Autophagy Activation Clears ELAVL1/HuR-Mediated Accumulation of SQSTM1/p62 during Proteasomal Inhibition in Human Retinal Pigment Epithelial Cells

nELAV Proteins Alteration in Alzheimer's Disease Brain: A Novel Putative Target for Amyloid-β Reverberating on AβPP Processing

(2017) Marialaura Amadio et al.   JOURNAL OF ALZHEIMERS DISEASE

Does bafilomycin A1block the fusion of autophagosomes with lysosomes?

(2014) Daniel J. Klionsky et al.   Autophagy

A novel link between autophagy and the ubiquitin-proteasome system

(2014) Viktor I. Korolchuk et al.   Autophagy

Autophagy and heterophagy dysregulation leads to retinal pigment epithelium dysfunction and development of age-related macular degeneration

(2013) Kai Kaarniranta et al.   Autophagy

Lifestyle modification, nutritional and vitamins supplements for age-related macular degeneration

(2012) Helena P. Y. Sin et al.   ACTA OPHTHALMOLOGICA

Guidelines for the use and interpretation of assays for monitoring autophagy

(2012) Daniel J. Klionsky et al.   Autophagy

Sequestosome 1/p62: across diseases

(2012) Thangiah Geetha et al.   BIOMARKERS

AMP-activated protein kinase (AMPK) controls the aging process via an integrated signaling network

(2011) Antero Salminen et al.   AGEING RESEARCH REVIEWS

Autophagy: Renovation of Cells and Tissues

(2011) Noboru Mizushima et al.   CELL

The complex world of post-transcriptional mechanisms: is their deregulation a common link for diseases? Focus on ELAV-like RNA-binding proteins

(2011) Alessia Pascale et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

HuR function in disease

(2011) Subramanya Srikantan   Frontiers in Bioscience-Landmark

Ranibizumab and Bevacizumab for Neovascular Age-Related Macular Degeneration

(2011)   NEW ENGLAND JOURNAL OF MEDICINE

Emerging role of p62/sequestosome-1 in the pathogenesis of Alzheimer's disease

(2011) Antero Salminen et al.   PROGRESS IN NEUROBIOLOGY

p62/SQSTM1Is a Target Gene for Transcription Factor NRF2 and Creates a Positive Feedback Loop by Inducing Antioxidant Response Element-driven Gene Transcription

(2010) Ashish Jain et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nerve cells immunoreactive for p62 in select hypothalamic and brainstem nuclei of controls and Parkinson’s disease cases

(2010) Heiko Braak et al.   JOURNAL OF NEURAL TRANSMISSION

Eaten alive: a history of macroautophagy

(2010) Zhifen Yang et al.   NATURE CELL BIOLOGY

Heat shock proteins as gatekeepers of proteolytic pathways—Implications for age-related macular degeneration (AMD)

(2009) Kai Kaarniranta et al.   AGEING RESEARCH REVIEWS

Mitochondrial Turnover and Aging of Long-Lived Postmitotic Cells: The Mitochondrial–Lysosomal Axis Theory of Aging

(2009) Alexei Terman et al.   ANTIOXIDANTS & REDOX SIGNALING

ARPE-19 retinal pigment epitheliaL CELLS are highly resistant to oxidative stress and exercise strict control over their lysosomal redox-active iron

(2009) Tino Kurz et al.   Autophagy

Autophagy, exosomes and drusen formation in age-related macular degeneration

(2009) Ai Ling Wang et al.   Autophagy

Using LC3 to monitor autophagy flux in the retinal pigment epithelium

(2009) Ai Ling Wang et al.   Autophagy

Mammalian autophagy: core molecular machinery and signaling regulation

(2009) Zhifen Yang et al.   CURRENT OPINION IN CELL BIOLOGY

Lipid peroxidation products reduce lysosomal protease activities in human retinal pigment epithelial cells via two different mechanisms of action

(2009) Tim U. Krohne et al.   EXPERIMENTAL EYE RESEARCH

NF-κB signaling as a putative target for ω-3 metabolites in the prevention of age-related macular degeneration (AMD)

(2009) Kai Kaarniranta et al.   EXPERIMENTAL GERONTOLOGY

Nucleocytoplasmic Shuttling of p62/SQSTM1 and Its Role in Recruitment of Nuclear Polyubiquitinated Proteins to Promyelocytic Leukemia Bodies

(2009) Serhiy Pankiv et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Tristetraprolin Is Required for Full Anti-Inflammatory Response of Murine Macrophages to IL-10

(2009) B. Schaljo et al.   JOURNAL OF IMMUNOLOGY

Autophagy Inhibition Compromises Degradation of Ubiquitin-Proteasome Pathway Substrates

(2009) Viktor I. Korolchuk et al.   MOLECULAR CELL

Regulation of the aging process by autophagy

(2009) Antero Salminen et al.   TRENDS IN MOLECULAR MEDICINE

Role of AMP-activated protein kinase in autophagy and proteasome function

(2008) Rosa Viana et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Post-Transcriptional Regulation of HSP70 Expression Following Oxidative Stress in SH-SY5Y Cells: The Potential Involvement of the RNA-Binding Protein HuR

(2008) M. Amadio et al.   CURRENT PHARMACEUTICAL DESIGN

Alterations of activity and intracellular distribution of the 20S proteasome in ageing retinal pigment epithelial cells

(2008) Yue Li et al.   EXPERIMENTAL GERONTOLOGY

Crosstalk between Hsp70 molecular chaperone, lysosomes and proteasomes in autophagy-mediated proteolysis in human retinal pigment epithelial cells

(2008) Tuomas Ryhänen et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Age-Related Macular Degeneration

(2008) Rama D. Jager et al.   NEW ENGLAND JOURNAL OF MEDICINE

miR-519 reduces cell proliferation by lowering RNA-binding protein HuR levels

(2008) K. Abdelmohsen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA