p63 controls cell migration and invasion by transcriptional regulation of MTSS1

p63 sustains self-renewal of mammary cancer stem cells through regulation of Sonic Hedgehog signaling

(2015) Elisa Maria Memmi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

EGF induces microRNAs that target suppressors of cell migration: miR-15b targetsMTSS1in breast cancer

(2015) Merav Kedmi et al.   Science Signaling

EGF induces microRNAs that target suppressors of cell migration: miR-15b targetsMTSS1in breast cancer

(2015) Merav Kedmi et al.   Science Signaling

p63-Mediated activation of the β-catenin/c-Myc signaling pathway stimulates esophageal squamous carcinoma cell invasion and metastasis

(2014) Kwang Bok Lee et al.   CANCER LETTERS

Crosstalk among p53 family members in cutaneous carcinoma

(2014) Caterina Missero et al.   EXPERIMENTAL DERMATOLOGY

How theTP53Family ProteinsTP63andTP73Contribute to Tumorigenesis: Regulators and Effectors

(2014) Eleonora Candi et al.   HUMAN MUTATION

ΔNp63 promotes stem cell activity in mammary gland development and basal-like breast cancer by enhancing Fzd7 expression and Wnt signalling

(2014) Rumela Chakrabarti et al.   NATURE CELL BIOLOGY

DRUGSURV: a resource for repositioning of approved and experimental drugs in oncology based on patient survival information

(2014) I Amelio et al.   Cell Death & Disease

MTSS1 is a metastasis driver in a subset of human melanomas

(2014) Kirsten D. Mertz et al.   Nature Communications

Collective Invasion in Breast Cancer Requires a Conserved Basal Epithelial Program

(2013) Kevin J. Cheung et al.   CELL

GLS2 is transcriptionally regulated by p73 and contributes to neuronal differentiation

(2013) Tania Velletri et al.   CELL CYCLE

p63 regulates glutaminase 2 expression

(2013) Giacobbe Arianna et al.   CELL CYCLE

FGFR2 signaling underlies p63 oncogenic function in squamous cell carcinoma

(2013) Matthew R. Ramsey et al.   JOURNAL OF CLINICAL INVESTIGATION

p63 is an alternative p53 repressor in melanoma that confers chemoresistance and a poor prognosis

(2013) Rubeta N. Matin et al.   JOURNAL OF EXPERIMENTAL MEDICINE

PPISURV: a novel bioinformatics tool for uncovering the hidden role of specific genes in cancer survival outcome

(2013) A V Antonov et al.   ONCOGENE

Caspase-1 is a novel target of p63 in tumor suppression

(2013) I Celardo et al.   Cell Death & Disease

ΔNp63α regulates Erk signaling via MKP3 to inhibit cancer metastasis

(2012) J Bergholz et al.   ONCOGENE

The Cul4A–DDB1 E3 ubiquitin ligase complex represses p73 transcriptional activity

(2012) M Malatesta et al.   ONCOGENE

Loss of p63 and its microRNA-205 target results in enhanced cell migration and metastasis in prostate cancer

(2012) P. Tucci et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

 Np63 Versatilely Regulates a Broad NF- B Gene Program and Promotes Squamous Epithelial Proliferation, Migration, and Inflammation

(2011) X. Yang et al.   CANCER RESEARCH

p63 is a suppressor of tumorigenesis and metastasis interacting with mutant p53

(2011) G Melino   CELL DEATH AND DIFFERENTIATION

The impact of Metastasis Suppressor-1, MTSS1, on oesophageal squamous cell carcinoma and its clinical significance

(2011) Fei Xie et al.   Journal of Translational Medicine

The p53 family: guardians of maternal reproduction

(2011) Arnold J. Levine et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Mtss1 regulates epidermal growth factor signaling in head and neck squamous carcinoma cells

(2011) J C Dawson et al.   ONCOGENE

MTSS1, a novel target of DNA methyltransferase 3B, functions as a tumor suppressor in hepatocellular carcinoma

(2011) H Fan et al.   ONCOGENE

The E3 ubiquitin ligase WWP1 regulates ΔNp63-dependent transcription through Lys63 linkages

(2010) Angelo Peschiaroli et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Overexpression of ΔNp63α induces a stem cell phenotype in MCF7 breast carcinoma cell line through the Notch pathway

(2010) Zhijian Du et al.   CANCER SCIENCE

ΔNp63 transcriptionally regulatesbrachyury, a gene with diverse roles in limb development, tumorigenesis and metastasis

(2010) Min Soon Cho et al.   CELL CYCLE

TAp63 suppresses metastasis through coordinate regulation of Dicer and miRNAs

(2010) Xiaohua Su et al.   NATURE

Loss of  Np63  Promotes Invasion of Urothelial Carcinomas via N-Cadherin/Src Homology and Collagen/Extracellular Signal-Regulated Kinase Pathway

(2009) H. Fukushima et al.   CANCER RESEARCH

Metastasis suppressor 1 (MTSS1) demonstrates prognostic value and anti-metastatic properties in breast cancer

(2009) Christian Parr et al.   EUROPEAN JOURNAL OF CANCER