Resveratrol Modulates and Reverses the Age-Related Effect on Adenosine-Mediated Signalling in SAMP8 Mice

Purine-related metabolites and their converting enzymes are altered in frontal, parietal and temporal cortex at early stages of Alzheimer's disease pathology

(2018) Patricia Alonso-Andrés et al.   BRAIN PATHOLOGY

Natural Polyphenols in the Treatment of Alzheimer’s Disease

(2018) Syed-Badrul Syarifah-Noratiqah et al.   CURRENT DRUG TARGETS

Effect of Resveratrol on Oxidative Stress and Mitochondrial Dysfunction in Immature Brain during Epileptogenesis

(2018) Jaroslava Folbergrová et al.   MOLECULAR NEUROBIOLOGY

Resveratrol activation of AMPK-dependent pathways is neuroprotective in human neural stem cells against amyloid-beta-induced inflammation and oxidative stress

(2018) Ming-Chang Chiang et al.   NEUROCHEMISTRY INTERNATIONAL

The involvement of purinergic signalling in obesity

(2018) Geoffrey Burnstock et al.   Purinergic Signalling

Effects of vitamin D and resveratrol on metabolic associated markers in liver and adipose tissue from SAMP8 mice

(2017) Yehua Rui et al.   EXPERIMENTAL GERONTOLOGY

Resveratrol regulates neuro-inflammation and induces adaptive immunity in Alzheimer’s disease

(2017) Charbel Moussa et al.   Journal of Neuroinflammation

Resveratrol and Brain Mitochondria: a Review

(2017) Fernanda Rafaela Jardim et al.   MOLECULAR NEUROBIOLOGY

Resveratrol-Induced Effects on Body Fat Differ Depending on Feeding Conditions

(2017) Iñaki Milton-Laskibar et al.   MOLECULES

Adenosine A1 and A2A Receptors in the Brain: Current Research and Their Role in Neurodegeneration

(2017) et al.   MOLECULES

Resveratrol suppresses neuroinflammation in the experimental paradigm of autism spectrum disorders

(2017) Ranjana Bhandari et al.   NEUROCHEMISTRY INTERNATIONAL

SAMP8 mice as a neuropathological model of accelerated brain aging and dementia: Toshio Takeda's legacy and future directions

(2017) Ichiro Akiguchi et al.   NEUROPATHOLOGY

Anticonvulsant activity of resveratrol-loaded liposomes in vivo

(2017) M.S. Ethemoglu et al.   NEUROSCIENCE

Resveratrol ameliorates spatial learning memory impairment induced by Aβ 1–42 in rats

(2017) Rui Wang et al.   NEUROSCIENCE

Metabolic Stress Induces Cognitive Disturbances and Inflammation in Aged Mice: Protective Role of Resveratrol

(2017) Veronica Palomera-Ávalos et al.   REJUVENATION RESEARCH

Membrane cholesterol access into a G-protein-coupled receptor

(2017) Ramon Guixà-González et al.   Nature Communications

Protective Effect of Resveratrol on the Brain in a Rat Model of Epilepsy

(2017) Zhen Li et al.   Neuroscience Bulletin

Resveratrol and Amyloid-Beta: Mechanistic Insights

(2017) Yongming Jia et al.   Nutrients

Age-Related Decrease in Male Extra-Striatal Adenosine A1 Receptors Measured Using11C-MPDX PET

(2017) Masahiro Mishina et al.   Frontiers in Pharmacology

Caffeine Reverses Cognitive Impairment and Decreases Brain Amyloid-β Levels in Aged Alzheimer's Disease Mice

(2017) Gary W. Arendash et al.   JOURNAL OF ALZHEIMERS DISEASE

On the Dependency of Cellular Protein Levels on mRNA Abundance

(2016) Yansheng Liu et al.   CELL

Behaviour and cognitive changes correlated with hippocampal neuroinflammaging and neuronal markers in female SAMP8, a model of accelerated senescence

(2016) Christian Griñan-Ferré et al.   EXPERIMENTAL GERONTOLOGY

Down-regulation of glutamatergic terminals (VGLUT1) driven by Aβ in Alzheimer's disease

(2016) Manuel Rodriguez-Perdigon et al.   HIPPOCAMPUS

Therapy with resveratrol attenuates obesity-associated allergic airway inflammation in mice

(2016) Diana Majolli André et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

How does adenosine control neuronal dysfunction and neurodegeneration?

(2016) Rodrigo A. Cunha   JOURNAL OF NEUROCHEMISTRY

Anti-obesity effects of resveratrol: comparison between animal models and humans

(2016) Alfredo Fernández-Quintela et al.   JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY

Polyphenols in dementia: From molecular basis to clinical trials

(2016) Silvia Molino et al.   LIFE SCIENCES

Resveratrol Protects SAMP8 Brain Under Metabolic Stress: Focus on Mitochondrial Function and Wnt Pathway

(2016) V. Palomera-Avalos et al.   MOLECULAR NEUROBIOLOGY

Curcumin and Resveratrol in the Management of Cognitive Disorders: What is the Clinical Evidence?

(2016) Gabriela Mazzanti et al.   MOLECULES

Role of dietary phenols in mitigating microglia-mediated neuroinflammation

(2016) Parakalan Rangarajan et al.   NEUROMOLECULAR MEDICINE

Adenosine as a Multi-Signalling Guardian Angel in Human Diseases: When, Where and How Does it Exert its Protective Effects?

(2016) Pier Andrea Borea et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Early synaptic deficits in the APP/PS1 mouse model of Alzheimer’s disease involve neuronal adenosine A2A receptors

(2016) Silvia Viana da Silva et al.   Nature Communications

Resveratrol abrogates lipopolysaccharide-induced depressive-like behavior, neuroinflammatory response, and CREB/BDNF signaling in mice

(2015) Li Ge et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

IL-10 plays a pivotal role in anti-inflammatory effects of resveratrol in activated microglia cells

(2015) Antonia Cianciulli et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Hyperthermia-induced seizures alter adenosine A1and A2Areceptors and 5′-nucleotidase activity in rat cerebral cortex

(2015) David Agustín León-Navarro et al.   JOURNAL OF NEUROCHEMISTRY

Adenosine A2AR blockade prevents neuroinflammation-induced death of retinal ganglion cells caused by elevated pressure

(2015) Maria H. Madeira et al.   Journal of Neuroinflammation

Optogenetic activation of intracellular adenosine A2A receptor signaling in the hippocampus is sufficient to trigger CREB phosphorylation and impair memory

(2015) P Li et al.   MOLECULAR PSYCHIATRY

Astrocytic adenosine receptor A2A and Gs-coupled signaling regulate memory

(2015) Anna G Orr et al.   NATURE NEUROSCIENCE

Adenosine signalling in diabetes mellitus—pathophysiology and therapeutic considerations

(2015) Luca Antonioli et al.   Nature Reviews Endocrinology

A randomized, double-blind, placebo-controlled trial of resveratrol for Alzheimer disease

(2015) R. Scott Turner et al.   NEUROLOGY

Purine metabolism gene deregulation in Parkinson's disease

(2015) Paula Garcia-Esparcia et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Role of adenosine receptors in resveratrol-induced intraocular pressure lowering in rats with steroid-induced ocular hypertension

(2014) Norhafiza Razali et al.   CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY

Resveratrol in epilepsy: preventive or treatment opportunities?

(2014) Merc� Pall�s   Frontiers in Bioscience-Landmark

Role of Microglia Adenosine A2AReceptors in Retinal and Brain Neurodegenerative Diseases

(2014) Ana R. Santiago et al.   MEDIATORS OF INFLAMMATION

Increased striatal adenosine A2A receptor levels is an early event in Parkinson’s disease-related pathology and it is potentially regulated by miR-34b

(2014) Izaskun Villar-Menéndez et al.   NEUROBIOLOGY OF DISEASE

[60]Fullerene derivative modulates adenosine and metabotropic glutamate receptors gene expression: a possible protective effect against hypoxia

(2014) Davide Giust et al.   JOURNAL OF NANOBIOTECHNOLOGY

Resveratrol 3-O-d-glucuronide and resveratrol 4′-O-d-glucuronide inhibit colon cancer cell growth: Evidence for a role of A3 adenosine receptors, cyclin D1 depletion, and G1 cell cycle arrest

(2013) Elena Polycarpou et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Increased 5-Methylcytosine and Decreased 5-Hydroxymethylcytosine Levels are Associated with Reduced Striatal A2AR Levels in Huntington’s Disease

(2013) Izaskun Villar-Menéndez et al.   NEUROMOLECULAR MEDICINE

Dietary resveratrol prevents Alzheimer’s markers and increases life span in SAMP8

(2012) David Porquet et al.   AGE

Resveratrol Ameliorates Aging-Related Metabolic Phenotypes by Inhibiting cAMP Phosphodiesterases

(2012) Sung-Jun Park et al.   CELL

Resveratrol mediates anti-atherogenic effects on cholesterol flux in human macrophages and endothelium via PPARγ and adenosine

(2012) Iryna Voloshyna et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Resveratrol Engages AMPK to Attenuate ERK and mTOR Signaling in Sensory Neurons and Inhibits Incision-Induced Acute and Chronic Pain

(2012) Dipti V Tillu et al.   Molecular Pain

Desensitization of adenosine A1 receptors in rat immature cortical neurons

(2011) María Ángeles Ruiz et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Adenosine A2A receptors control neuroinflammation and consequent hippocampal neuronal dysfunction

(2011) Nelson Rebola et al.   JOURNAL OF NEUROCHEMISTRY

Cognitive Performances Are Selectively Enhanced during Chronic Caloric Restriction or Resveratrol Supplementation in a Primate

(2011) Alexandre Dal-Pan et al.   PLoS One

Resveratrol regulates human adipocyte number and function in a Sirt1-dependent manner

(2010) Pamela Fischer-Posovszky et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Adenosine A1 receptors using 8-dicyclopropylmethyl-1-[11C]methyl-3-propylxanthine PET in Alzheimer’s disease

(2009) Nobuyoshi Fukumitsu et al.   ANNALS OF NUCLEAR MEDICINE

Age-related expression of adenosine receptors in brain from the senescence-accelerated mouse

(2009) C.A. Castillo et al.   EXPERIMENTAL GERONTOLOGY

Adenosine A2A Receptor Blockade Prevents Synaptotoxicity and Memory Dysfunction Caused by  -Amyloid Peptides via p38 Mitogen-Activated Protein Kinase Pathway

(2009) P. M. Canas et al.   JOURNAL OF NEUROSCIENCE

Effects of resveratrol on nucleotide degrading enzymes in streptozotocin-induced diabetic rats

(2009) Roberta Schmatz et al.   LIFE SCIENCES

Reduced expression and desensitization of adenosine A1 receptor/adenylyl cyclase pathway after chronic (−)N6-phenylisopropyladenosine intake during pregnancy

(2009) D.A. León et al.   NEUROSCIENCE

RESEARCH ARTICLE: Up-regulation of Adenosine Receptors in the Frontal Cortex in Alzheimer's Disease

(2008) José L. Albasanz et al.   BRAIN PATHOLOGY