Enantioselective Aza-Henry Reaction of Imines Bearing a Benzothiazole Moiety Catalyzed by aCinchona-Based Squaramide

Asymmetric Synthesis of Dihydropyranones from Ynones by Sequential Copper(I)-Catalyzed Direct Aldol and Silver(I)-Catalyzed Oxy-Michael Reactions

(2012) Shi-Liang Shi et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis and anti-angiogenic activity of benzothiazole, benzimidazole containing phthalimide derivatives

(2012) Shunmugam Nagarajan et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Organocatalytic Enantioselective Michael-Addition of Malonic Acid Half-Thioesters to β-Nitroolefins: From Mimicry of Polyketide Synthases to Scalable Synthesis of γ-Amino Acids

(2011) Han Yong Bae et al.   ADVANCED SYNTHESIS & CATALYSIS

Chiral Squaramide-Catalyzed Highly Enantioselective Michael Addition of 2-Hydroxy-1,4-naphthoquinones to Nitroalkenes

(2011) Wen Yang et al.   ADVANCED SYNTHESIS & CATALYSIS

C3-Symmetrical Cinchonine-Squaramide as New Highly Efficient, and Recyclable Organocatalyst for Enantioselective Michael Addition

(2011) Chang Min et al.   ADVANCED SYNTHESIS & CATALYSIS

Bifunctional Cinchona Alkaloid Thiourea Catalyzed Highly Efficient, Enantioselective Aza-Henry Reaction of Cyclic Trifluoromethyl Ketimines: Synthesis of Anti-HIV Drug DPC 083

(2011) Hexin Xie et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis and biological evaluation of imidazolo[2,1-b]benzothiazole derivatives, as potential p53 inhibitors

(2011) Michael S. Christodoulou et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Chiral squaramide-catalyzed highly diastereo- and enantioselective direct Michael addition of nitroalkanes to nitroalkenes

(2011) Wen Yang et al.   CHEMICAL COMMUNICATIONS

Squaramides: physical properties, synthesis and applications

(2011) R. Ian Storer et al.   CHEMICAL SOCIETY REVIEWS

Squaramides: Bridging from Molecular Recognition to Bifunctional Organocatalysis

(2011) José Alemán et al.   CHEMISTRY-A EUROPEAN JOURNAL

Highly Enantioselective Synthesis of Orthogonally Protected (2S)-2,3-Diaminopropanoates through Catalytic Phase-Transfer Aza-Henry Reaction

(2011) Gullapalli Kumaraswamy et al.   HELVETICA CHIMICA ACTA

Squaramide-catalyzed enantioselective Michael addition of malononitrile to chalcones

(2011) Wen Yang et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Highly Enantioselective Synthesis of Polysubstituted TetrahydroquinolinesviaOrganocatalytic Michael/Aza-Henry Tandem Reactions

(2011) Zhen-Xin Jia et al.   ORGANIC LETTERS

Cu(I)-catalyzed decarboxylative aldol-type and Mannich-type reactions for asymmetric construction of contiguous trisubstituted and quaternary stereocenters

(2011) Liang Yin et al.   TETRAHEDRON

The use of samarium or sodium iodide salts as an alternative for the aza-Henry reaction

(2011) Humberto Rodríguez-Solla et al.   TETRAHEDRON

Asymmetric Mannich reactions catalyzed by cinchona alkaloid thiourea: enantioselective one-pot synthesis of novel β-amino ester derivatives

(2011) Song Bai et al.   TETRAHEDRON-ASYMMETRY

Highly enantioselective aza-Henry reaction promoted by amine-functionalized tridentate sulfinyl ligands

(2011) Michał Rachwalski et al.   TETRAHEDRON-ASYMMETRY

A Novel 18F-Labeled Imidazo[2,1-b]benzothiazole (IBT) for High-Contrast PET Imaging of β-Amyloid Plaques

(2011) Behrooz H. Yousefi et al.   ACS Medicinal Chemistry Letters

A Bifunctional Cinchona Alkaloid-Squaramide Catalyst for the Highly Enantioselective Conjugate Addition of Thiols to trans-Chalcones

(2010) Le Dai et al.   ADVANCED SYNTHESIS & CATALYSIS

Synthesis, DNA-binding ability and anticancer activity of benzothiazole/benzoxazole–pyrrolo[2,1-c][1,4]benzodiazepine conjugates

(2010) Ahmed Kamal et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Molecular docking and structure–activity relationship studies on benzothiazole based non-peptidic BACE-1 inhibitors

(2010) Weijun Xu et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Squaramide-catalyzed enantioselective Friedel–Crafts reaction of indoles with imines

(2010) Yong Qian et al.   CHEMICAL COMMUNICATIONS

Chiral Squaramides as Highly Enantioselective Catalysts for Michael Addition Reactions of 4-Hydroxycoumarins and 4-Hydroxypyrone to β,γ-Unsaturated α-Keto Esters

(2010) Dan-Qian Xu et al.   CHEMISTRY-A EUROPEAN JOURNAL

Highly Enantioselective 1,4-Michael Additions of Nucleophiles to Unsaturated Aryl Ketones with Organocatalysis by Bifunctional Cinchona Alkaloids

(2010) Cristina G. Oliva et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Acyl Phosphonates: Good Hydrogen Bond Acceptors and Ester/Amide Equivalents in Asymmetric Organocatalysis

(2010) Hao Jiang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Highly Enantioselective Michael Addition of Nitroalkanes to Chalcones Using Chiral Squaramides as Hydrogen Bonding Organocatalysts

(2010) Wen Yang et al.   ORGANIC LETTERS

Enantioselective α-Amination of 1,3-Dicarbonyl Compounds Using Squaramide Derivatives as Hydrogen Bonding Catalysts

(2010) Hideyuki Konishi et al.   ORGANIC LETTERS

One-Pot Enantioselective Syntheses of Iminosugar Derivatives Using Organocatalyticanti-Michael−anti-Aza-Henry Reactions

(2010) Ritsuo Imashiro et al.   ORGANIC LETTERS

Enantioselective Aza-Henry Reaction with Acyclic Guanidine-Thiourea Bifunctional Organocatalyst

(2009) Keisuke Takada et al.   ADVANCED SYNTHESIS & CATALYSIS

Naturally Occurring Nitrogen–Sulfur Compounds. The Benzothiazole Alkaloids

(2009) Lucille Le Bozec et al.   AUSTRALIAN JOURNAL OF CHEMISTRY

Catalytic Enantioselective Aza-Henry Reactions

(2009) Eugenia Marqués-López et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

A Novel Bis-Thiourea Organocatalyst for the Asymmetric Aza-Henry Reaction

(2008) Constantinos Rampalakos et al.   ADVANCED SYNTHESIS & CATALYSIS

Discovery of Bifunctional Thiourea/Secondary-Amine Organocatalysts for the Highly Stereoselective Nitro-Mannich Reaction of α-Substituted Nitroacetates

(2008) Bo Han et al.   CHEMISTRY-A EUROPEAN JOURNAL

Synthesis and Biological Properties of Benzothiazole, Benzoxazole, and Chromen-4-one Analogues of the Potent Antitumor Agent 2-(3,4-Dimethoxyphenyl)-5-fluorobenzothiazole (PMX 610, NSC 721648)(1)

(2008) Stefania Aiello et al.   JOURNAL OF MEDICINAL CHEMISTRY

A Diastereo- and Enantioselective Synthesis of α-Substitutedsyn-α,β-Diamino Acids

(2008) Anand Singh et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Highlyanti-Selective Asymmetric Nitro-Mannich Reactions Catalyzed by Bifunctional Amine-Thiourea-Bearing Multiple Hydrogen-Bonding Donors

(2008) Chun-Jiang Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Asymmetric Aza-Henry Reaction Under Phase Transfer Catalysis: An Experimental and Theoretical Study

(2008) Enrique Gomez-Bengoa et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Chiral Ammonium Betaines: A Bifunctional Organic Base Catalyst for Asymmetric Mannich-Type Reaction of α-Nitrocarboxylates

(2008) Daisuke Uraguchi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Chiral Squaramide Derivatives are Excellent Hydrogen Bond Donor Catalysts

(2008) Jeremiah P. Malerich et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Brønsted-Acid-Catalyzed Activation of Nitroalkanes: A Direct Enantioselective Aza-Henry Reaction

(2008) Magnus Rueping et al.   ORGANIC LETTERS

Novel Bifunctional Chiral Thiourea Catalyzed Highly Enantioselective aza-Henry Reaction†

(2008) Chungui Wang et al.   ORGANIC LETTERS