Atorvastatin inhibits proliferation and apoptosis, but induces senescence in hepatic myofibroblasts and thereby attenuates hepatic fibrosis in rats

Role of cannabinoid receptors in alcoholic hepatic injury: steatosis and fibrogenesis are increased in CB2 receptor-deficient mice and decreased in CB1 receptor knockouts

(2011) Jonel Trebicka et al.   LIVER INTERNATIONAL

Wnt/β-Catenin Signaling Induces the Aging of Mesenchymal Stem Cells through the DNA Damage Response and the p53/p21 Pathway

(2011) Da-yong Zhang et al.   PLoS One

The essence of senescence

(2010) T. Kuilman et al.   GENES & DEVELOPMENT

Atorvastatin attenuates hepatic fibrosis in rats after bile duct ligation via decreased turnover of hepatic stellate cells

(2010) Jonel Trebicka et al.   JOURNAL OF HEPATOLOGY

Atorvastatin induces apoptosis by a caspase-9-dependent pathway: an in vitro study on activated rat hepatic stellate cells

(2010) Isabella Aprigliano et al.   LIVER INTERNATIONAL

Simvastatin Lowers Portal Pressure in Patients With Cirrhosis and Portal Hypertension: A Randomized Controlled Trial

(2009) Juan G. Abraldes et al.   GASTROENTEROLOGY

Senescence of activated stellate cells: Not just early retirement

(2009) Jörg Schrader et al.   HEPATOLOGY

Protocols to detect senescence-associated beta-galactosidase (SA-βgal) activity, a biomarker of senescent cells in culture and in vivo

(2009) Florence Debacq-Chainiaux et al.   Nature Protocols

Senescence: Not Just for Tumor Suppression

(2008) Michael R. Green   CELL

Senescence of Activated Stellate Cells Limits Liver Fibrosis

(2008) Valery Krizhanovsky et al.   CELL

Mechanisms of Hepatic Fibrogenesis

(2008) Scott L. Friedman   GASTROENTEROLOGY

Adenosine induces loss of actin stress fibers and inhibits contraction in hepatic stellate cells via Rho inhibition

(2008) Muhammad A. Sohail et al.   HEPATOLOGY

Myofibroblast – like cells and liver fibrogenesis: Emerging concepts in a rapidly moving scenario

(2007) Maurizio Parola et al.   MOLECULAR ASPECTS OF MEDICINE