Sequencing the functional antibody repertoire—diagnostic and therapeutic discovery
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Title
Sequencing the functional antibody repertoire—diagnostic and therapeutic discovery
Authors
Keywords
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Journal
Nature Reviews Rheumatology
Volume 11, Issue 3, Pages 171-182
Publisher
Springer Nature
Online
2014-12-23
DOI
10.1038/nrrheum.2014.220
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Note: Only part of the references are listed.- Human Responses to Influenza Vaccination Show Seroconversion Signatures and Convergent Antibody Rearrangements
- (2014) Katherine J.L. Jackson et al. Cell Host & Microbe
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- (2014) T. Cantaert et al. JOURNAL OF IMMUNOLOGY
- Clonal selection in the germinal centre by regulated proliferation and hypermutation
- (2014) Alexander D. Gitlin et al. NATURE
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- (2014) Barbara Treutlein et al. NATURE
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- (2014) Brian A Kidd et al. NATURE IMMUNOLOGY
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- (2014) Mikhail Shugay et al. NATURE METHODS
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- (2014) Uri Laserson et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Massively Parallel Single-Cell RNA-Seq for Marker-Free Decomposition of Tissues into Cell Types
- (2014) D. A. Jaitin et al. SCIENCE
- Street-Experienced Peripheral B Cells Traffic to the Brain
- (2014) D. R. Lu et al. Science Translational Medicine
- Immunoglobulin class-switched B cells form an active immune axis between CNS and periphery in multiple sclerosis
- (2014) A. Palanichamy et al. Science Translational Medicine
- B cells populating the multiple sclerosis brain mature in the draining cervical lymph nodes
- (2014) J. N. H. Stern et al. Science Translational Medicine
- Improved Survival with T Cell Clonotype Stability After Anti-CTLA-4 Treatment in Cancer Patients
- (2014) E. Cha et al. Science Translational Medicine
- Barcode-Enabled Sequencing of Plasmablast Antibody Repertoires in Rheumatoid Arthritis
- (2014) Yann-Chong Tan et al. Arthritis & Rheumatology
- Differences in the Composition of the Human Antibody Repertoire by B Cell Subsets in the Blood
- (2014) Eva Szymanska Mroczek et al. Frontiers in Immunology
- Reconstructing a B-Cell Clonal Lineage. II. Mutation, Selection, and Affinity Maturation
- (2014) Thomas B. Kepler et al. Frontiers in Immunology
- Complete Haplotype Sequence of the Human Immunoglobulin Heavy-Chain Variable, Diversity, and Joining Genes and Characterization of Allelic and Copy-Number Variation
- (2013) Corey T. Watson et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Circulating plasmablasts/plasmacells as a source of anticitrullinated protein antibodies in patients with rheumatoid arthritis
- (2013) Priscilla F Kerkman et al. ANNALS OF THE RHEUMATIC DISEASES
- Rheumatoid arthritis synovial tissue harbours dominant B-cell and plasma-cell clones associated with autoreactivity
- (2013) M E Doorenspleet et al. ANNALS OF THE RHEUMATIC DISEASES
- Temporal Response of the Human Virome to Immunosuppression and Antiviral Therapy
- (2013) Iwijn De Vlaminck et al. CELL
- Convergent Antibody Signatures in Human Dengue
- (2013) Poornima Parameswaran et al. Cell Host & Microbe
- Impact of new sequencing technologies on studies of the human B cell repertoire
- (2013) Jessica A Finn et al. CURRENT OPINION IN IMMUNOLOGY
- Immunosequencing: applications of immune repertoire deep sequencing
- (2013) Harlan Robins CURRENT OPINION IN IMMUNOLOGY
- When and where does inflammation begin in rheumatoid arthritis?
- (2013) M. Kristen Demoruelle et al. CURRENT OPINION IN RHEUMATOLOGY
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- (2013) Christian E. Busse et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Monoclonal IgG antibodies generated from joint-derived B cells of RA patients have a strong bias toward citrullinated autoantigen recognition
- (2013) Khaled Amara et al. JOURNAL OF EXPERIMENTAL MEDICINE
- High-throughput sequencing of the paired human immunoglobulin heavy and light chain repertoire
- (2013) Brandon J DeKosky et al. NATURE BIOTECHNOLOGY
- Quantitative single-cell RNA-seq with unique molecular identifiers
- (2013) Saiful Islam et al. NATURE METHODS
- Quantitative assessment of single-cell RNA-sequencing methods
- (2013) Angela R Wu et al. NATURE METHODS
- Mechanistic biomarkers for clinical decision making in rheumatic diseases
- (2013) William H. Robinson et al. Nature Reviews Rheumatology
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- (2013) James L. Riley NEW ENGLAND JOURNAL OF MEDICINE
- Genetic measurement of memory B-cell recall using antibody repertoire sequencing
- (2013) C. Vollmers et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Accelerating Next-Generation Vaccine Development for Global Disease Prevention
- (2013) W. C. Koff et al. SCIENCE
- Cancer Immunotherapy
- (2013) J. Couzin-Frankel SCIENCE
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- (2013) N. Jiang et al. Science Translational Medicine
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- (2013) Jiang Zhu Frontiers in Microbiology
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- (2013) Pascale Mathonet et al. Frontiers in Immunology
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- (2012) Gabriel D. Victora et al. Annual Review of Immunology
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- (2012) M. Faham et al. BLOOD
- A Blueprint for HIV Vaccine Discovery
- (2012) Dennis R. Burton et al. Cell Host & Microbe
- Models and methods for analysis of lymphocyte repertoire generation, development, selection and evolution
- (2012) Ramit Mehr et al. IMMUNOLOGY LETTERS
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- (2012) Eng M. Tan JOURNAL OF CLINICAL INVESTIGATION
- Rapid and Massive Virus-Specific Plasmablast Responses during Acute Dengue Virus Infection in Humans
- (2012) J. Wrammert et al. JOURNAL OF VIROLOGY
- HIV therapy by a combination of broadly neutralizing antibodies in humanized mice
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- (2011) Andrew R M Bradbury et al. NATURE BIOTECHNOLOGY
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- (2011) Falk Hiepe et al. Nature Reviews Rheumatology
- High-throughput VDJ sequencing for quantification of minimal residual disease in chronic lymphocytic leukemia and immune reconstitution assessment
- (2011) A. C. Logan et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Focused Evolution of HIV-1 Neutralizing Antibodies Revealed by Structures and Deep Sequencing
- (2011) X. Wu et al. SCIENCE
- Sequence and Structural Convergence of Broad and Potent HIV Antibodies That Mimic CD4 Binding
- (2011) J. F. Scheid et al. SCIENCE
- A Neutralizing Antibody Selected from Plasma Cells That Binds to Group 1 and Group 2 Influenza A Hemagglutinins
- (2011) D. Corti et al. SCIENCE
- A Plasmablast Biomarker for Nonresponse to Antibody Therapy to CD20 in Rheumatoid Arthritis
- (2011) K. Owczarczyk et al. Science Translational Medicine
- Targeting TLRs Expands the Antibody Repertoire in Response to a Malaria Vaccine
- (2011) S. R. Wiley et al. Science Translational Medicine
- Immune complexes containing citrullinated fibrinogen costimulate macrophages via Toll-like receptor 4 and Fcγ receptor
- (2010) Jeremy Sokolove et al. ARTHRITIS AND RHEUMATISM
- High-throughput immunoglobulin repertoire analysis distinguishes between human IgM memory and switched memory B-cell populations
- (2010) Y.-C. Wu et al. BLOOD
- Development and Migration of Plasma Cells in the Mouse Lymph Node
- (2010) David R. Fooksman et al. IMMUNITY
- Individual Variation in the Germline Ig Gene Repertoire Inferred from Variable Region Gene Rearrangements
- (2010) S. D. Boyd et al. JOURNAL OF IMMUNOLOGY
- Monoclonal antibodies isolated without screening by analyzing the variable-gene repertoire of plasma cells
- (2010) Sai T Reddy et al. NATURE BIOTECHNOLOGY
- Improved Survival with Ipilimumab in Patients with Metastatic Melanoma
- (2010) F. Stephen Hodi et al. NEW ENGLAND JOURNAL OF MEDICINE
- Malignant mesothelioma-associated antigens recognized by tumor-infiltrating B cells and the clinical significance of the antibody titers
- (2009) Yoshiki Shigematsu et al. CANCER SCIENCE
- Broad diversity of neutralizing antibodies isolated from memory B cells in HIV-infected individuals
- (2009) Johannes F. Scheid et al. NATURE
- Sequencing technologies — the next generation
- (2009) Michael L. Metzker NATURE REVIEWS GENETICS
- Measurement and Clinical Monitoring of Human Lymphocyte Clonality by Massively Parallel V-D-J Pyrosequencing
- (2009) S. D. Boyd et al. Science Translational Medicine
- Autoimmune Responses in the Rheumatoid Synovium
- (2009) Rene E. M Toes et al. PLOS MEDICINE
- Ectopic Lymphoid Structures Support Ongoing Production of Class-Switched Autoantibodies in Rheumatoid Synovium
- (2009) Frances Humby et al. PLOS MEDICINE
- Phase 2 trial of a DNA vaccine encoding myelin basic protein for multiple sclerosis
- (2008) Hideki Garren et al. ANNALS OF NEUROLOGY
- B-cell tolerance checkpoints in health and autoimmunity
- (2008) Eric Meffre et al. CURRENT OPINION IN IMMUNOLOGY
- Frequency and Phenotype of Human Immunodeficiency Virus Envelope-Specific B Cells from Patients with Broadly Cross-Neutralizing Antibodies
- (2008) N. A. Doria-Rose et al. JOURNAL OF VIROLOGY
- Rapid cloning of high-affinity human monoclonal antibodies against influenza virus
- (2008) Jens Wrammert et al. NATURE
- Next-generation DNA sequencing
- (2008) Jay Shendure et al. NATURE BIOTECHNOLOGY
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