Angptl4 links α-cell proliferation following glucagon receptor inhibition with adipose tissue triglyceride metabolism
Published 2015 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Angptl4 links α-cell proliferation following glucagon receptor inhibition with adipose tissue triglyceride metabolism
Authors
Keywords
-
Journal
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Volume 112, Issue 50, Pages 15498-15503
Publisher
Proceedings of the National Academy of Sciences
Online
2015-12-01
DOI
10.1073/pnas.1513872112
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- A New Biology of Diabetes Revealed by Leptin
- (2015) Roger H. Unger et al. Cell Metabolism
- The FOXP1, FOXP2 and FOXP4 transcription factors are required for islet alpha cell proliferation and function in mice
- (2015) Jason M. Spaeth et al. DIABETOLOGIA
- Angiopoietin-like protein 8 (ANGPTL8)/betatrophin overexpression does not increase beta cell proliferation in mice
- (2015) Aaron R. Cox et al. DIABETOLOGIA
- In vivo targeted delivery of ANGPTL8 gene for beta cell regeneration in rats
- (2015) Jiaxi Chen et al. DIABETOLOGIA
- Insulin demand regulates β cell number via the unfolded protein response
- (2015) Rohit B. Sharma et al. JOURNAL OF CLINICAL INVESTIGATION
- Lack of glucagon receptor signaling and its implications beyond glucose homeostasis
- (2015) M. J. Charron et al. JOURNAL OF ENDOCRINOLOGY
- Glucagon Couples Hepatic Amino Acid Catabolism to mTOR-Dependent Regulation of α-Cell Mass
- (2015) Mark J. Solloway et al. Cell Reports
- ANGPTL4 mediates shuttling of lipid fuel to brown adipose tissue during sustained cold exposure
- (2015) Wieneke Dijk et al. eLife
- Perspectives on the Activities of ANGPTL8/Betatrophin
- (2014) Peng Yi et al. CELL
- ANGPTL8/Betatrophin Does Not Control Pancreatic Beta Cell Expansion
- (2014) Viktoria Gusarova et al. CELL
- Glucagon and Type 2 Diabetes: the Return of the Alpha Cell
- (2014) Asger Lund et al. Current Diabetes Reports
- IL-6-dependent proliferation of alpha cells in mice with partial pancreatic-duct ligation
- (2014) Ying Cai et al. DIABETOLOGIA
- Ablation of glucagon receptor signaling by peptide-based glucagon antagonists improves glucose tolerance in high fat fed mice
- (2014) Laura M. McShane et al. PEPTIDES
- Fatty acid-inducible ANGPTL4 governs lipid metabolic response to exercise
- (2014) M. Catoire et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- COMPARTMENTS: unification and visualization of protein subcellular localization evidence
- (2014) J. X. Binder et al. Database-The Journal of Biological Databases and Curation
- Reversal of β cell de-differentiation by a small molecule inhibitor of the TGFβ pathway
- (2014) Barak Blum et al. eLife
- RETRACTED: Betatrophin: A Hormone that Controls Pancreatic β Cell Proliferation
- (2013) Peng Yi et al. CELL
- Mice lacking ANGPTL8 (Betatrophin) manifest disrupted triglyceride metabolism without impaired glucose homeostasis
- (2013) Y. Wang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Identification of RIFL, a novel adipocyte-enriched insulin target gene with a role in lipid metabolism
- (2012) Gang Ren et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Lipasin, a novel nutritionally-regulated liver-enriched factor that regulates serum triglyceride levels
- (2012) Ren Zhang BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Free Fatty Acids Block Glucose-Induced -Cell Proliferation in Mice by Inducing Cell Cycle Inhibitors p16 and p18
- (2012) J. Pascoe et al. DIABETES
- Liver-Specific Disruption of the Murine Glucagon Receptor Produces -Cell Hyperplasia: Evidence for a Circulating -Cell Growth Factor
- (2012) C. Longuet et al. DIABETES
- Glucose metabolism: key endogenous regulator of β-cell replication and survival
- (2012) D. Dadon et al. DIABETES OBESITY & METABOLISM
- Regulation of Mouse Intestinal L Cell Progenitors Proliferation by the Glucagon Family of Peptides
- (2012) Marine Grigoryan et al. ENDOCRINOLOGY
- Pancreatic Beta Cells in Very Old Mice Retain Capacity for Compensatory Proliferation
- (2012) Miri Stolovich-Rain et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Angiopoietin-like 4 (Angptl4) Protein Is a Physiological Mediator of Intracellular Lipolysis in Murine Adipocytes
- (2012) Nora E. Gray et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Glucagonocentric restructuring of diabetes: a pathophysiologic and therapeutic makeover
- (2012) Roger H. Unger et al. JOURNAL OF CLINICAL INVESTIGATION
- Anti-Diabetic Efficacy and Impact on Amino Acid Metabolism of GRA1, a Novel Small-Molecule Glucagon Receptor Antagonist
- (2012) James Mu et al. PLoS One
- Metabolic manifestations of insulin deficiency do not occur without glucagon action
- (2012) Y. Lee et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Regulation of triglyceride metabolism by Angiopoietin-like proteins
- (2011) Frits Mattijssen et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- Angiopoietin-like 4: a decade of research
- (2011) Pengcheng Zhu et al. BIOSCIENCE REPORTS
- Polyomic profiling reveals significant hepatic metabolic alterations in glucagon-receptor (GCGR) knockout mice: implications on anti-glucagon therapies for diabetes
- (2011) Jianxin Yang et al. BMC GENOMICS
- Glucagon Receptor Knockout Prevents Insulin-Deficient Type 1 Diabetes in Mice
- (2011) Y. Lee et al. DIABETES
- Normal Glucagon Signaling and β-Cell Function After Near-Total α-Cell Ablation in Adult Mice
- (2011) Fabrizio Thorel et al. DIABETES
- The role of dysregulated glucagon secretion in type 2 diabetes
- (2011) D. D'Alessio DIABETES OBESITY & METABOLISM
- Insulin and Glucagon Regulate Pancreatic α-Cell Proliferation
- (2011) Zhuo Liu et al. PLoS One
- Angptl4 Protects against Severe Proinflammatory Effects of Saturated Fat by Inhibiting Fatty Acid Uptake into Mesenteric Lymph Node Macrophages
- (2010) Laeticia Lichtenstein et al. Cell Metabolism
- Caloric Restriction and Exercise Increase Plasma ANGPTL4 Levels in Humans via Elevated Free Fatty Acids
- (2009) Sander Kersten et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Insulin Signaling in α Cells Modulates Glucagon Secretion In Vivo
- (2009) Dan Kawamori et al. Cell Metabolism
- A Highly Conserved Motif within the NH2-terminal Coiled-coil Domain of Angiopoietin-like Protein 4 Confers Its Inhibitory Effects on Lipoprotein Lipase by Disrupting the Enzyme Dimerization
- (2009) Ming-hon Yau et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Angiopoietin-like 4 (ANGPTL4, Fasting-induced Adipose Factor) Is a Direct Glucocorticoid Receptor Target and Participates in Glucocorticoid-regulated Triglyceride Metabolism
- (2009) Suneil K. Koliwad et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Adipose tissue as an endocrine organ
- (2009) Sandra Galic et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- Homozygous P86S Mutation of the Human Glucagon Receptor Is Associated With Hyperglucagonemia, α Cell Hyperplasia, and Islet Cell Tumor
- (2009) Cuiqi Zhou et al. PANCREAS
- The Glucagon Receptor Is Required for the Adaptive Metabolic Response to Fasting
- (2008) Christine Longuet et al. Cell Metabolism
- Beneficial effects of lipids and prolactin on insulin secretion and β-cell proliferation: a role for lipids in the adaptation of islets to pregnancy
- (2008) T Clark Brelje et al. JOURNAL OF ENDOCRINOLOGY
- Interleukin-6 regulates pancreatic -cell mass expansion
- (2008) H. Ellingsgaard et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started