The FOXP1, FOXP2 and FOXP4 transcription factors are required for islet alpha cell proliferation and function in mice

Foxa1 and Foxa2 Regulate α-Cell Differentiation, Glucagon Biosynthesis, and Secretion

(2014) Mounia Heddad Masson et al.   ENDOCRINOLOGY

Inactivation of specific β cell transcription factors in type 2 diabetes

(2013) Shuangli Guo et al.   JOURNAL OF CLINICAL INVESTIGATION

Epigenomic plasticity enables human pancreatic α to β cell reprogramming

(2013) Nuria C. Bramswig et al.   JOURNAL OF CLINICAL INVESTIGATION

Reprogramming of Various Cell Types to a Beta-Like State by Pdx1, Ngn3 and MafA

(2013) Ersin Akinci et al.   PLoS One

Nkx6.1 Controls a Gene Regulatory Network Required for Establishing and Maintaining Pancreatic Beta Cell Identity

(2013) Ashleigh E. Schaffer et al.   PLoS Genetics

The Inactivation of Arx in Pancreatic α-Cells Triggers Their Neogenesis and Conversion into Functional β-Like Cells

(2013) Monica Courtney et al.   PLoS Genetics

Foxp1/4 control epithelial cell fate during lung development and regeneration through regulation of anterior gradient 2

(2012) S. Li et al.   DEVELOPMENT

Liver-Specific Disruption of the Murine Glucagon Receptor Produces  -Cell Hyperplasia: Evidence for a Circulating  -Cell Growth Factor

(2012) C. Longuet et al.   DIABETES

Glucagonocentric restructuring of diabetes: a pathophysiologic and therapeutic makeover

(2012) Roger H. Unger et al.   JOURNAL OF CLINICAL INVESTIGATION

In vivo reprogramming of Sox9+ cells in the liver to insulin-secreting ducts

(2012) A. Banga et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pancreas organogenesis: From bud to plexus to gland

(2011) Fong Cheng Pan et al.   DEVELOPMENTAL DYNAMICS

Glucagon Receptor Knockout Prevents Insulin-Deficient Type 1 Diabetes in Mice

(2011) Y. Lee et al.   DIABETES

Normal Glucagon Signaling and β-Cell Function After Near-Total α-Cell Ablation in Adult Mice

(2011) Fabrizio Thorel et al.   DIABETES

MafA and MafB Regulate Genes Critical to  -Cells in a Unique Temporal Manner

(2010) I. Artner et al.   DIABETES

Foxa1 and Foxa2 Maintain the Metabolic and Secretory Features of the Mature β-Cell

(2010) Nan Gao et al.   MOLECULAR ENDOCRINOLOGY

Conversion of adult pancreatic α-cells to β-cells after extreme β-cell loss

(2010) Fabrizio Thorel et al.   NATURE

Foxp1 is an essential transcriptional regulator for the generation of quiescent naive T cells during thymocyte development

(2009) X. Feng et al.   BLOOD

Gestational Diabetes Mellitus Resulting From Impaired  -Cell Compensation in the Absence of FoxM1, a Novel Downstream Effector of Placental Lactogen

(2009) H. Zhang et al.   DIABETES

Long-Term Inhibition of the Glucagon Receptor with a Monoclonal Antibody in Mice Causes Sustained Improvement in Glycemic Control, with Reversible  -Cell Hyperplasia and Hyperglucagonemia

(2009) W. Gu et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

pdx-1 function is specifically required in embryonic β cells to generate appropriate numbers of endocrine cell types and maintain glucose homeostasis

(2008) Maureen Gannon et al.   DEVELOPMENTAL BIOLOGY

 -Cell Proliferation, but Not Neogenesis, Following 60% Partial Pancreatectomy Is Impaired in the Absence of FoxM1

(2008) A. Ackermann Misfeldt et al.   DIABETES

Cooperative regulation in development by SMRT and FOXP1

(2008) K. Jepsen et al.   GENES & DEVELOPMENT

Dynamic regulation of Pdx1 enhancers by Foxa1 and Foxa2 is essential for pancreas development

(2008) N. Gao et al.   GENES & DEVELOPMENT

The Human Protein Atlas-a tool for pathology

(2008) F Pontén et al.   JOURNAL OF PATHOLOGY

In vivo reprogramming of adult pancreatic exocrine cells to β-cells

(2008) Qiao Zhou et al.   NATURE

Molecular and metabolic mechanisms of insulin resistance and β-cell failure in type 2 diabetes

(2008) Deborah M. Muoio et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Coordinated Actions of the Forkhead Protein Foxp1 and Hox Proteins in the Columnar Organization of Spinal Motor Neurons

(2008) David L. Rousso et al.   NEURON