Inhibition of the processing of miR-25 by HIPK2-Phosphorylated-MeCP2 induces NOX4 in early diabetic nephropathy

MicroRNAs in Diabetic Nephropathy: From Biomarkers to Therapy

(2016) Kate Simpson et al.   Current Diabetes Reports

Targeting non-coding RNA for the therapy of renal disease

(2016) Laura Denby et al.   CURRENT OPINION IN PHARMACOLOGY

An endoplasmic reticulum stress-regulated lncRNA hosting a microRNA megacluster induces early features of diabetic nephropathy

(2016) Mitsuo Kato et al.   Nature Communications

MicroRNAs in diabetic nephropathy: functions, biomarkers, and therapeutic targets

(2015) Mitsuo Kato et al.   Annals of the New York Academy of Sciences

Podocyte-specific Nox4 deletion affords renoprotection in a mouse model of diabetic nephropathy

(2015) Jay C. Jha et al.   DIABETOLOGIA

Transcription Factor Hepatocyte Nuclear Factor-1β (HNF-1β) Regulates MicroRNA-200 Expression through a Long Noncoding RNA

(2015) Sachin S. Hajarnis et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Metabolomics Reveals a Key Role for Fumarate in Mediating the Effects of NADPH Oxidase 4 in Diabetic Kidney Disease

(2015) Y.-H. You et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

MicroRNAs in renal fibrosis

(2015) Arthur C.-K. Chung et al.   Frontiers in Physiology

New Insights Into Molecular Mechanisms of Diabetic Kidney Disease

(2014) Shawn S. Badal et al.   AMERICAN JOURNAL OF KIDNEY DISEASES

MeCP2 Suppresses Nuclear MicroRNA Processing and Dendritic Growth by Regulating the DGCR8/Drosha Complex

(2014) Tian-Lin Cheng et al.   DEVELOPMENTAL CELL

MeCP2 Caught Moonlighting as a Suppressor of MicroRNA Processing

(2014) Jae-Sung Woo et al.   DEVELOPMENTAL CELL

Transforming Growth Factor β1 (TGF-β1) Enhances Expression of Profibrotic Genes through a Novel Signaling Cascade and MicroRNAs in Renal Mesangial Cells

(2014) Nancy E. Castro et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Molecular mechanisms of diabetic kidney disease

(2014) Kimberly Reidy et al.   JOURNAL OF CLINICAL INVESTIGATION

Genetic Targeting or Pharmacologic Inhibition of NADPH Oxidase Nox4 Provides Renoprotection in Long-Term Diabetic Nephropathy

(2014) J. C. Jha et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Inhibition of miR-25 improves cardiac contractility in the failing heart

(2014) Christine Wahlquist et al.   NATURE

Regulation of microRNA biogenesis

(2014) Minju Ha et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Diabetic nephropathy—emerging epigenetic mechanisms

(2014) Mitsuo Kato et al.   Nature Reviews Nephrology

MicroRNAs in kidney physiology and disease

(2014) Piera Trionfini et al.   Nature Reviews Nephrology

MeCP2 post-translational modifications: a mechanism to control its involvement in synaptic plasticity and homeostasis?

(2014) Elisa Bellini et al.   Frontiers in Cellular Neuroscience

Nox4 and diabetic nephropathy: With a friend like this, who needs enemies?

(2013) Yves Gorin et al.   FREE RADICAL BIOLOGY AND MEDICINE

FOG2 Protein Down-regulation by Transforming Growth Factor-β1-induced MicroRNA-200b/c Leads to Akt Kinase Activation and Glomerular Mesangial Hypertrophy Related to Diabetic Nephropathy

(2013) Jung Tak Park et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lipoxins Attenuate Renal Fibrosis by Inducing let-7c and Suppressing TGF R1

(2013) E. P. Brennan et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Transforming growth factor-β1-mediated renal fibrosis is dependent on the regulation of transforming growth factor receptor 1 expression by let-7b

(2013) Bo Wang et al.   KIDNEY INTERNATIONAL

MicroRNA-29b Inhibits Diabetic Nephropathy in db/db Mice

(2013) Hai-Yong Chen et al.   MOLECULAR THERAPY

miR-25 and miR-92a regulate insulin I biosynthesis in rats

(2013) Dwi Setyowati Karolina et al.   RNA Biology

TGF-  Induces Acetylation of Chromatin and of Ets-1 to Alleviate Repression of miR-192 in Diabetic Nephropathy

(2013) M. Kato et al.   Science Signaling

A systems approach identifies HIPK2 as a key regulator of kidney fibrosis

(2012) Yuanmeng Jin et al.   NATURE MEDICINE

The Role of MeCP2 in the Brain

(2011) Jacky Guy et al.   Annual Review of Cell and Developmental Biology

A Glimpse of Various Pathogenetic Mechanisms of Diabetic Nephropathy

(2011) Yashpal S. Kanwar et al.   Annual Review of Pathology-Mechanisms of Disease

From top to bottom: The two faces of HIPK2 for regulation of the hypoxic response

(2011) Marco A. Calzado et al.   CELL CYCLE

MicroRNA-451 regulates p38 MAPK signaling by targeting of Ywhaz and suppresses the mesangial hypertrophy in early diabetic nephropathy

(2011) Zheng Zhang et al.   FEBS LETTERS

MicroRNA-21 Orchestrates High Glucose-induced Signals to TOR Complex 1, Resulting in Renal Cell Pathology in Diabetes

(2011) Nirmalya Dey et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Suppression of microRNA-29 Expression by TGF- 1 Promotes Collagen Expression and Renal Fibrosis

(2011) B. Wang et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

A microRNA circuit mediates transforming growth factor-β1 autoregulation in renal glomerular mesangial cells

(2011) Mitsuo Kato et al.   KIDNEY INTERNATIONAL

Regulation of NADPH Oxidase Activity Is Associated with miRNA-25-Mediated NOX4 Expression in Experimental Diabetic Nephropathy

(2010) Yibing Fu et al.   AMERICAN JOURNAL OF NEPHROLOGY

High glucose down-regulates miR-29a to increase collagen IV production in HK-2 cells

(2010) Bin Du et al.   FEBS LETTERS

Identification of MicroRNA-93 as a Novel Regulator of Vascular Endothelial Growth Factor in Hyperglycemic Conditions

(2010) Jianyin Long et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

miR-192 Mediates TGF- /Smad3-Driven Renal Fibrosis

(2010) A. C. K. Chung et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

MicroRNA control of signal transduction

(2010) Masafumi Inui et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

MicroRNAs: Target Recognition and Regulatory Functions

(2009) David P. Bartel   CELL

Methyl-CpG-binding protein 2 is phosphorylated by homeodomain-interacting protein kinase 2 and contributes to apoptosis

(2009) Giorgia Bracaglia et al.   EMBO REPORTS

MicroRNA-21 protects from mesangial cell proliferation induced by diabetic nephropathy in db/db mice

(2009) Zheng Zhang et al.   FEBS LETTERS

The miR-106b-25 Polycistron, Activated by Genomic Amplification, Functions as an Oncogene by Suppressing p21 and Bim

(2009) Takatsugu Kan et al.   GASTROENTEROLOGY

TGF-β activates Akt kinase through a microRNA-dependent amplifying circuit targeting PTEN

(2009) Mitsuo Kato et al.   NATURE CELL BIOLOGY

Emerging Role of miR-106b-25/miR-17-92 Clusters in the Control of Transforming Growth Factor   Signaling

(2008) F. Petrocca et al.   CANCER RESEARCH

Control of HIPK2 stability by ubiquitin ligase Siah-1 and checkpoint kinases ATM and ATR

(2008) Melanie Winter et al.   NATURE CELL BIOLOGY