Insulin and Glucagon Regulate Pancreatic α-Cell Proliferation

Targeting mTOR in renal cell carcinoma

(2010) Gary R. Hudes   CANCER

PI3K/Akt/FOXO3a pathway contributes to thrombopoietin-induced proliferation of primary megakaryocytes in vitro and in vivo via modulation of p27Kip1

(2010) Takafumi Nakao et al.   CELL CYCLE

Pancreatic β-cell overexpression of the glucagon receptor gene results in enhanced β-cell function and mass

(2009) Richard W. Gelling et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Synergistic effect of rapamycin and cisplatin in endometrial cancer cells

(2009) Victoria L. Bae-Jump et al.   CANCER

Critical Role for Hypothalamic mTOR Activity in Energy Balance

(2009) Hiroyuki Mori et al.   Cell Metabolism

Insulin Signaling in α Cells Modulates Glucagon Secretion In Vivo

(2009) Dan Kawamori et al.   Cell Metabolism

Rapamycin by itself and additively in combination with carboplatin inhibits the growth of ovarian cancer cells

(2009) Peter W. Schlosshauer et al.   GYNECOLOGIC ONCOLOGY

Effective Treatment of Advanced Colorectal Cancer by Rapamycin and 5-FU/Oxaliplatin Monitored by TIMP-1

(2009) Markus Wagner et al.   JOURNAL OF GASTROINTESTINAL SURGERY

Activation of PI3K/mTOR pathway occurs in most adult low-grade gliomas and predicts patient survival

(2009) Sean M. McBride et al.   JOURNAL OF NEURO-ONCOLOGY

Fully Human Monoclonal Antibodies Antagonizing the Glucagon Receptor Improve Glucose Homeostasis in Mice and Monkeys

(2009) H. Yan et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Glucose Effects on Beta-Cell Growth and Survival Require Activation of Insulin Receptors and Insulin Receptor Substrate 2

(2009) A. Assmann et al.   MOLECULAR AND CELLULAR BIOLOGY

GOLPH3 modulates mTOR signalling and rapamycin sensitivity in cancer

(2009) Kenneth L. Scott et al.   NATURE

Glutamate Is a Positive Autocrine Signal for Glucagon Release

(2008) Over Cabrera et al.   Cell Metabolism

SREBP Activity Is Regulated by mTORC1 and Contributes to Akt-Dependent Cell Growth

(2008) Thomas Porstmann et al.   Cell Metabolism

Selective versus Total Insulin Resistance: A Pathogenic Paradox

(2008) Michael S. Brown et al.   Cell Metabolism

Long-term hyperglucagonaemia induces early metabolic and renal phenotypes of Type 2 diabetes in mice

(2008) Xiao C. Li et al.   CLINICAL SCIENCE

Exendin-4 Improves Glycemic Control, Ameliorates Brain and Pancreatic Pathologies, and Extends Survival in a Mouse Model of Huntington's Disease

(2008) B. Martin et al.   DIABETES

Physiology of the pancreatic α-cell and glucagon secretion: role in glucose homeostasis and diabetes

(2008) Ivan Quesada et al.   JOURNAL OF ENDOCRINOLOGY

Expression of the GLP-1 Receptor in Mouse, Rat, and Human Pancreas

(2008) Ditte Tornehave et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

The Role of Incretins in Glucose Homeostasis and Diabetes Treatment

(2008) W. Kim et al.   PHARMACOLOGICAL REVIEWS

Effects of gastric inhibitory polypeptide (GIP) and related analogues on glucagon release at normo- and hyperglycaemia in Wistar rats and isolated islets

(2007) Roslyn S. Cassidy et al.   BIOLOGICAL CHEMISTRY