TGF-  Induces Acetylation of Chromatin and of Ets-1 to Alleviate Repression of miR-192 in Diabetic Nephropathy

Transforming growth factor β1 represses proximal tubular cell microRNA-192 expression through decreased hepatocyte nuclear factor DNA binding

(2012) Robert H. Jenkins et al.   BIOCHEMICAL JOURNAL

MicroRNAs and the glomerulus

(2012) Mitsuo Kato et al.   EXPERIMENTAL CELL RESEARCH

Inhibiting MicroRNA-192 Ameliorates Renal Fibrosis in Diabetic Nephropathy

(2012) S. Putta et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Akt-Mediated Regulation of Autophagy and Tumorigenesis Through Beclin 1 Phosphorylation

(2012) R. C. Wang et al.   SCIENCE

Next-generation Akt inhibitors provide greater specificity: effects on glucose metabolism in adipocytes

(2011) Shixiong Tan et al.   BIOCHEMICAL JOURNAL

Master Transcription Factors Determine Cell-Type-Specific Responses to TGF-β Signaling

(2011) Alan C. Mullen et al.   CELL

MicroRNA-29c Is a Signature MicroRNA under High Glucose Conditions That Targets Sprouty Homolog 1, and Itsin VivoKnockdown Prevents Progression of Diabetic Nephropathy

(2011) Jianyin Long et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

p53 regulates epithelial–mesenchymal transition through microRNAs targeting ZEB1 and ZEB2

(2011) Taewan Kim et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Low-dose paclitaxel ameliorates fibrosis in the remnant kidney model by down-regulating miR-192

(2011) Lin Sun et al.   JOURNAL OF PATHOLOGY

The complex world of kidney microRNAs

(2011) Balakuntalam S. Kasinath et al.   KIDNEY INTERNATIONAL

A microRNA circuit mediates transforming growth factor-β1 autoregulation in renal glomerular mesangial cells

(2011) Mitsuo Kato et al.   KIDNEY INTERNATIONAL

MicroRNAs as mediators and therapeutic targets in chronic kidney disease

(2011) Johan M. Lorenzen et al.   Nature Reviews Nephrology

Downregulation of p53-inducible microRNAs 192, 194, and 215 Impairs the p53/MDM2 Autoregulatory Loop in Multiple Myeloma Development

(2010) Flavia Pichiorri et al.   CANCER CELL

E-Cadherin Expression Is Regulated by miR-192/215 by a Mechanism That Is Independent of the Profibrotic Effects of Transforming Growth Factor- 

(2010) B. Wang et al.   DIABETES

Diabetic Nephropathy Is Accelerated by Farnesoid X Receptor Deficiency and Inhibited by Farnesoid X Receptor Activation in a Type 1 Diabetes Model

(2010) X. X. Wang et al.   DIABETES

Genome-wide analysis of ETS-family DNA-binding in vitro and in vivo

(2010) Gong-Hong Wei et al.   EMBO JOURNAL

Post-transcriptional Up-regulation of Tsc-22 by Ybx1, a Target of miR-216a, Mediates TGF-β-induced Collagen Expression in Kidney Cells

(2010) Mitsuo Kato et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Loss of MicroRNA-192 Promotes Fibrogenesis in Diabetic Nephropathy

(2010) A. Krupa et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

miR-192 Mediates TGF- /Smad3-Driven Renal Fibrosis

(2010) A. C. K. Chung et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

MK-2206, an Allosteric Akt Inhibitor, Enhances Antitumor Efficacy by Standard Chemotherapeutic Agents or Molecular Targeted Drugs In vitro and In vivo

(2010) H. Hirai et al.   MOLECULAR CANCER THERAPEUTICS

Intrarenal Expression of miRNAs in Patients With Hypertensive Nephrosclerosis

(2009) G. Wang et al.   AMERICAN JOURNAL OF HYPERTENSION

Cellular context-dependent “colors” of transforming growth factor-β signaling

(2009) Hiroaki Ikushima et al.   CANCER SCIENCE

Conserved MicroRNA miR-8/miR-200 and Its Target USH/FOG2 Control Growth by Regulating PI3K

(2009) Seogang Hyun et al.   CELL

A Mutant-p53/Smad Complex Opposes p63 to Empower TGFβ-Induced Metastasis

(2009) Maddalena Adorno et al.   CELL

Intrarenal expression of microRNAs in patients with IgA nephropathy

(2009) Gang Wang et al.   LABORATORY INVESTIGATION

TGF-β activates Akt kinase through a microRNA-dependent amplifying circuit targeting PTEN

(2009) Mitsuo Kato et al.   NATURE CELL BIOLOGY

Coordinated Regulation of Cell Cycle Transcripts by p53-Inducible microRNAs, miR-192 and miR-215

(2008) S. A. Georges et al.   CANCER RESEARCH

p53-Responsive MicroRNAs 192 and 215 Are Capable of Inducing Cell Cycle Arrest

(2008) C. J. Braun et al.   CANCER RESEARCH

MicroRNA-377 is up-regulated and can lead to increased fibronectin production in diabetic nephropathy

(2008) Qiang Wang et al.   FASEB JOURNAL

MicroRNA-155 Is Regulated by the Transforming Growth Factor  /Smad Pathway and Contributes to Epithelial Cell Plasticity by Targeting RhoA

(2008) W. Kong et al.   MOLECULAR AND CELLULAR BIOLOGY

Chromatin Immunoprecipitation on Microarray Analysis of Smad2/3 Binding Sites Reveals Roles of ETS1 and TFAP2A in Transforming Growth Factor   Signaling

(2008) D. Koinuma et al.   MOLECULAR AND CELLULAR BIOLOGY

Inducible expression of microRNA-194 is regulated by HNF-1  during intestinal epithelial cell differentiation

(2008) K. Hino et al.   RNA