Tyrosinase-Cre-Mediated Deletion of the Autophagy Gene Atg7 Leads to Accumulation of the RPE65 Variant M450 in the Retinal Pigment Epithelium of C57BL/6 Mice

Defects in retinal pigment epithelial cell proteolysis and the pathology associated with age-related macular degeneration

(2016) Deborah A. Ferrington et al.   PROGRESS IN RETINAL AND EYE RESEARCH

Identification of an Alternative Splicing Product of the Otx2 Gene Expressed in the Neural Retina and Retinal Pigmented Epithelial Cells

(2016) Christo Kole et al.   PLoS One

Deletion of autophagy inducerRB1CC1results in degeneration of the retinal pigment epithelium

(2015) Jingyu Yao et al.   Autophagy

p62/SQSTM1 functions as a signaling hub and an autophagy adaptor

(2015) Yoshinori Katsuragi et al.   FEBS Journal

Di-retinoid-pyridinium-ethanolamine (A2E) Accumulation and the Maintenance of the Visual Cycle Are Independent of Atg7-mediated Autophagy in the Retinal Pigmented Epithelium

(2015) Lindsay Perusek et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Suppression of Autophagy Dysregulates the Antioxidant Response and Causes Premature Senescence of Melanocytes

(2015) Cheng-Feng Zhang et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Improvement and Decline in Vision with Gene Therapy in Childhood Blindness

(2015) Samuel G. Jacobson et al.   NEW ENGLAND JOURNAL OF MEDICINE

Protective effect of autophagy on human retinal pigment epithelial cells against lipofuscin fluorophore A2E: implications for age-related macular degeneration

(2015) J Zhang et al.   Cell Death & Disease

Dysregulated autophagy in the RPE is associated with increased susceptibility to oxidative stress and AMD

(2014) Sayak K Mitter et al.   Autophagy

Lysosomal-mediated waste clearance in retinal pigment epithelial cells is regulated by CRYBA1/βA3/A1-crystallin via V-ATPase-MTORC1 signaling

(2014) Mallika Valapala et al.   Autophagy

p62 provides dual cytoprotection against oxidative stress in the retinal pigment epithelium

(2014) Lei Wang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Metabolic Control of Autophagy

(2014) Lorenzo Galluzzi et al.   CELL

Transcription Factor SOX9 Plays a Key Role in the Regulation of Visual Cycle Gene Expression in the Retinal Pigment Epithelium

(2014) Tomohiro Masuda et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Loss of Keratin K2 Expression Causes Aberrant Aggregation of K10, Hyperkeratosis, and Inflammation

(2014) Heinz Fischer et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

The Contribution of Melanoregulin to Microtubule-Associated Protein 1 Light Chain 3 (LC3) Associated Phagocytosis in Retinal Pigment Epithelium

(2014) Laura S. Frost et al.   MOLECULAR NEUROBIOLOGY

miR-410 Inhibition Induces RPE Differentiation of Amniotic Epithelial Stem Cells via Overexpression of OTX2 and RPE65

(2014) Soon Won Choi et al.   Stem Cell Reviews and Reports

Inhibition of autophagy induces retinal pigment epithelial cell damage by the lipofuscin fluorophore A2E

(2014) Khandakar A.S.M. Saadat et al.   FEBS Open Bio

Autophagy and heterophagy dysregulation leads to retinal pigment epithelium dysfunction and development of age-related macular degeneration

(2013) Kai Kaarniranta et al.   Autophagy

Noncanonical Autophagy Promotes the Visual Cycle

(2013) Ji-Young Kim et al.   CELL

Nrf2 signaling is impaired in the aging RPE given an oxidative insult

(2013) Mira M. Sachdeva et al.   EXPERIMENTAL EYE RESEARCH

Epidermal keratinocytes form a functional skin barrier in the absence of Atg7 dependent autophagy

(2013) Heidemarie Rossiter et al.   JOURNAL OF DERMATOLOGICAL SCIENCE

Autophagy in Human Health and Disease

(2013) Augustine M.K. Choi et al.   NEW ENGLAND JOURNAL OF MEDICINE

Conditional Ablation of the Choroideremia Gene Causes Age-Related Changes in Mouse Retinal Pigment Epithelium

(2013) Silène T. Wavre-Shapton et al.   PLoS One

Autophagy Activation Clears ELAVL1/HuR-Mediated Accumulation of SQSTM1/p62 during Proteasomal Inhibition in Human Retinal Pigment Epithelial Cells

(2013) Johanna Viiri et al.   PLoS One

Targeted deletion of Atg5 reveals differential roles of autophagy in keratin K5-expressing epithelia

(2012) Supawadee Sukseree et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Autophagy in the Thymic Epithelium Is Dispensable for the Development of Self-Tolerance in a Novel Mouse Model

(2012) Supawadee Sukseree et al.   PLoS One

New insights into retinoid metabolism and cycling within the retina

(2012) Peter H. Tang et al.   PROGRESS IN RETINAL AND EYE RESEARCH

Autophagy: Renovation of Cells and Tissues

(2011) Noboru Mizushima et al.   CELL

Age-Related Retinopathy in NRF2-Deficient Mice

(2011) Zhenyang Zhao et al.   PLoS One

Using LC3 to monitor autophagy flux in the retinal pigment epithelium

(2009) Ai Ling Wang et al.   Autophagy

Retinal Pigment Epithelium-Retinal G Protein Receptor-Opsin Mediates Light-dependent Translocation of All-trans-retinyl Esters for Synthesis of Visual Chromophore in Retinal Pigment Epithelial Cells

(2008) Roxana A. Radu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Histidase expression in human epidermal keratinocytes: Regulation by differentiation status and all-trans retinoic acid

(2008) Leopold Eckhart et al.   JOURNAL OF DERMATOLOGICAL SCIENCE