ΔNp63α regulates Erk signaling via MKP3 to inhibit cancer metastasis

p63 is a suppressor of tumorigenesis and metastasis interacting with mutant p53

(2011) G Melino   CELL DEATH AND DIFFERENTIATION

ΔNp63α Is an Oncogene that Targets Chromatin Remodeler Lsh to Drive Skin Stem Cell Proliferation and Tumorigenesis

(2011) William M. Keyes et al.   Cell Stem Cell

Dual specificity phosphatase 6 (DUSP6) is an ETS-regulated negative feedback mediator of oncogenic ERK signaling in lung cancer cells

(2010) Zhenfeng Zhang et al.   CARCINOGENESIS

ΔNp63 is an ectodermal gatekeeper of epidermal morphogenesis

(2010) R Shalom-Feuerstein et al.   CELL DEATH AND DIFFERENTIATION

Role of ΔNp63γ in Epithelial to Mesenchymal Transition

(2010) Jaime Lindsay et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

ERK2 but Not ERK1 Induces Epithelial-to-Mesenchymal Transformation via DEF Motif-Dependent Signaling Events

(2010) Sejeong Shin et al.   MOLECULAR CELL

TAp63 suppresses metastasis through coordinate regulation of Dicer and miRNAs

(2010) Xiaohua Su et al.   NATURE

Heat-shock transcription factor HSF1 has a critical role in human epidermal growth factor receptor-2-induced cellular transformation and tumorigenesis

(2010) L Meng et al.   ONCOGENE

Down-Regulation of DUSP6 Expression in Lung Cancer

(2009) Koji Okudela et al.   AMERICAN JOURNAL OF PATHOLOGY

Orai1 and STIM1 Are Critical for Breast Tumor Cell Migration and Metastasis

(2009) Shengyu Yang et al.   CANCER CELL

Loss of  Np63  Promotes Invasion of Urothelial Carcinomas via N-Cadherin/Src Homology and Collagen/Extracellular Signal-Regulated Kinase Pathway

(2009) H. Fukushima et al.   CANCER RESEARCH

Mutant p53 Drives Invasion by Promoting Integrin Recycling

(2009) Patricia A.J. Muller et al.   CELL

A Mutant-p53/Smad Complex Opposes p63 to Empower TGFβ-Induced Metastasis

(2009) Maddalena Adorno et al.   CELL

ΔNp63α-dependent expression of Id-3 distinctively suppresses the invasiveness of human squamous cell carcinoma

(2009) Koichiro Higashikawa et al.   INTERNATIONAL JOURNAL OF CANCER

Erk1/2 MAP kinases are required for epidermal G2/M progression

(2009) Phillip A. Dumesic et al.   JOURNAL OF CELL BIOLOGY

Regulation of VDR by  Np63  is associated with inhibition of cell invasion

(2009) R. Kommagani et al.   JOURNAL OF CELL SCIENCE

Inhibition of the c-Abl–TAp63 pathway protects mouse oocytes from chemotherapy-induced death

(2009) Stefania Gonfloni et al.   NATURE MEDICINE

Negative-feedback regulation of FGF signalling by DUSP6/MKP-3 is driven by ERK1/2 and mediated by Ets factor binding to a conserved site within theDUSP6/MKP-3gene promoter

(2008) Maria Ekerot et al.   BIOCHEMICAL JOURNAL

p63 in epithelial development

(2008) E. Candi et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

DUSP6 (MKP3) Null Mice Show Enhanced ERK1/2 Phosphorylation at Baseline and Increased Myocyte Proliferation in the Heart Affecting Disease Susceptibility

(2008) Marjorie Maillet et al.   JOURNAL OF BIOLOGICAL CHEMISTRY