Metabolomics – the complementary field in systems biology: a review on obesity and type 2 diabetes
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Title
Metabolomics – the complementary field in systems biology: a review on obesity and type 2 diabetes
Authors
Keywords
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Journal
Molecular BioSystems
Volume 11, Issue 7, Pages 1742-1774
Publisher
Royal Society of Chemistry (RSC)
Online
2015-04-17
DOI
10.1039/c5mb00158g
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Note: Only part of the references are listed.- Choline: An Important Micronutrient for Maximal Endurance-Exercise Performance?
- (2016) Jason T. Penry et al. INTERNATIONAL JOURNAL OF SPORT NUTRITION AND EXERCISE METABOLISM
- Amelioration of Mitochondrial Dysfunction-Induced Insulin Resistance in Differentiated 3T3-L1 Adipocytes via Inhibition of NF-κB Pathways
- (2014) Mohamad Bakar et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
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- (2013) Monireh Dashty CLINICAL BIOCHEMISTRY
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- (2013) C. Menni et al. DIABETES
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- (2013) Larysa V. Yuzefovych et al. ENDOCRINOLOGY
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- (2013) Fengguo Xu et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
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- (2013) A. Dessì et al. JOURNAL OF OBSTETRICS AND GYNAECOLOGY
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- (2013) Emily G. Armitage et al. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
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- (2013) Robert A Koeth et al. NATURE MEDICINE
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- (2013) Rebecca C. Schugar et al. PLoS One
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- (2013) Vivian C Luft et al. Diabetology & Metabolic Syndrome
- Diabetic ketoacidosis: not always due to type 1 diabetes
- (2013) S. Misra et al. BMJ-British Medical Journal
- Perinatal programming of obesity: an introduction to the topic
- (2013) Catalina Pico et al. Frontiers in Physiology
- Metabolomics in human type 2 diabetes research
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- (2012) C. Bueschl et al. ANALYTICAL AND BIOANALYTICAL CHEMISTRY
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- (2012) L.M. Berends et al. BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM
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- (2011) Maren Pflueger et al. DIABETES
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- LC-MS-based metabolomics
- (2011) Bin Zhou et al. Molecular BioSystems
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- (2011) Zeneng Wang et al. NATURE
- Human metabolic individuality in biomedical and pharmaceutical research
- (2011) Karsten Suhre et al. NATURE
- N6-Methyladenosine in nuclear RNA is a major substrate of the obesity-associated FTO
- (2011) Guifang Jia et al. Nature Chemical Biology
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- (2011) Karl Burgess et al. RAPID COMMUNICATIONS IN MASS SPECTROMETRY
- Obesity, insulin resistance and free fatty acids
- (2011) Guenther Boden Current Opinion in Endocrinology Diabetes and Obesity
- Integration of metabolomics in heart disease and diabetes research: current achievements and future outlook
- (2011) Warwick B Dunn et al. Bioanalysis
- Sulwon Lecture 2009: The Search for Genetic Risk Factors of Type 2 Diabetes Mellitus
- (2011) Kyong Soo Park Diabetes & Metabolism Journal
- ATP synthesis is impaired in isolated mitochondria from myotubes established from type 2 diabetic subjects
- (2010) Ariane D. Minet et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Systems level studies of mammalian metabolomes: the roles of mass spectrometry and nuclear magnetic resonance spectroscopy
- (2010) Warwick B. Dunn et al. CHEMICAL SOCIETY REVIEWS
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- (2010) Ferdinando Giacco et al. CIRCULATION RESEARCH
- Taurine in cardiovascular disease
- (2010) Anthony Zulli CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE
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- (2010) G. Musso et al. DIABETES CARE
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- (2010) Ines Pagel-Langenickel et al. ENDOCRINE REVIEWS
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- (2010) Walter E. Gall et al. PLoS One
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- Unknown
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- Quantitative metabolomics using NMR
- (2008) David S. Wishart TRAC-TRENDS IN ANALYTICAL CHEMISTRY
- Genetics Meets Metabolomics: A Genome-Wide Association Study of Metabolite Profiles in Human Serum
- (2008) Christian Gieger et al. PLoS Genetics
- Genetic Networks of Liver Metabolism Revealed by Integration of Metabolic and Transcriptional Profiling
- (2008) Christine T. Ferrara et al. PLoS Genetics
- Global Transcript Profiles of Fat in Monozygotic Twins Discordant for BMI: Pathways behind Acquired Obesity
- (2008) Kirsi H Pietiläinen et al. PLOS MEDICINE
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