis

(2012) Luciano Adorini et al.   DRUG DISCOVERY TODAY

Microparticles and Paracrine Signaling in Portal Hypertension: Crucial Conversations or Idle Chat?

(2012) Juan Carlos Garcia–Pagán et al.   GASTROENTEROLOGY

HSC-specific inhibition of Rho-kinase reduces portal pressure in cirrhotic rats without major systemic effects

(2012) Sabine Klein et al.   JOURNAL OF HEPATOLOGY

Functional aspects on the pathophysiology of portal hypertension in cirrhosis

(2012) Juan-Carlos García-Pagán et al.   JOURNAL OF HEPATOLOGY

Resveratrol improves intrahepatic endothelial dysfunction and reduces hepatic fibrosis and portal pressure in cirrhotic rats

(2012) Marco Di Pascoli et al.   JOURNAL OF HEPATOLOGY

Inhibition of eNOS phosphorylation mediates endothelial dysfunction in renal failure: new effect of asymmetric dimethylarginine

(2012) Hidemi Kajimoto et al.   KIDNEY INTERNATIONAL

Bile Acids Regulate Cardiovascular Function

(2011) Sandeep Khurana et al.   CTS-Clinical and Translational Science

Amelioration of portal hypertension and the hyperdynamic circulatory syndrome in cirrhotic rats by neuropeptide Y via pronounced splanchnic vasoaction

(2011) L. Moleda et al.   GUT

Farnesoid X receptor activation inhibits inflammation and preserves the intestinal barrier in inflammatory bowel disease

(2011) R. M. Gadaleta et al.   GUT

Critical illness evokes elevated circulating bile acids related to altered hepatic transporter and nuclear receptor expression

(2011) Yoo-Mee Vanwijngaerden et al.   HEPATOLOGY

Increased Activation of the Wnt/ -Catenin Pathway in Spontaneous Hepatocellular Carcinoma Observed in Farnesoid X Receptor Knockout Mice

(2011) A. Wolfe et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Meta-analysis: isosorbide-mononitrate alone or with either beta-blockers or endoscopic therapy for the management of oesophageal varices

(2010) L. L. Gluud et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Deleterious effects of beta-blockers on survival in patients with cirrhosis and refractory ascites

(2010) Thomas Sersté et al.   HEPATOLOGY

Revising consensus in portal hypertension: Report of the Baveno V consensus workshop on methodology of diagnosis and therapy in portal hypertension

(2010) Roberto de Franchis   JOURNAL OF HEPATOLOGY

Inhibition of Endothelin-1-Mediated Contraction of Hepatic Stellate Cells by FXR Ligand

(2010) Jiang Li et al.   PLoS One

Farnesoid X Receptor Critically Determines the Fibrotic Response in Mice but Is Expressed to a Low Extent in Human Hepatic Stellate Cells and Periductal Myofibroblasts

(2009) Peter Fickert et al.   AMERICAN JOURNAL OF PATHOLOGY

Clinical course of alcoholic liver cirrhosis: A Danish population-based cohort study

(2009) Peter Jepsen et al.   HEPATOLOGY

Farnesoid X receptor agonist WAY-362450 attenuates liver inflammation and fibrosis in murine model of non-alcoholic steatohepatitis

(2009) Songwen Zhang et al.   JOURNAL OF HEPATOLOGY

Role of Bile Acids and Bile Acid Receptors in Metabolic Regulation

(2009) Philippe Lefebvre et al.   PHYSIOLOGICAL REVIEWS

Superoxide dismutase gene transfer reduces portal pressure in CCl4 cirrhotic rats with portal hypertension

(2008) B Lavina et al.   GUT

Farnesoid X receptor antagonizes nuclear factor κB in hepatic inflammatory response

(2008) Yan-Dong Wang et al.   HEPATOLOGY

Farnesoid X Receptor Deficiency Induces Nonalcoholic Steatohepatitis in Low-Density Lipoprotein Receptor-Knockout Mice Fed a High-Fat Diet

(2008) B. Kong et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Analyzing real-time PCR data by the comparative CT method

(2008) Thomas D Schmittgen et al.   Nature Protocols