Diabetic nephropathy—emerging epigenetic mechanisms

miR-192 Induces G2/M Growth Arrest in Aristolochic Acid Nephropathy

(2014) Robert H. Jenkins et al.   AMERICAN JOURNAL OF PATHOLOGY

Evaluating the Role of Epigenetic Histone Modifications in the Metabolic Memory of Type 1 Diabetes

(2014) Feng Miao et al.   DIABETES

Identification of Novel Long Noncoding RNAs Associated with TGF-β/Smad3-Mediated Renal Inflammation and Fibrosis by RNA Sequencing

(2013) Qin Zhou et al.   AMERICAN JOURNAL OF PATHOLOGY

Effect of miR-21 on Renal Fibrosis by Regulating MMP-9 and TIMP1 in kk-ay Diabetic Nephropathy Mice

(2013) Jinyang Wang et al.   CELL BIOCHEMISTRY AND BIOPHYSICS

Novel Long Noncoding RNAs Are Regulated by Angiotensin II in Vascular Smooth Muscle Cells

(2013) Amy Leung et al.   CIRCULATION RESEARCH

Urinary sediment miRNA levels in adult nephrotic syndrome

(2013) Gang Wang et al.   CLINICA CHIMICA ACTA

Emerging Roles for miRNAs in the Development, Diagnosis, and Treatment of Diabetic Nephropathy

(2013) Johanna K. DiStefano et al.   Current Diabetes Reports

Pericytes in kidney fibrosis

(2013) Shuyu Ren et al.   CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION

Transforming Growth Factor-β–Induced Cross Talk Between p53 and a MicroRNA in the Pathogenesis of Diabetic Nephropathy

(2013) Supriya D. Deshpande et al.   DIABETES

Kidney Disease and Related Findings in the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications Study

(2013) Ian H. de Boer et al.   DIABETES CARE

Fractalkine and its receptor mediate extracellular matrix accumulation in diabetic nephropathy in mice

(2013) K. H. Song et al.   DIABETOLOGIA

miR-21 is a key therapeutic target for renal injury in a mouse model of type 2 diabetes

(2013) X. Zhong et al.   DIABETOLOGIA

Micro-RNA Expression in the Urinary Sediment of Patients with Chronic Kidney Diseases

(2013) Cheuk-Chun Szeto et al.   DISEASE MARKERS

Urinary Biomarkers for The Prediction of Reversibility in Acute-on-Chronic Renal Failure

(2013) Cathy Choi-Wan Luk et al.   DISEASE MARKERS

Sirt1 resists advanced glycation end products-induced expressions of fibronectin and TGF-β1 by activating the Nrf2/ARE pathway in glomerular mesangial cells

(2013) Kaipeng Huang et al.   FREE RADICAL BIOLOGY AND MEDICINE

MicroRNAs: potential mediators and biomarkers of diabetic complications

(2013) Mitsuo Kato et al.   FREE RADICAL BIOLOGY AND MEDICINE

Aldose reductase regulates miR-200a-3p/141-3p to coordinate Keap1–Nrf2, Tgfβ1/2, and Zeb1/2 signaling in renal mesangial cells and the renal cortex of diabetic mice

(2013) Jie Wei et al.   FREE RADICAL BIOLOGY AND MEDICINE

FOG2 Protein Down-regulation by Transforming Growth Factor-β1-induced MicroRNA-200b/c Leads to Akt Kinase Activation and Glomerular Mesangial Hypertrophy Related to Diabetic Nephropathy

(2013) Jung Tak Park et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MicroRNA-22 Is a Master Regulator of Bone Morphogenetic Protein-7/6 Homeostasis in the Kidney

(2013) Jianyin Long et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lipoxins Attenuate Renal Fibrosis by Inducing let-7c and Suppressing TGF R1

(2013) E. P. Brennan et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Downregulation of MicroRNA-30 Facilitates Podocyte Injury and Is Prevented by Glucocorticoids

(2013) J. Wu et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Histone Deacetylase Inhibitor Enhances Recovery after AKI

(2013) C. Cianciolo Cosentino et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

The microRNA miR-433 promotes renal fibrosis by amplifying the TGF-β/Smad3-Azin1 pathway

(2013) Rong Li et al.   KIDNEY INTERNATIONAL

Losartan reverses permissive epigenetic changes in renal glomeruli of diabetic db/db mice

(2013) Marpadga A. Reddy et al.   KIDNEY INTERNATIONAL

Transforming growth factor-β1-mediated renal fibrosis is dependent on the regulation of transforming growth factor receptor 1 expression by let-7b

(2013) Bo Wang et al.   KIDNEY INTERNATIONAL

Epigenetic changes in renal genes dysregulated in mouse and rat models of type 1 diabetes

(2013) Radko Komers et al.   LABORATORY INVESTIGATION

Urine miRNAs: Potential biomarkers for monitoring progression of early stages of diabetic nephropathy

(2013) Yeyi Yang et al.   MEDICAL HYPOTHESES

MicroRNA-29b Inhibits Diabetic Nephropathy in db/db Mice

(2013) Hai-Yong Chen et al.   MOLECULAR THERAPY

Identification of human epididymis protein-4 as a fibroblast-derived mediator of fibrosis

(2013) Valerie S LeBleu et al.   NATURE MEDICINE

Targeting long non-coding RNA to therapeutically upregulate gene expression

(2013) Claes Wahlestedt   NATURE REVIEWS DRUG DISCOVERY

Serum microRNAs levels in primary focal segmental glomerulosclerosis

(2013) Xiaoyi Cai et al.   PEDIATRIC NEPHROLOGY

Functional Implications of MicroRNA-215 in TGF-β1-Induced Phenotypic Transition of Mesangial Cells by Targeting CTNNBIP1

(2013) Jiao Mu et al.   PLoS One

Urinary MicroRNA Profiling in the Nephropathy of Type 1 Diabetes

(2013) Christos Argyropoulos et al.   PLoS One

Urinary Exosomal MicroRNAs in Incipient Diabetic Nephropathy

(2013) Federica Barutta et al.   PLoS One

Role of MicroRNA 1207-5P and Its Host Gene, the Long Non-Coding RNA Pvt1, as Mediators of Extracellular Matrix Accumulation in the Kidney: Implications for Diabetic Nephropathy

(2013) M. Lucrecia Alvarez et al.   PLoS One

TGF-  Induces Acetylation of Chromatin and of Ets-1 to Alleviate Repression of miR-192 in Diabetic Nephropathy

(2013) M. Kato et al.   Science Signaling

Epigenetic Modifications in the Pathogenesis of Diabetic Nephropathy

(2013) Marpadga A. Reddy et al.   SEMINARS IN NEPHROLOGY

Cytosine methylation changes in enhancer regions of core pro-fibrotic genes characterize kidney fibrosis development

(2013) Yi-An Ko et al.   GENOME BIOLOGY

Towards understanding the inherited susceptibility for nephropathy in diabetes

(2012) Merlin C. Thomas et al.   CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION

The Akt-FoxO3a-manganese superoxide dismutase pathway is involved in the regulation of oxidative stress in diabetic nephropathy

(2012) Qian Lu et al.   EXPERIMENTAL PHYSIOLOGY

Role of Nox4 in murine models of kidney disease

(2012) Andrea Babelova et al.   FREE RADICAL BIOLOGY AND MEDICINE

MS2 VLP-based delivery of microRNA-146a inhibits autoantibody production in lupus-prone mice

(2012) Yang Pan et al.   International Journal of Nanomedicine

Profiles of Epigenetic Histone Post-translational Modifications at Type 1 Diabetes Susceptible Genes

(2012) Feng Miao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Discovering the first microRNA-targeted drug

(2012) Morten Lindow et al.   JOURNAL OF CELL BIOLOGY

Circulating TNF Receptors 1 and 2 Predict Stage 3 CKD in Type 1 Diabetes

(2012) T. Gohda et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Inhibiting MicroRNA-192 Ameliorates Renal Fibrosis in Diabetic Nephropathy

(2012) S. Putta et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Modular regulatory principles of large non-coding RNAs

(2012) Mitchell Guttman et al.   NATURE

An integrated encyclopedia of DNA elements in the human genome

(2012)   NATURE

Using formaldehyde-assisted isolation of regulatory elements (FAIRE) to isolate active regulatory DNA

(2012) Jeremy M Simon et al.   Nature Protocols

Functions of DNA methylation: islands, start sites, gene bodies and beyond

(2012) Peter A. Jones   NATURE REVIEWS GENETICS

Emerging functional and mechanistic paradigms of mammalian long non-coding RNAs

(2012) V. A. Moran et al.   NUCLEIC ACIDS RESEARCH

Downregulation of miR-205 Modulates Cell Susceptibility to Oxidative and Endoplasmic Reticulum Stresses in Renal Tubular Cells

(2012) Shiyo Muratsu-Ikeda et al.   PLoS One

Systematic Localization of Common Disease-Associated Variation in Regulatory DNA

(2012) M. T. Maurano et al.   SCIENCE

MicroRNA-21 Promotes Fibrosis of the Kidney by Silencing Metabolic Pathways

(2012) B. N. Chau et al.   Science Translational Medicine

MicroRNA Circuits in Transforming Growth Factor-β Actions and Diabetic Nephropathy

(2012) Mitsuo Kato et al.   SEMINARS IN NEPHROLOGY

Perspectives on Systems Biology Applications in Diabetic Kidney Disease

(2012) Claudiu V. Komorowsky et al.   Journal of Cardiovascular Translational Research

Oxidative Stress, Nox Isoforms and Complications of Diabetes—Potential Targets for Novel Therapies

(2012) Mona Sedeek et al.   Journal of Cardiovascular Translational Research

New Susceptibility Loci Associated with Kidney Disease in Type 1 Diabetes

(2012) Niina Sandholm et al.   PLoS Genetics

An encyclopedia of mouse DNA elements (Mouse ENCODE)

(2012) et al.   GENOME BIOLOGY

Long-Term Administration of the Histone Deacetylase Inhibitor Vorinostat Attenuates Renal Injury in Experimental Diabetes through an Endothelial Nitric Oxide Synthase-Dependent Mechanism

(2011) Andrew Advani et al.   AMERICAN JOURNAL OF PATHOLOGY

A Glimpse of Various Pathogenetic Mechanisms of Diabetic Nephropathy

(2011) Yashpal S. Kanwar et al.   Annual Review of Pathology-Mechanisms of Disease

Epigenetics: deciphering its role in diabetes and its chronic complications

(2011) Louisa M Villeneuve et al.   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

miR-146a–Mediated Extracellular Matrix Protein Production in Chronic Diabetes Complications

(2011) Biao Feng et al.   DIABETES

Transcriptome Analysis of Human Diabetic Kidney Disease

(2011) K. I. Woroniecka et al.   DIABETES

DNA methylation profiling identifies epigenetic differences between diabetes patients with ESRD and diabetes patients without nephropathy

(2011) Carmen Sapienza et al.   Epigenetics

MicroRNA-451 regulates p38 MAPK signaling by targeting of Ywhaz and suppresses the mesangial hypertrophy in early diabetic nephropathy

(2011) Zheng Zhang et al.   FEBS LETTERS

Integrative annotation of human large intergenic noncoding RNAs reveals global properties and specific subclasses

(2011) M. N. Cabili et al.   GENES & DEVELOPMENT

Genome-wide analysis distinguishes hyperglycemia regulated epigenetic signatures of primary vascular cells

(2011) L. Pirola et al.   GENOME RESEARCH

Genome-wide survey reveals predisposing diabetes type 2-related DNA methylation variations in human peripheral blood

(2011) Gidon Toperoff et al.   HUMAN MOLECULAR GENETICS

MicroRNA-29c Is a Signature MicroRNA under High Glucose Conditions That Targets Sprouty Homolog 1, and Itsin VivoKnockdown Prevents Progression of Diabetic Nephropathy

(2011) Jianyin Long et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MicroRNA-21 Orchestrates High Glucose-induced Signals to TOR Complex 1, Resulting in Renal Cell Pathology in Diabetes

(2011) Nirmalya Dey et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Epithelial-mesenchymal transition (EMT) in kidney fibrosis: fact or fantasy?

(2011) Wilhelm Kriz et al.   JOURNAL OF CLINICAL INVESTIGATION

Low-dose paclitaxel ameliorates fibrosis in the remnant kidney model by down-regulating miR-192

(2011) Lin Sun et al.   JOURNAL OF PATHOLOGY

The Pro-Apoptotic Protein Bim Is a MicroRNA Target in Kidney Progenitors

(2011) J. Ho et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

TGF- /Smad3 Signaling Promotes Renal Fibrosis by Inhibiting miR-29

(2011) W. Qin et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Macrophages in Renal Disease

(2011) Y. Wang et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Suppression of microRNA-29 Expression by TGF- 1 Promotes Collagen Expression and Renal Fibrosis

(2011) B. Wang et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

A microRNA circuit mediates transforming growth factor-β1 autoregulation in renal glomerular mesangial cells

(2011) Mitsuo Kato et al.   KIDNEY INTERNATIONAL

Biomarkers in chronic kidney disease: a review

(2011) Robert G. Fassett et al.   KIDNEY INTERNATIONAL

The inducible deletion of Drosha and microRNAs in mature podocytes results in a collapsing glomerulopathy

(2011) Olga Zhdanova et al.   KIDNEY INTERNATIONAL

Altered expression of microRNA miR-146a correlates with the development of chronic renal inflammation

(2011) Osamu Ichii et al.   KIDNEY INTERNATIONAL

Inflammatory molecules and pathways in the pathogenesis of diabetic nephropathy

(2011) Juan F. Navarro-González et al.   Nature Reviews Nephrology

Circulating microRNA expression is reduced in chronic kidney disease

(2011) Calida S. Neal et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Intensive Diabetes Therapy and Glomerular Filtration Rate in Type 1 Diabetes

(2011)   NEW ENGLAND JOURNAL OF MEDICINE

ENCODE whole-genome data in the UCSC Genome Browser: update 2012

(2011) K. R. Rosenbloom et al.   NUCLEIC ACIDS RESEARCH

Functional Characterization of the Plasmacytoma Variant Translocation 1 Gene (PVT1) in Diabetic Nephropathy

(2011) M. Lucrecia Alvarez et al.   PLoS One

Long noncoding RNAs and human disease

(2011) Orly Wapinski et al.   TRENDS IN CELL BIOLOGY

Interleukin-18 contributes more closely to the progression of diabetic nephropathy than other diabetic complications

(2010) Takayuki Fujita et al.   ACTA DIABETOLOGICA

Regulation of NADPH Oxidase Activity Is Associated with miRNA-25-Mediated NOX4 Expression in Experimental Diabetic Nephropathy

(2010) Yibing Fu et al.   AMERICAN JOURNAL OF NEPHROLOGY

Genome-wide DNA methylation analysis for diabetic nephropathy in type 1 diabetes mellitus

(2010) Christopher G Bell et al.   BMC Medical Genomics

Epigenetics

(2010) Mark E. Cooper et al.   CIRCULATION RESEARCH

MiR423-5p As a Circulating Biomarker for Heart Failure

(2010) Anke J. Tijsen et al.   CIRCULATION RESEARCH

Oxidative Stress and Diabetic Complications

(2010) Ferdinando Giacco et al.   CIRCULATION RESEARCH

E-Cadherin Expression Is Regulated by miR-192/215 by a Mechanism That Is Independent of the Profibrotic Effects of Transforming Growth Factor- 

(2010) B. Wang et al.   DIABETES

miR-200a Prevents Renal Fibrogenesis Through Repression of TGF- 2 Expression

(2010) B. Wang et al.   DIABETES

Diabetic Nephropathy Is Accelerated by Farnesoid X Receptor Deficiency and Inhibited by Farnesoid X Receptor Activation in a Type 1 Diabetes Model

(2010) X. X. Wang et al.   DIABETES

Enhanced Levels of microRNA-125b in Vascular Smooth Muscle Cells of Diabetic db/db Mice Lead to Increased Inflammatory Gene Expression by Targeting the Histone Methyltransferase Suv39h1

(2010) L. M. Villeneuve et al.   DIABETES

miRNAs as molecular biomarkers of cancer

(2010) Muller Fabbri   EXPERT REVIEW OF MOLECULAR DIAGNOSTICS

High glucose down-regulates miR-29a to increase collagen IV production in HK-2 cells

(2010) Bin Du et al.   FEBS LETTERS

Identification of MicroRNA-93 as a Novel Regulator of Vascular Endothelial Growth Factor in Hyperglycemic Conditions

(2010) Jianyin Long et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Post-transcriptional Up-regulation of Tsc-22 by Ybx1, a Target of miR-216a, Mediates TGF-β-induced Collagen Expression in Kidney Cells

(2010) Mitsuo Kato et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Epigenetic regulation of high glucose-induced proinflammatory cytokine production in monocytes by curcumin

(2010) Jung-Mi Yun et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

miRNAs in human cancer

(2010) Thalia A Farazi et al.   JOURNAL OF PATHOLOGY

Loss of MicroRNA-192 Promotes Fibrogenesis in Diabetic Nephropathy

(2010) A. Krupa et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Epigenetic Histone Methylation Modulates Fibrotic Gene Expression

(2010) G. Sun et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

miR-192 Mediates TGF- /Smad3-Driven Renal Fibrosis

(2010) A. C. K. Chung et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Dicer regulates the development of nephrogenic and ureteric compartments in the mammalian kidney

(2010) Vidya K. Nagalakshmi et al.   KIDNEY INTERNATIONAL

Epigenetic modifications and human disease

(2010) Anna Portela et al.   NATURE BIOTECHNOLOGY

The NIH Roadmap Epigenomics Mapping Consortium

(2010) Bradley E Bernstein et al.   NATURE BIOTECHNOLOGY

Methylation determines fibroblast activation and fibrogenesis in the kidney

(2010) Wibke Bechtel et al.   NATURE MEDICINE

Charting histone modifications and the functional organization of mammalian genomes

(2010) Vicky W. Zhou et al.   NATURE REVIEWS GENETICS

Principles and challenges of genome-wide DNA methylation analysis

(2010) Peter W. Laird   NATURE REVIEWS GENETICS

New pharmacological treatments for improving renal outcomes in diabetes

(2010) Anne-Emilie Declèves et al.   Nature Reviews Nephrology

Metabolic memory and diabetic nephropathy: potential role for epigenetic mechanisms

(2010) Stephen Tonna et al.   Nature Reviews Nephrology

The RAAS in the pathogenesis and treatment of diabetic nephropathy

(2010) Piero Ruggenenti et al.   Nature Reviews Nephrology

Integrated Genetic and Epigenetic Analysis Identifies Haplotype-Specific Methylation in the FTO Type 2 Diabetes and Obesity Susceptibility Locus

(2010) Christopher G. Bell et al.   PLoS One

Epigenetics and maternal nutrition: nature v. nurture

(2010) Rebecca Simmons   PROCEEDINGS OF THE NUTRITION SOCIETY

MicroRNAs: Target Recognition and Regulatory Functions

(2009) David P. Bartel   CELL

Effects of Prior Intensive Insulin Therapy on Cardiac Autonomic Nervous System Function in Type 1 Diabetes Mellitus

(2009) Rodica Pop-Busui et al.   CIRCULATION

Podocytes produce homeostatic chemokine stromal cell-derived factor-1/CXCL12, which contributes to glomerulosclerosis, podocyte loss and albuminuria in a mouse model of type 2 diabetes

(2009) S. G. Sayyed et al.   DIABETOLOGIA

MicroRNA-21 protects from mesangial cell proliferation induced by diabetic nephropathy in db/db mice

(2009) Zheng Zhang et al.   FEBS LETTERS

Long noncoding RNAs: functional surprises from the RNA world

(2009) J. E. Wilusz et al.   GENES & DEVELOPMENT

Non-coding RNAs: regulators of disease

(2009) Ryan J Taft et al.   JOURNAL OF PATHOLOGY

Chromatin signature reveals over a thousand highly conserved large non-coding RNAs in mammals

(2009) Mitchell Guttman et al.   NATURE

TGF-β activates Akt kinase through a microRNA-dependent amplifying circuit targeting PTEN

(2009) Mitsuo Kato et al.   NATURE CELL BIOLOGY

Linking DNA methylation and histone modification: patterns and paradigms

(2009) Howard Cedar et al.   NATURE REVIEWS GENETICS

ChIP–seq: advantages and challenges of a maturing technology

(2009) Peter J. Park   NATURE REVIEWS GENETICS

Circulating microRNAs, potential biomarkers for drug-induced liver injury

(2009) K. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Enhanced Expression of Janus Kinase-Signal Transducer and Activator of Transcription Pathway Members in Human Diabetic Nephropathy

(2008) C. C. Berthier et al.   DIABETES

Lymphocytes From Patients With Type 1 Diabetes Display a Distinct Profile of Chromatin Histone H3 Lysine 9 Dimethylation: An Epigenetic Study in Diabetes

(2008) F. Miao et al.   DIABETES

From Fibrosis to Sclerosis: Mechanisms of Glomerulosclerosis in Diabetic Nephropathy

(2008) Y. Qian et al.   DIABETES

MicroRNA-377 is up-regulated and can lead to increased fibronectin production in diabetic nephropathy

(2008) Qiang Wang et al.   FASEB JOURNAL

MicroRNA-target pairs in the rat kidney identified by microRNA microarray, proteomic, and bioinformatic analysis

(2008) Z. Tian et al.   GENOME RESEARCH

Role of the Histone H3 Lysine 4 Methyltransferase, SET7/9, in the Regulation of NF-κB-dependent Inflammatory Genes

(2008) Yan Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Transient high glucose causes persistent epigenetic changes and altered gene expression during subsequent normoglycemia

(2008) Assam El-Osta et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Podocyte-Specific Deletion of Dicer Alters Cytoskeletal Dynamics and Causes Glomerular Disease

(2008) S. J. Harvey et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Podocyte-Specific Loss of Functional MicroRNAs Leads to Rapid Glomerular and Tubular Injury

(2008) J. Ho et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Podocyte-Selective Deletion of Dicer Induces Proteinuria and Glomerulosclerosis

(2008) S. Shi et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

The Identification of MicroRNAs in a Genomically Unstable Region of Human Chromosome 8q24

(2008) K. Huppi et al.   MOLECULAR CANCER RESEARCH

The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1

(2008) Philip A. Gregory et al.   NATURE CELL BIOLOGY

Mapping and quantifying mammalian transcriptomes by RNA-Seq

(2008) Ali Mortazavi et al.   NATURE METHODS

Mechanisms of post-transcriptional regulation by microRNAs: are the answers in sight?

(2008) Witold Filipowicz et al.   NATURE REVIEWS GENETICS

Intensive Blood Glucose Control and Vascular Outcomes in Patients with Type 2 Diabetes

(2008)   NEW ENGLAND JOURNAL OF MEDICINE

Effects of Intensive Glucose Lowering in Type 2 Diabetes

(2008)   NEW ENGLAND JOURNAL OF MEDICINE

Epigenetic histone H3 lysine 9 methylation in metabolic memory and inflammatory phenotype of vascular smooth muscle cells in diabetes

(2008) Louisa M. Villeneuve et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Targeted deletion of Dicer in the heart leads to dilated cardiomyopathy and heart failure

(2008) J.-F. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA