Long-lived autoreactive plasma cells drive persistent autoimmune inflammation

Cutting Edge: The Dependence of Plasma Cells and Independence of Memory B Cells on BAFF and APRIL

(2014) M. J. Benson et al.   JOURNAL OF IMMUNOLOGY

Megakaryocytes constitute a functional component of a plasma cell niche in the bone marrow

(2010) O. Winter et al.   BLOOD

Memory B and memory plasma cells

(2010) Taketoshi Yoshida et al.   IMMUNOLOGICAL REVIEWS

Type I interferons: crucial participants in disease amplification in autoimmunity

(2010) John C. Hall et al.   Nature Reviews Rheumatology

Reducing De Novo Donor-Specific Antibody Levels during Acute Rejection Diminishes Renal Allograft Loss

(2009) M. J. Everly et al.   AMERICAN JOURNAL OF TRANSPLANTATION

HLA-DRhigh/CD27high plasmablasts indicate active disease in patients with systemic lupus erythematosus

(2009) A M Jacobi et al.   ANNALS OF THE RHEUMATIC DISEASES

A retrospective seven-year analysis of the use of B cell depletion therapy in systemic lupus erythematosus at university college london hospital: The first fifty patients

(2009) Tim Y.-T. Lu et al.   ARTHRITIS AND RHEUMATISM

Effect of long-term belimumab treatment on b cells in systemic lupus erythematosus: Extension of a phase II, double-blind, placebo-controlled, dose-ranging study

(2009) Annett M. Jacobi et al.   ARTHRITIS AND RHEUMATISM

CXCR4 inhibitor AMD3100 disrupts the interaction of multiple myeloma cells with the bone marrow microenvironment and enhances their sensitivity to therapy

(2009) A. K. Azab et al.   BLOOD

Toward an Effective Targeted Chemotherapy for Multiple Myeloma

(2009) A. G. Polson et al.   CLINICAL CANCER RESEARCH

The Monoclonal Antibody nBT062 Conjugated to Cytotoxic Maytansinoids Has Selective Cytotoxicity Against CD138-Positive Multiple Myeloma Cells In vitro and In vivo

(2009) H. Ikeda et al.   CLINICAL CANCER RESEARCH

Adult stem cell transplantation in autoimmune disease

(2009) Alan Tyndall et al.   CURRENT OPINION IN HEMATOLOGY

Activating systemic autoimmunity: B's, T's, and tolls

(2009) Mark J Shlomchik   CURRENT OPINION IN IMMUNOLOGY

Induction of long-lived allergen-specific plasma cells by mucosal allergen challenge

(2009) Elke O. Luger et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Baseline autoantibody profiles predict normalization of complement and anti-dsDNA autoantibody levels following Rituximab treatment in systemic lupus erythematosus

(2009) GW Tew et al.   LUPUS

CD93 is required for maintenance of antibody secretion and persistence of plasma cells in the bone marrow niche

(2009) S. Chevrier et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Abrogation of Anti-HLA Antibodies via Proteasome Inhibition

(2009) Hargovind L. Trivedi et al.   TRANSPLANTATION

Proteasome Inhibition Reduces Donor-Specific Antibody Levels

(2009) M.J. Everly et al.   TRANSPLANTATION PROCEEDINGS

Residual inflammation after rituximab treatment is associated with sustained synovial plasma cell infiltration and enhanced B cell repopulation

(2008) Y K O Teng et al.   ANNALS OF THE RHEUMATIC DISEASES

Regulation and Functions of Blimp-1 in T and B Lymphocytes

(2008) Gislâine Martins et al.   Annual Review of Immunology

Induction of macrophage secretion of tumor necrosis factor α through Fcγ receptor IIa engagement by rheumatoid arthritis–specific autoantibodies to citrullinated proteins complexed with fibrinogen

(2008) Cyril Clavel et al.   ARTHRITIS AND RHEUMATISM

SDF-1/CXCR4 and VLA-4 interaction regulates homing in Waldenstrom macroglobulinemia

(2008) H. T. Ngo et al.   BLOOD

Depletion of autoreactive immunologic memory followed by autologous hematopoietic stem cell transplantation in patients with refractory SLE induces long-term remission through de novo generation of a juvenile and tolerant immune system

(2008) T. Alexander et al.   BLOOD

APRIL is critical for plasmablast survival in the bone marrow and poorly expressed by early-life bone marrow stromal cells

(2008) E. Belnoue et al.   BLOOD

Plasma cell differentiation and survival

(2008) David Tarlinton et al.   CURRENT OPINION IN IMMUNOLOGY

Migration of antibody secreting cells towards CXCL12 depends on the isotype that forms the BCR

(2008) Gertrude Achatz-Straussberger et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Osteoclasts support the survival of human plasma cells in vitro

(2008) A. Geffroy-Luseau et al.   INTERNATIONAL IMMUNOLOGY

The proteasome inhibitor bortezomib depletes plasma cells and protects mice with lupus-like disease from nephritis

(2008) Kirsten Neubert et al.   NATURE MEDICINE

Reactivation of Human Herpesvirus-6 in Natalizumab Treated Multiple Sclerosis Patients

(2008) Karen Yao et al.   PLoS One

Maintenance of the plasma cell pool is independent of memory B cells

(2008) A. Ahuja et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Technology Insight: hematopoietic stem cell transplantation for systemic rheumatic disease

(2008) Nikolay P Nikolov et al.   Nature clinical practice. Rheumatology

Levels of autoantibodies, unlike antibodies to all extrinsic antigen groups, fall following B cell depletion with Rituximab

(2007) Alastair J. Ferraro et al.   EUROPEAN JOURNAL OF IMMUNOLOGY