p63 is an alternative p53 repressor in melanoma that confers chemoresistance and a poor prognosis

MDM4 is a key therapeutic target in cutaneous melanoma

(2012) Agnieszka Gembarska et al.   NATURE MEDICINE

P53 in human melanoma fails to regulate target genes associated with apoptosis and the cell cycle and may contribute to proliferation

(2011) Kelly A Avery-Kiejda et al.   BMC CANCER

The melanoma ‘epidemic’, a dermatopathologist's perspective

(2011) Earl J. Glusac   JOURNAL OF CUTANEOUS PATHOLOGY

p53 Rescue through HDM2 Antagonism Suppresses Melanoma Growth and Potentiates MEK Inhibition

(2011) Zhenyu Ji et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Analysis of the functional integrity of the p53 tumor-suppressor gene in malignant melanoma

(2011) Andreas Knopf et al.   MELANOMA RESEARCH

E2F1-dependent oncogenic addiction of melanoma cells to MDM2

(2011) M Verhaegen et al.   ONCOGENE

SPARC functions as an anti-stress factor by inactivating p53 through Akt-mediated MDM2 phosphorylation to promote melanoma cell survival

(2011) N Fenouille et al.   ONCOGENE

High-Level Expression of Wild-Type p53 in Melanoma Cells is Frequently Associated with Inactivity in p53 Reporter Gene Assays

(2011) Roland Houben et al.   PLoS One

Adaptation of cancer cells from different entities to the MDM2 inhibitor nutlin-3 results in the emergence of p53-mutated multi-drug-resistant cancer cells

(2011) M Michaelis et al.   Cell Death & Disease

Interference with the p53 family network contributes to the gain of oncogenic function of mutant p53 in hepatocellular carcinoma

(2010) Tobias Schilling et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Dominant negative (ΔN) p63α induces drug resistance in hepatocellular carcinoma by interference with apoptosis signaling pathways

(2010) Heiko M. Mundt et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

p53 inactivation by MDM2 and MDMX negative feedback loops in testicular germ cell tumors

(2010) Baozong Li et al.   CELL CYCLE

CD10, p63 and CD99 expression in the differential diagnosis of atypical fibroxanthoma, spindle cell squamous cell carcinoma and desmoplastic melanoma

(2010) William A. Kanner et al.   JOURNAL OF CUTANEOUS PATHOLOGY

Identification of the Spiro(oxindole-3,3′-thiazolidine)-Based Derivatives as Potential p53 Activity Modulators

(2010) Isabel Gomez-Monterrey et al.   JOURNAL OF MEDICINAL CHEMISTRY

Aberrant Cytoplasmic Expression of p63 and Prostate Cancer Mortality

(2009) P. K. Dhillon et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

MDM4 (MDMX) localizes at the mitochondria and facilitates the p53-mediated intrinsic-apoptotic pathway

(2009) Francesca Mancini et al.   EMBO JOURNAL

Redox-Dependent Translocation of p53 to Mitochondria or Nucleus in Human Melanocytes after UVA- and UVB-Induced Apoptosis

(2009) Petra K. Wäster et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Increased expression of p73Δex2 transcript in uveal melanoma with loss of chromosome 1p

(2009) Emine Kilic et al.   MELANOMA RESEARCH

Identification and functional characterization of two new transcriptional variants of the human p63 gene

(2009) Marina Mangiulli et al.   NUCLEIC ACIDS RESEARCH

Hsp70 molecular chaperones are required to support p53 tumor suppressor activity under stress conditions

(2009) D Walerych et al.   ONCOGENE

The expression of p63 and p53 in keratoacanthoma and intraepidermal and invasive neoplasms of the skin

(2009) Damlanur Sakiz et al.   PATHOLOGY RESEARCH AND PRACTICE

p63 Expression in Olfactory Neuroblastoma and Other Small Cell Tumors of the Sinonasal Tract

(2008) T. David Bourne et al.   AMERICAN JOURNAL OF CLINICAL PATHOLOGY

Immunohistochemical Distinction of Cutaneous Spindle Cell Carcinoma

(2008) Michael B Morgan et al.   AMERICAN JOURNAL OF DERMATOPATHOLOGY

Role of Cytogenetics in Management of Uveal Melanoma

(2008) Jerry A. Shields   ARCHIVES OF OPHTHALMOLOGY

Uveal vs. cutaneous melanoma. Origins and causes of the differences

(2008) Carolina Belmar-Lopez et al.   Clinical & Translational Oncology

Small Molecular Weight Variants of p53 Are Expressed in Human Melanoma Cells and Are Induced by the DNA-Damaging Agent Cisplatin

(2008) K. A. Avery-Kiejda et al.   CLINICAL CANCER RESEARCH

Apoptosis-associated mitochondrial outer membrane permeabilization assays

(2008) Damien Arnoult   METHODS

Transcriptional control of human p53-regulated genes

(2008) Todd Riley et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The biology and management of uveal melanoma

(2008) Takami Sato et al.   Current Oncology Reports

Effect of Storage on p63 Immunohistochemistry

(2008) Holly N. Burford et al.   APPLIED IMMUNOHISTOCHEMISTRY & MOLECULAR MORPHOLOGY