Adenosine signalling in diabetes mellitus—pathophysiology and therapeutic considerations

Diagnosis and classification of autoimmune diabetes mellitus

(2014) Silvia Canivell et al.   AUTOIMMUNITY REVIEWS

Diminished Adenosine A1 Receptor Expression in Pancreatic  -Cells May Contribute to the Pathology of Type 1 Diabetes

(2014) L. Yip et al.   DIABETES

Caffeinated and Decaffeinated Coffee Consumption and Risk of Type 2 Diabetes: A Systematic Review and a Dose-Response Meta-analysis

(2014) M. Ding et al.   DIABETES CARE

Inflammation as a link between obesity, metabolic syndrome and type 2 diabetes

(2014) Nathalie Esser et al.   DIABETES RESEARCH AND CLINICAL PRACTICE

Changes in coffee intake and subsequent risk of type 2 diabetes: three large cohorts of US men and women

(2014) Shilpa N. Bhupathiraju et al.   DIABETOLOGIA

Adenosine activates brown adipose tissue and recruits beige adipocytes via A2A receptors

(2014) Thorsten Gnad et al.   NATURE

The Macrophage A2b Adenosine Receptor Regulates Tissue Insulin Sensitivity

(2014) Hillary Johnston-Cox et al.   PLoS One

Potential roles of adenosine deaminase-2 in diabetic retinopathy

(2013) Nehal M. Elsherbiny et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The Role of Lifestyle Interventions in the Prevention of Gestational Diabetes

(2013) Ilana J. Halperin et al.   Current Diabetes Reports

The  -Cell/EC Axis: How Do Islet Cells Talk to Each Other?

(2013) H. Peiris et al.   DIABETES

The Protective Effects of CD39 Overexpression in Multiple Low-Dose Streptozotocin-Induced Diabetes in Mice

(2013) J. S. J. Chia et al.   DIABETES

A2B Adenosine Receptors Prevent Insulin Resistance by Inhibiting Adipose Tissue Inflammation via Maintaining Alternative Macrophage Activation

(2013) B. Csoka et al.   DIABETES

Diagnosis and Classification of Diabetes Mellitus

(2013)   DIABETES CARE

The elevated gene expression level of the A2Badenosine receptor is associated with hyperglycemia in women with gestational diabetes mellitus

(2013) Marzena Wojcik et al.   DIABETES-METABOLISM RESEARCH AND REVIEWS

Coffee and caffeine intake and incidence of type 2 diabetes mellitus: a meta-analysis of prospective studies

(2013) Xiubo Jiang et al.   EUROPEAN JOURNAL OF NUTRITION

Role of adenosine signalling and metabolism in β-cell regeneration

(2013) Olov Andersson   EXPERIMENTAL CELL RESEARCH

Possible involvement of A2A and A3 receptors in modulation of insulin secretion and β-cell survival in mouse pancreatic islets

(2013) M. Ohtani et al.   GENERAL AND COMPARATIVE ENDOCRINOLOGY

Blockade of A2B adenosine receptor reduces left ventricular dysfunction and ventricular arrhythmias 1 week after myocardial infarction in the rat model

(2013) Hao Zhang et al.   HEART RHYTHM

Dysfunctional CD39POSregulatory T cells and aberrant control of T-helper type 17 cells in autoimmune hepatitis

(2013) Charlotte R. Grant et al.   HEPATOLOGY

G Protein-Coupled Receptors and Adipogenesis: A Focus on Adenosine Receptors

(2013) Anna Eisenstein et al.   JOURNAL OF CELLULAR PHYSIOLOGY

TLR9 Deficiency Promotes CD73 Expression in T Cells and Diabetes Protection in Nonobese Diabetic Mice

(2013) N. Tai et al.   JOURNAL OF IMMUNOLOGY

Ticagrelor Increases Adenosine Plasma Concentration in Patients With an Acute Coronary Syndrome

(2013) Laurent Bonello et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

CD73-Dependent Generation of Adenosine and Endothelial Adora2b Signaling Attenuate Diabetic Nephropathy

(2013) E. Tak et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

The many faces of diabetes: a disease with increasing heterogeneity

(2013) Tiinamaija Tuomi et al.   LANCET

ABT-702, an adenosine kinase inhibitor, attenuates inflammation in diabetic retinopathy

(2013) Nehal M. Elsherbiny et al.   LIFE SCIENCES

The role of purinergic pathways in the pathophysiology of gut diseases: Pharmacological modulation and potential therapeutic applications

(2013) Luca Antonioli et al.   PHARMACOLOGY & THERAPEUTICS

Role of equilibrative adenosine transporters and adenosine receptors as modulators of the human placental endothelium in gestational diabetes mellitus

(2013) F. Pardo et al.   PLACENTA

Effect of Diabetes/Hyperglycemia on the Rat Retinal Adenosinergic System

(2013) Joana Vindeirinho et al.   PLoS One

Transcriptional Control of Hepatic Lipid Metabolism by SREBP and ChREBP

(2013) Xu Xu et al.   SEMINARS IN LIVER DISEASE

Ticagrelor versus prasugrel in diabetic patients with an acute coronary syndrome

(2013) Marc Laine et al.   THROMBOSIS AND HAEMOSTASIS

Immune mechanisms in type 1 diabetes

(2013) Maja Wållberg et al.   TRENDS IN IMMUNOLOGY

CD39 and CD73 in immunity and inflammation

(2013) Luca Antonioli et al.   TRENDS IN MOLECULAR MEDICINE

Diabetes: a 21st century challenge

(2013) Paul Z Zimmet et al.   Lancet Diabetes & Endocrinology

Dendritic Cell Subsets in Type 1 Diabetes: Friend or Foe?

(2013) Penelope A. Morel   Frontiers in Immunology

Improved blood glucose disposal and altered insulin secretion patterns in adenosine A1 receptor knockout mice

(2012) Gary K. Yang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Regulation of Lymphocyte Function by Adenosine

(2012) Joel Linden et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Adenosine Signaling Promotes Regeneration of Pancreatic β Cells In Vivo

(2012) Olov Andersson et al.   Cell Metabolism

Adenosine Deaminase in the Modulation of Immune System and its Potential as a Novel Target for Treatment of Inflammatory Disorders

(2012) Luca Antonioli et al.   CURRENT DRUG TARGETS

Effect of Caffeine and Capsaicin on the Blood Glucose Levels of Obese/Diabetic KK-Ay Mice

(2012) Tomoyuki Okumura et al.   Journal of Oleo Science

Adenosine A2B receptor-mediated VEGF induction promotes diabetic glomerulopathy

(2012) Angel Cárdenas et al.   LABORATORY INVESTIGATION

A cross-over study of the acute effects of espresso coffee on glucose tolerance and insulin sensitivity in people with type 2 diabetes mellitus

(2012) Jeremy D. Krebs et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Diabetic Retinopathy

(2012) David A. Antonetti et al.   NEW ENGLAND JOURNAL OF MEDICINE

Role of coffee in modulation of diabetes risk

(2012) Fausta Natella et al.   NUTRITION REVIEWS

The A2b Adenosine Receptor Modulates Glucose Homeostasis and Obesity

(2012) Hillary Johnston-Cox et al.   PLoS One

Adenosine kinase inhibition selectively promotes rodent and porcine islet  -cell replication

(2012) J. P. Annes et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Adenosine as an endogenous immunoregulator in cancer pathogenesis: where to go?

(2012) V. Kumar   Purinergic Signalling

A2A Adenosine Receptor (A2AAR) as a Therapeutic Target in Diabetic Retinopathy

(2011) Ahmed S. Ibrahim et al.   AMERICAN JOURNAL OF PATHOLOGY

The Endocannabinoid System and Plant-Derived Cannabinoids in Diabetes and Diabetic Complications

(2011) Béla Horváth et al.   AMERICAN JOURNAL OF PATHOLOGY

A 2b Adenosine Receptor Regulates Hyperlipidemia and Atherosclerosis

(2011) Milka Koupenova et al.   CIRCULATION

Impaired Glucose Tolerance in the Absence of Adenosine A1 Receptor Signaling

(2011) R. Faulhaber-Walter et al.   DIABETES

Links Between Insulin Resistance, Adenosine A2B Receptors, and Inflammatory Markers in Mice and Humans

(2011) R. A. Figler et al.   DIABETES

Beyond the Hormone: Insulin as an Autoimmune Target in Type 1 Diabetes

(2011) Vedran Brezar et al.   ENDOCRINE REVIEWS

Adenosine promotes alternative macrophage activation via A2A and A2B receptors

(2011) Balázs Csóka et al.   FASEB JOURNAL

Diabetic cardiomyopathy: understanding the molecular and cellular basis to progress in diagnosis and treatment

(2011) Inês Falcão-Pires et al.   HEART FAILURE REVIEWS

Contrasting effects of A1 and A2b adenosine receptors on adipogenesis

(2011) B Gharibi et al.   INTERNATIONAL JOURNAL OF OBESITY

High Levels of Adenosine Deaminase on Dendritic Cells Promote Autoreactive T Cell Activation and Diabetes in Nonobese Diabetic Mice

(2011) F. Ghaemi Oskouie et al.   JOURNAL OF IMMUNOLOGY

Purinergic signalling at the plasma membrane: a multipurpose and multidirectional mode to deal with amyotrophic lateral sclerosis and multiple sclerosis

(2011) Susanna Amadio et al.   JOURNAL OF NEUROCHEMISTRY

A2B receptors mediate the induction of early genes and inhibition of arterial smooth muscle cell proliferation via Epac

(2010) Peter Mayer et al.   CARDIOVASCULAR RESEARCH

Coffee and Caffeine Ameliorate Hyperglycemia, Fatty Liver, and Inflammatory Adipocytokine Expression in Spontaneously Diabetic KK-AyMice

(2010) Rie Yamauchi et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Genomics, Type 2 Diabetes, and Obesity

(2010) Mark I. McCarthy   NEW ENGLAND JOURNAL OF MEDICINE

Variants of the Adenosine A2A Receptor Gene Are Protective against Proliferative Diabetic Retinopathy in Patients with Type 1 Diabetes

(2010) Bashira A. Charles et al.   OPHTHALMIC RESEARCH

Macrophages and Diabetic Nephropathy

(2010) Greg H. Tesch   SEMINARS IN NEPHROLOGY

Nitric oxide reduces SLC29A1 promoter activity and adenosine transport involving transcription factor complex hCHOP–C/EBPα in human umbilical vein endothelial cells from gestational diabetes

(2009) Marcelo Farías et al.   CARDIOVASCULAR RESEARCH

Equilibrative Nucleoside Transporters in Fetal Endothelial Dysfunction in Diabetes Mellitus and Hyperglycaemia

(2009) Francisco Westermeier et al.   Current Vascular Pharmacology

Global estimates of the prevalence of diabetes for 2010 and 2030

(2009) J.E. Shaw et al.   DIABETES RESEARCH AND CLINICAL PRACTICE

Adenosine mediates transforming growth factor-beta 1 release in kidney glomeruli of diabetic rats

(2009) H. Roa et al.   FEBS LETTERS

Adenosine regulates CD8 T-cell priming by inhibition of membrane-proximal T-cell receptor signalling

(2009) Carsten Linnemann et al.   IMMUNOLOGY

Mechanisms of biphasic insulin-granule exocytosis - roles of the cytoskeleton, small GTPases and SNARE proteins

(2009) Z. Wang et al.   JOURNAL OF CELL SCIENCE

The A2B Adenosine Receptor Impairs the Maturation and Immunogenicity of Dendritic Cells

(2009) J. M. Wilson et al.   JOURNAL OF IMMUNOLOGY

Adenosine receptors in regulation of dendritic cell differentiation and function

(2008) S. V. Novitskiy et al.   BLOOD

Modulation of insulin release by adenosine A1receptor agonists and antagonists in INS-1 cells: The possible contribution of86Rb+efflux and45Ca2+uptake

(2008) M. Töpfer et al.   CELL BIOCHEMISTRY AND FUNCTION

Regulation of hepatic glucose production and the role of gluconeogenesis in humans: is the rate of gluconeogenesis constant?

(2008) Frank Q. Nuttall et al.   DIABETES-METABOLISM RESEARCH AND REVIEWS

Adenosine A2A receptor activation inhibits T helper 1 and T helper 2 cell development and effector function

(2008) Balázs Csóka et al.   FASEB JOURNAL

AMPK: a key regulator of energy balance in the single cell and the whole organism

(2008) D G Hardie   INTERNATIONAL JOURNAL OF OBESITY

Lack of A1 Adenosine Receptors Augments Diabetic Hyperfiltration and Glomerular Injury

(2008) R. Faulhaber-Walter et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Adenosine receptors: therapeutic aspects for inflammatory and immune diseases

(2008) György Haskó et al.   NATURE REVIEWS DRUG DISCOVERY

Adipocyte dysfunctions linking obesity to insulin resistance and type 2 diabetes

(2008) Adilson Guilherme et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Regulation of enteric functions by adenosine: Pathophysiological and pharmacological implications

(2008) Luca Antonioli et al.   PHARMACOLOGY & THERAPEUTICS

Skeletal Muscle Insulin Resistance: Roles of Fatty Acid Metabolism and Exercise

(2008) Lorraine P Turcotte et al.   PHYSICAL THERAPY