Modulation of Immune Function by Polyphenols: Possible Contribution of Epigenetic Factors

Epigenetic Regulation of Foxp3 Expression in Regulatory T Cells by DNA Methylation

(2014) G. Lal et al.   JOURNAL OF IMMUNOLOGY

Monocyte-macrophage membrane possesses free radicals scavenging activity: stimulation by polyphenols or by paraoxonase 1 (PON1)

(2013) M. Rosenblat et al.   FREE RADICAL RESEARCH

Expression profiles of miRNAs in polarized macrophages

(2013) YINGYING ZHANG et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

MicroRNA let-7c Regulates Macrophage Polarization

(2013) S. Banerjee et al.   JOURNAL OF IMMUNOLOGY

Dietary polyphenols in cancer prevention: the example of the flavonoid quercetin in leukemia

(2012) Carmela Spagnuolo et al.   Annals of the New York Academy of Sciences

Phytochemical Antioxidants Modulate Mammalian Cellular Epigenome: Implications in Health and Disease

(2012) Smitha Malireddy et al.   ANTIOXIDANTS & REDOX SIGNALING

Quince (Cydonia oblonga Miller) peel polyphenols modulate LPS-induced inflammation in human THP-1-derived macrophages through NF-κB, p38MAPK and Akt inhibition

(2012) Khadija Essafi-Benkhadir et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Baicalin, a natural compound, promotes regulatory T cell differentiation

(2012) Ji Yang et al.   BMC Complementary and Alternative Medicine

Anti-inflammatory activity of cinnamon water extract in vivo and in vitro LPS-induced models

(2012) Joung-Woo Hong et al.   BMC Complementary and Alternative Medicine

Molecular mechanisms of the cardiovascular protective effects of polyphenols

(2012) Ramaroson Andriantsitohaina et al.   BRITISH JOURNAL OF NUTRITION

Anti-Inflammatory Agents from Plants: Progress and Potential

(2012) M.C. Recio et al.   CURRENT MEDICINAL CHEMISTRY

Regulation of Proinflammatory Mediators via NF-κB and p38 MAPK-Dependent Mechanisms in RAW 264.7 Macrophages by Polyphenol Components Isolated from KoreaLonicera japonica THUNB

(2012) Kwang-Il Park et al.   Evidence-based Complementary and Alternative Medicine

Fisetin Inhibits Hyperglycemia-Induced Proinflammatory Cytokine Production by Epigenetic Mechanisms

(2012) Hye Joo Kim et al.   Evidence-based Complementary and Alternative Medicine

Identification of potent small-molecule inhibitors of STAT3 with anti-inflammatory properties in RAW 264.7 macrophages

(2012) Hemachander Capiralla et al.   FEBS Journal

The procyanidin trimer C1 inhibits LPS-induced MAPK and NF-κB signaling through TLR4 in macrophages

(2012) Eui-Baek Byun et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Dietary Flavonoid Naringenin Induces Regulatory T Cells via an Aryl Hydrocarbon Receptor Mediated Pathway

(2012) Hsi-Kai Wang et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Identifying Functional MicroRNAs in Macrophages with Polarized Phenotypes

(2012) Joel W. Graff et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Green tea epigallocatechin-3-gallate modulates differentiation of naïve CD4+ T cells into specific lineage effector cells

(2012) Junpeng Wang et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

A High-Throughput Chromatin Immunoprecipitation Approach Reveals Principles of Dynamic Gene Regulation in Mammals

(2012) Manuel Garber et al.   MOLECULAR CELL

Bilberries reduce low-grade inflammation in individuals with features of metabolic syndrome

(2012) Marjukka Kolehmainen et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Regulation of Inflammatory Cytokines in Lipopolysaccharide-Stimulated RAW 264.7 Murine Macrophage by 7-O-Methyl-naringenin

(2012) Lanan Wassy Soromou et al.   MOLECULES

An epigenetic silencing pathway controlling T helper 2 cell lineage commitment

(2012) Rhys S. Allan et al.   NATURE

Yerba mate (Ilex paraguariensis) enhances the gene modulation and activity of paraoxonase-2: In vitro and in vivo studies

(2012) Elenise Stucker Fernandes et al.   NUTRITION

Inhibition of Proinflammatory Biomarkers in THP1 Macrophages by Polyphenols Derived From Chamomile, Meadowsweet and Willow bark

(2012) Elaine M Drummond et al.   PHYTOTHERAPY RESEARCH

Modulation of miRNA Expression by Dietary Polyphenols in apoE Deficient Mice: A New Mechanism of the Action of Polyphenols

(2012) Dragan Milenkovic et al.   PLoS One

MicroRNA 10a Marks Regulatory T Cells

(2012) Lukas T. Jeker et al.   PLoS One

Akt1 and Akt2 protein kinases differentially contribute to macrophage polarization

(2012) A. Arranz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Epigenetic regulation of macrophage polarization and function

(2012) Lionel B. Ivashkiv   TRENDS IN IMMUNOLOGY

Re-polarization of tumor-associated macrophages to pro-inflammatory M1 macrophages by microRNA-155

(2012) Xing Cai et al.   Journal of Molecular Cell Biology

Antioxidant, Anti-inflammatory and Antiproliferative Activities of Kalanchoe gracilis (L.) DC Stem

(2011) Zhen-Rung Lai et al.   AMERICAN JOURNAL OF CHINESE MEDICINE

Differential effects of polyphenols and alcohol of red wine on the expression of adhesion molecules and inflammatory cytokines related to atherosclerosis: a randomized clinical trial

(2011) Gemma Chiva-Blanch et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Epigenetic modification of the human CCR6 gene is associated with stable CCR6 expression in T cells

(2011) S. Steinfelder et al.   BLOOD

(-)-Epigallocatechin-3-gallate reactivates silenced tumor suppressor genes, Cip1/p21 and p16INK4a, by reducing DNA methylation and increasing histones acetylation in human skin cancer cells

(2011) V. Nandakumar et al.   CARCINOGENESIS

Immunomodulatory activity of polyphenols derived from Cassia auriculata flowers in aged rats

(2011) Cini M. John et al.   CELLULAR IMMUNOLOGY

4-Hydroxynonenal Inhibits SIRT3 via Thiol-Specific Modification

(2011) Kristofer S. Fritz et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Effects of Flavonoids and other Polyphenols on Inflammation

(2011) R. González et al.   CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION

Histone Deacetylase Inhibition by Sodium Valproate Regulates Polarization of Macrophage Subsets

(2011) Chenming Wu et al.   DNA AND CELL BIOLOGY

Epigenotype switching at the CD14 and CD209 genes during differentiation of human monocytes to dendritic cells

(2011) Jörn Bullwinkel et al.   Epigenetics

Induction of regulatory T cells by green tea polyphenol EGCG

(2011) Carmen P. Wong et al.   IMMUNOLOGY LETTERS

Inhibition of the NF-κB signaling pathway by the curcumin analog, 3,5-Bis(2-pyridinylmethylidene)-4-piperidone (EF31): Anti-inflammatory and anti-cancer properties

(2011) Anlys Olivera et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

A Matured Fruit Extract of Date Palm Tree (Phoenix dactyliferaL.) Stimulates the Cellular Immune System in Mice

(2011) Koji Karasawa et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Blueberries reduce pro-inflammatory cytokine TNF-α and IL-6 production in mouse macrophages by inhibiting NF-κB activation and the MAPK pathway

(2011) Chenghui Xie et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Identification of Baicalin as an Immunoregulatory Compound by Controlling TH17 Cell Differentiation

(2011) Ji Yang et al.   PLoS One

Proanthocyanidins Modulate MicroRNA Expression in Human HepG2 Cells

(2011) Anna Arola-Arnal et al.   PLoS One

Polyphenols and Human Health: Prevention of Disease and Mechanisms of Action

(2011) David Vauzour et al.   Nutrients

Mechanisms Establishing TLR4-Responsive Activation States of Inflammatory Response Genes

(2011) Laure Escoubet-Lozach et al.   PLoS Genetics

Dietary phytochemicals, HDAC inhibition, and DNA damage/repair defects in cancer cells

(2011) Praveen Rajendran et al.   Clinical Epigenetics

Oxidative stress, inflammation, and cancer: How are they linked?

(2010) Simone Reuter et al.   FREE RADICAL BIOLOGY AND MEDICINE

Peripheral CD4+ T-cell differentiation regulated by networks of cytokines and transcription factors

(2010) Jinfang Zhu et al.   IMMUNOLOGICAL REVIEWS

Effect of quercetin and its metabolites isorhamnetin and quercetin-3-glucuronide on inflammatory gene expression: role of miR-155☆

(2010) Christine Boesch-Saadatmandi et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Epigenetic regulation of high glucose-induced proinflammatory cytokine production in monocytes by curcumin

(2010) Jung-Mi Yun et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Comprehensive methylome map of lineage commitment from haematopoietic progenitors

(2010) Hong Ji et al.   NATURE

Suppression of inflammation by a synthetic histone mimic

(2010) Edwige Nicodeme et al.   NATURE

Epigenetic modifications and human disease

(2010) Anna Portela et al.   NATURE BIOTECHNOLOGY

The Jmjd3-Irf4 axis regulates M2 macrophage polarization and host responses against helminth infection

(2010) Takashi Satoh et al.   NATURE IMMUNOLOGY

T Regulatory Cells in Cord Blood—FOXP3 Demethylation as Reliable Quantitative Marker

(2010) Jing Liu et al.   PLoS One

Chemistry and Biochemistry of Dietary Polyphenols

(2010) Rong Tsao   Nutrients

Epigenetic regulation of the alternatively activated macrophage phenotype

(2009) M. Ishii et al.   BLOOD

Control of Inducible Gene Expression by Signal-Dependent Transcriptional Elongation

(2009) Diana C. Hargreaves et al.   CELL

A Unifying Model for the Selective Regulation of Inducible Transcription by CpG Islands and Nucleosome Remodeling

(2009) Vladimir R. Ramirez-Carrozzi et al.   CELL

Natural Polyphenols as Direct Trapping Agents of Lipid Peroxidation-Derived Acrolein and 4-Hydroxy-trans-2-nonenal

(2009) Qin Zhu et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Resveratrol Alters Proliferative Responses and Apoptosis in Human Activated B Lymphocytes in Vitro

(2009) Susan J. Zunino et al.   JOURNAL OF NUTRITION

Curcumin is a potent DNA hypomethylation agent

(2008) Zhongfa Liu et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

B lymphocytes: how they develop and function

(2008) T. W. LeBien et al.   BLOOD

Regulatory T cells in inflammatory bowel disease

(2008) Elisa K Boden et al.   CURRENT OPINION IN GASTROENTEROLOGY

Retracted: Genistein mediated histone acetylation and demethylation activates tumor suppressor genes in prostate cancer cells

(2008) Nobuyuki Kikuno et al.   INTERNATIONAL JOURNAL OF CANCER

Regulatory T cells (Treg) in rheumatoid arthritis

(2008) Marie-Christophe Boissier et al.   JOINT BONE SPINE

Multiple Sclerosis and Regulatory T Cells

(2008) Cristina Maria Costantino et al.   JOURNAL OF CLINICAL IMMUNOLOGY

MicroRNAs and immunity: Novel players in the regulation of normal immune function and inflammation

(2008) Enikö Sonkoly et al.   SEMINARS IN CANCER BIOLOGY