Onset of Immune Senescence Defined by Unbiased Pyrosequencing of Human Immunoglobulin mRNA Repertoires

Age Affects Quantity but Not Quality of Antibody Responses after Vaccination with an Inactivated Flavivirus Vaccine against Tick-Borne Encephalitis

(2012) Karin Stiasny et al.   PLoS One

Human Peripheral Blood Antibodies with Long HCDR3s Are Established Primarily at Original Recombination Using a Limited Subset of Germline Genes

(2012) Bryan S. Briney et al.   PLoS One

Expressed antibody repertoires in human cord blood cells: 454 sequencing and IMGT/HighV-QUEST analysis of germline gene usage, junctional diversity, and somatic mutations

(2011) Ponraj Prabakaran et al.   IMMUNOGENETICS

Genomic screening by 454 pyrosequencing identifies a new human IGHV gene and sixteen other new IGHV allelic variants

(2011) Yan Wang et al.   IMMUNOGENETICS

Divergent human populations show extensive shared IGK rearrangements in peripheral blood B cells

(2011) Katherine Jean Louise Jackson et al.   IMMUNOGENETICS

Aging Affects Human B Cell Responses

(2011) Daniela Frasca et al.   JOURNAL OF CLINICAL IMMUNOLOGY

Limited efficacy of inactivated influenza vaccine in elderly individuals is associated with decreased production of vaccine-specific antibodies

(2011) Sanae Sasaki et al.   JOURNAL OF CLINICAL INVESTIGATION

A Molecular Mechanism for TNF- -Mediated Downregulation of B Cell Responses

(2011) D. Frasca et al.   JOURNAL OF IMMUNOLOGY

Sequencing antibody repertoires

(2011) Nicolas Fischer   mAbs

Naive antibody gene-segment frequencies are heritable and unaltered by chronic lymphocyte ablation

(2011) J. Glanville et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Determinism and stochasticity during maturation of the zebrafish antibody repertoire

(2011) N. Jiang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Age effects on B cells and humoral immunity in humans

(2010) Daniela Frasca et al.   AGEING RESEARCH REVIEWS

A streamlined protocol for emulsion polymerase chain reaction and subsequent purification

(2010) Tatjana Schütze et al.   ANALYTICAL BIOCHEMISTRY

High-throughput immunoglobulin repertoire analysis distinguishes between human IgM memory and switched memory B-cell populations

(2010) Y.-C. Wu et al.   BLOOD

Structure and function of immunoglobulins

(2010) Harry W. Schroeder et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Individual Variation in the Germline Ig Gene Repertoire Inferred from Variable Region Gene Rearrangements

(2010) S. D. Boyd et al.   JOURNAL OF IMMUNOLOGY

Menopause and aging: Changes in the immune system—A review

(2010) Cátia Morgado Gameiro et al.   MATURITAS

Uracil residues dependent on the deaminase AID in immunoglobulin gene variable and switch regions

(2010) Robert W Maul et al.   NATURE IMMUNOLOGY

V-gene amplification revisited – An optimised procedure for amplification of rearranged human antibody genes of different isotypes

(2010) Theam Soon Lim et al.   New Biotechnology

Decreased antibody titers and booster responses in tick-borne encephalitis vaccinees aged 50–90 years

(2010) Birgit Weinberger et al.   VACCINE

Precise determination of the diversity of a combinatorial antibody library gives insight into the human immunoglobulin repertoire

(2009) J. Glanville et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

High-Throughput Sequencing of the Zebrafish Antibody Repertoire

(2009) J. A. Weinstein et al.   SCIENCE

B-cell diversity decreases in old age and is correlated with poor health status

(2008) Kate L. Gibson et al.   AGING CELL

Mechanism and Regulation of Class Switch Recombination

(2008) Janet Stavnezer et al.   Annual Review of Immunology

Biology of Immune Responses to Vaccines in Elderly Persons

(2008) Birgit Weinberger et al.   CLINICAL INFECTIOUS DISEASES

IMGT/V-QUEST: the highly customized and integrated system for IG and TR standardized V-J and V-D-J sequence analysis

(2008) X. Brochet et al.   NUCLEIC ACIDS RESEARCH

IMGT(R), the international ImMunoGeneTics information system(R)

(2008) M.-P. Lefranc et al.   NUCLEIC ACIDS RESEARCH