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Autophagy and heterophagy dysregulation leads to retinal pigment epithelium dysfunction and development of age-related macular degeneration

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Characteristics of fundus autofluorescence and drusen in the fellow eyes of Japanese patients with exudative age-related macular degeneration

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Adrenomedullin Inhibits Choroidal Neovascularization via CCL2 in the Retinal Pigment Epithelium

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Mitochondrial DNA that escapes from autophagy causes inflammation and heart failure

(2012) Takafumi Oka et al.   NATURE

Mechanisms of Age-Related Macular Degeneration

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Autophagy: Renovation of Cells and Tissues

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The bisretinoids of retinal pigment epithelium

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Effects of lipid peroxidation products on lipofuscinogenesis and autophagy in human retinal pigment epithelial cells

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A role for mitochondria in NLRP3 inflammasome activation

(2010) Rongbin Zhou et al.   NATURE

Inhibition of the visual cycle by A2E through direct interaction with RPE65 and implications in Stargardt disease

(2010) Gennadiy Moiseyev et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Retinal ultrastructure of murine models of dry age-related macular degeneration (AMD)

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A2E, a Pigment of the Lipofuscin of Retinal Pigment Epithelial Cells, Is an Endogenous Ligand for Retinoic Acid Receptor

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Parkin is recruited selectively to impaired mitochondria and promotes their autophagy

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Autophagy fights disease through cellular self-digestion

(2008) Noboru Mizushima et al.   NATURE