p63 is a suppressor of tumorigenesis and metastasis interacting with mutant p53

Distinct Expression Profiles of p63 Variants during Urothelial Development and Bladder Cancer Progression

(2011) Orit Karni-Schmidt et al.   AMERICAN JOURNAL OF PATHOLOGY

Comparison of proliferating cell nuclear antigen, thyroid transcription factor-1, Ki-67, p63, p53 and high–molecular weight cytokeratin expressions in papillary thyroid carcinoma, follicular carcinoma, and follicular adenoma

(2011) Ayca Tan et al.   Annals of Diagnostic Pathology

 Np63  Confers Tumor Cell Resistance to Cisplatin through the AKT1 Transcriptional Regulation

(2011) T. Sen et al.   CANCER RESEARCH

DNA Damage in Oocytes Induces a Switch of the Quality Control Factor TAp63α from Dimer to Tetramer

(2011) Gregor B. Deutsch et al.   CELL

Phospho-ΔNp63α is a key regulator of the cisplatin-induced microRNAome in cancer cells

(2011) Y Huang et al.   CELL DEATH AND DIFFERENTIATION

ΔNp63α Is an Oncogene that Targets Chromatin Remodeler Lsh to Drive Skin Stem Cell Proliferation and Tumorigenesis

(2011) William M. Keyes et al.   Cell Stem Cell

p53 and its mutants in tumor cell migration and invasion

(2011) Patricia A. J. Muller et al.   JOURNAL OF CELL BIOLOGY

p63, a Story of Mice and Men

(2011) Hans Vanbokhoven et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

p63 and p73 Isoform Expression in Non-small Cell Lung Cancer and Corresponding Morphological Normal Lung Tissue

(2011) Marco Lo Iacono et al.   Journal of Thoracic Oncology

D2-40/p63 defined lymph vessel invasion has additional prognostic value in highly proliferating operable node negative breast cancer patients

(2011) Einar Gudlaugsson et al.   MODERN PATHOLOGY

Hidden order revealed

(2011) Michael E. Flatté   Nature Physics

The p53 family: guardians of maternal reproduction

(2011) Arnold J. Levine et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Brothers in Arms Against Cancer

(2011) M. Leslie   SCIENCE

Optimal Immunohistochemical Markers For Distinguishing Lung Adenocarcinomas From Squamous Cell Carcinomas in Small Tumor Samples

(2010) Jefferson Terry et al.   AMERICAN JOURNAL OF SURGICAL PATHOLOGY

Subclassification of Non-small Cell Lung Carcinomas Lacking Morphologic Differentiation on Biopsy Specimens

(2010) Sanjay Mukhopadhyay et al.   AMERICAN JOURNAL OF SURGICAL PATHOLOGY

p63in Epithelial Survival, Germ Cell Surveillance, and Neoplasia

(2010) Christopher P. Crum et al.   Annual Review of Pathology-Mechanisms of Disease

Dominant negative (ΔN) p63α induces drug resistance in hepatocellular carcinoma by interference with apoptosis signaling pathways

(2010) Heiko M. Mundt et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The Integrin  v 3-5 Ligand MFG-E8 Is a p63/p73 Target Gene in Triple-Negative Breast Cancers but Exhibits Suppressive Functions in ER+ and erbB2+ Breast Cancers

(2010) C. Yang et al.   CANCER RESEARCH

A MicroRNA Targeting Dicer for Metastasis Control

(2010) Graziano Martello et al.   CELL

ΔNp63 is an ectodermal gatekeeper of epidermal morphogenesis

(2010) R Shalom-Feuerstein et al.   CELL DEATH AND DIFFERENTIATION

Role of ΔNp63γ in Epithelial to Mesenchymal Transition

(2010) Jaime Lindsay et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mammalian target of rapamycin regulates murine and human cell differentiation through STAT3/p63/Jagged/Notch cascade

(2010) Jianhui Ma et al.   JOURNAL OF CLINICAL INVESTIGATION

Assessment of malignant potential of oral submucous fibrosis through evaluation of p63, E-cadherin and CD105 expression

(2010) R. K. Das et al.   JOURNAL OF CLINICAL PATHOLOGY

TAp63 suppresses metastasis through coordinate regulation of Dicer and miRNAs

(2010) Xiaohua Su et al.   NATURE

Mutant p53 subverts p63 control over KLF4 expression in keratinocytes

(2010) N Cordani et al.   ONCOGENE

EMT, cancer stem cells and drug resistance: an emerging axis of evil in the war on cancer

(2010) A Singh et al.   ONCOGENE

c-Abl phosphorylation of ΔNp63α is critical for cell viability

(2010) M Yuan et al.   Cell Death & Disease

Precursor of prostate-specific antigen expression in prostatic intraepithelial neoplasia and adenocarcinoma: a study of 90 cases

(2009) David Hull et al.   BJU INTERNATIONAL

Clinical relevance of the putative stem cell marker p63 in breast cancer

(2009) L. Hanker et al.   BREAST CANCER RESEARCH AND TREATMENT

Aberrant Cytoplasmic Expression of p63 and Prostate Cancer Mortality

(2009) P. K. Dhillon et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Loss of  Np63  Promotes Invasion of Urothelial Carcinomas via N-Cadherin/Src Homology and Collagen/Extracellular Signal-Regulated Kinase Pathway

(2009) H. Fukushima et al.   CANCER RESEARCH

Expression of podoplanin, CD44, and p63 in squamous cell carcinoma of the lung

(2009) Yoshihisa Shimada et al.   CANCER SCIENCE

Mutant p53 Drives Invasion by Promoting Integrin Recycling

(2009) Patricia A.J. Muller et al.   CELL

A Mutant-p53/Smad Complex Opposes p63 to Empower TGFβ-Induced Metastasis

(2009) Maddalena Adorno et al.   CELL

Epithelial-Mesenchymal Transitions in Development and Disease

(2009) Jean Paul Thiery et al.   CELL

The α/β carboxy-terminal domains of p63 are required for skin and limb development. New insights from the Brdm2 mouse which is not a complete p63 knockout but expresses p63 γ-like proteins

(2009) S Wolff et al.   CELL DEATH AND DIFFERENTIATION

Conformational stability and activity of p73 require a second helix in the tetramerization domain

(2009) D Coutandin et al.   CELL DEATH AND DIFFERENTIATION

SKP-ing TAp63: Stem Cell Depletion, Senescence, and Premature Aging

(2009) Veronica G. Beaudry et al.   Cell Stem Cell

TAp63 Prevents Premature Aging by Promoting Adult Stem Cell Maintenance

(2009) Xiaohua Su et al.   Cell Stem Cell

ΔNp63α-dependent expression of Id-3 distinctively suppresses the invasiveness of human squamous cell carcinoma

(2009) Koichiro Higashikawa et al.   INTERNATIONAL JOURNAL OF CANCER

TAp63 induces senescence and suppresses tumorigenesis in vivo

(2009) Xuecui Guo et al.   NATURE CELL BIOLOGY

Inhibition of the c-Abl–TAp63 pathway protects mouse oocytes from chemotherapy-induced death

(2009) Stefania Gonfloni et al.   NATURE MEDICINE

Epidermal homeostasis: a balancing act of stem cells in the skin

(2009) Cédric Blanpain et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Identification and functional characterization of two new transcriptional variants of the human p63 gene

(2009) Marina Mangiulli et al.   NUCLEIC ACIDS RESEARCH

PUMA mediates EGFR tyrosine kinase inhibitor-induced apoptosis in head and neck cancer cells

(2009) Q Sun et al.   ONCOGENE

An Active Role of the ΔN Isoform of p63 in Regulating Basal Keratin Genes K5 and K14 and Directing Epidermal Cell Fate

(2009) Rose-Anne Romano et al.   PLoS One

One billion years of p53/p63/p73 evolution

(2009) V. A. Belyi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural evolution of p53, p63, and p73: Implication for heterotetramer formation

(2009) A. C. Joerger et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Comprehensive mutational analysis and mRNA isoform quantification ofTP63in normal and neoplastic human prostate cells

(2009) J. Kellogg Parsons et al.   PROSTATE

The HECT Family of E3 Ubiquitin Ligases: Multiple Players in Cancer Development

(2008) Francesca Bernassola et al.   CANCER CELL

Regulation of Dlx5 and Dlx6 gene expression by p63 is involved in EEC and SHFM congenital limb defects

(2008) N. Lo Iacono et al.   DEVELOPMENT

Overexpression of ΔNp63 in a human nasopharyngeal carcinoma cell line downregulates CKIs and enhances cell proliferation

(2008) Chi-Tai Chiang et al.   JOURNAL OF CELLULAR PHYSIOLOGY

ΔNp63 Is Essential for Epidermal Commitment of Embryonic Stem Cells

(2008) Alain Medawar et al.   PLoS One

Reciprocal Intraepithelial Interactions Between TP63 and Hedgehog Signaling Regulate Quiescence and Activation of Progenitor Elaboration by Mammary Stem Cells

(2008) Na Li et al.   STEM CELLS

Markers of Epithelial-Mesenchymal Transition and Epithelial Differentiation in Sarcomatoid Carcinoma: Utility in the Differential Diagnosis With Sarcoma

(2008) Justin M. M. Cates et al.   APPLIED IMMUNOHISTOCHEMISTRY & MOLECULAR MORPHOLOGY