Epigenetics: deciphering its role in diabetes and its chronic complications

Curcumin activates the p38MPAK-HSP25 pathway in vitro but fails to attenuate diabetic nephropathy in DBA2J mice despite urinary clearance documented by HPLC

(2016) Jun Ma et al.   BMC Complementary and Alternative Medicine

DNA methylation profiling identifies epigenetic differences between diabetes patients with ESRD and diabetes patients without nephropathy

(2011) Carmen Sapienza et al.   Epigenetics

Renal Failure Increases Cardiac Histone H3 Acetylation, Dimethylation, and Phosphorylation and the Induction of Cardiomyopathy-Related Genes in Type 2 Diabetes

(2010) Anil Bhanudas Gaikwad et al.   AMERICAN JOURNAL OF PATHOLOGY

Genome-wide DNA methylation analysis for diabetic nephropathy in type 1 diabetes mellitus

(2010) Christopher G Bell et al.   BMC Medical Genomics

Enhanced Levels of microRNA-125b in Vascular Smooth Muscle Cells of Diabetic db/db Mice Lead to Increased Inflammatory Gene Expression by Targeting the Histone Methyltransferase Suv39h1

(2010) L. M. Villeneuve et al.   DIABETES

DNA methylation profiling in cell models of diabetic nephropathy

(2010) Eoin P. Brennan et al.   Epigenetics

Epigenetic Histone Methylation Modulates Fibrotic Gene Expression

(2010) G. Sun et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Early recognition and prevention of chronic kidney disease

(2010) Matthew T James et al.   LANCET

Metabolic memory and diabetic nephropathy: potential role for epigenetic mechanisms

(2010) Stephen Tonna et al.   Nature Reviews Nephrology

Progressive glomerulosclerosis in type 2 diabetes is associated with renal histone H3K9 and H3K23 acetylation, H3K4 dimethylation and phosphorylation at serine 10

(2010) Sufyan G. Sayyed et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Transcriptional coactivator p300 regulates glucose-induced gene expression in endothelial cells

(2009) Shali Chen et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Epigenetics in cancer

(2009) S. Sharma et al.   CARCINOGENESIS

Effects of Prior Intensive Insulin Therapy on Cardiac Autonomic Nervous System Function in Type 1 Diabetes Mellitus

(2009) Rodica Pop-Busui et al.   CIRCULATION

MicroRNAs and Their Role in Progressive Kidney Diseases

(2009) M. Kato et al.   Clinical Journal of the American Society of Nephrology

Epigenetics: A Molecular Link Between Environmental Factors and Type 2 Diabetes

(2009) Charlotte Ling et al.   DIABETES

Hyperglycemia Induces a Dynamic Cooperativity of Histone Methylase and Demethylase Enzymes Associated With Gene-Activating Epigenetic Marks That Coexist on the Lysine Tail

(2009) D. Brasacchio et al.   DIABETES

An operational definition of epigenetics

(2009) S. L. Berger et al.   GENES & DEVELOPMENT

BRG1 Increases Transcription of Proinflammatory Genes in Renal Ischemia

(2009) M. Naito et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Role of Jhdm2a in regulating metabolic gene expression and obesity resistance

(2009) Keisuke Tateishi et al.   NATURE

Metabolic memory: implications for diabetic vascular complications

(2009) Mark E Cooper   PEDIATRIC DIABETES

Role of Src Tyrosine Kinase in the Atherogenic Effects of the 12/15-Lipoxygenase Pathway in Vascular Smooth Muscle Cells

(2008) Marpadga A. Reddy et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Emerging Biomarkers for Evaluating Cardiovascular Risk in the Chronic Kidney Disease Patient: How Do New Pieces Fit into the Uremic Puzzle?

(2008) P. Stenvinkel et al.   Clinical Journal of the American Society of Nephrology

Lymphocytes From Patients With Type 1 Diabetes Display a Distinct Profile of Chromatin Histone H3 Lysine 9 Dimethylation: An Epigenetic Study in Diabetes

(2008) F. Miao et al.   DIABETES

Oscillating Glucose Is More Deleterious to Endothelial Function and Oxidative Stress Than Mean Glucose in Normal and Type 2 Diabetic Patients

(2008) A. Ceriello et al.   DIABETES

From Fibrosis to Sclerosis: Mechanisms of Glomerulosclerosis in Diabetic Nephropathy

(2008) Y. Qian et al.   DIABETES

Epigenetic regulation of PPARGC1A in human type 2 diabetic islets and effect on insulin secretion

(2008) C. Ling et al.   DIABETOLOGIA

Potential therapeutic effects of curcumin, the anti-inflammatory agent, against neurodegenerative, cardiovascular, pulmonary, metabolic, autoimmune and neoplastic diseases

(2008) Bharat B. Aggarwal et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Role of the Histone H3 Lysine 4 Methyltransferase, SET7/9, in the Regulation of NF-κB-dependent Inflammatory Genes

(2008) Yan Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Resistance of retinal inflammatory mediators to suppress after reinstitution of good glycemic control: novel mechanism for metabolic memory

(2008) Pooi-See Chan et al.   JOURNAL OF DIABETES AND ITS COMPLICATIONS

Transient high glucose causes persistent epigenetic changes and altered gene expression during subsequent normoglycemia

(2008) Assam El-Osta et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Type I Diabetes Leads to Tissue-Specific DNA Hypomethylation in Male Rats

(2008) Kelly T. Williams et al.   JOURNAL OF NUTRITION

Epigenetics and the control of epithelial sodium channel expression in collecting duct

(2008) Dongyu Zhang et al.   KIDNEY INTERNATIONAL

Epigenetic interplay between histone modifications and DNA methylation in gene silencing

(2008) T VAISSIERE et al.   MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH

Moving AHEAD with an international human epigenome project

(2008) et al.   NATURE

Effect of a Multifactorial Intervention on Mortality in Type 2 Diabetes

(2008) Peter Gæde et al.   NEW ENGLAND JOURNAL OF MEDICINE

10-Year Follow-up of Intensive Glucose Control in Type 2 Diabetes

(2008) Rury R. Holman et al.   NEW ENGLAND JOURNAL OF MEDICINE

Epigenetic histone H3 lysine 9 methylation in metabolic memory and inflammatory phenotype of vascular smooth muscle cells in diabetes

(2008) Louisa M. Villeneuve et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA