Inside the Endometrial Cell Signaling Subway: Mind the Gap(s)

Endometrial stem/progenitor cells and their role in the pathogenesis of endometriosis

(2018) Fiona L. Cousins et al.   BEST PRACTICE & RESEARCH CLINICAL OBSTETRICS & GYNAECOLOGY

RBPJ mediates uterine repair in the mouse and is reduced in women with recurrent pregnancy loss

(2018) Michael R. Strug et al.   FASEB JOURNAL

Analysis of long non-coding RNA expression profiles using RNA sequencing in ovarian endometriosis

(2018) Ding Cui et al.   GENE

In vitro evidence that platelet-rich plasma stimulates cellular processes involved in endometrial regeneration

(2018) Lusine Aghajanova et al.   JOURNAL OF ASSISTED REPRODUCTION AND GENETICS

Androgens and endometrium: New insights and new targets

(2018) Ioannis Simitsidellis et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Reproductive endocrinology: Hypoxia in endometrial repair

(2018) Claire Greenhill   Nature Reviews Endocrinology

Human menstrual blood–derived stem cells promote the repair of impaired endometrial stromal cells by activating the p38 MAPK and AKT signaling pathways

(2018) Haiyan Zhu et al.   Reproductive Biology

Hypoxia and hypoxia inducible factor-1α are required for normal endometrial repair during menstruation

(2018) Jacqueline A. Maybin et al.   Nature Communications

Dynamic expression of PGRMC1 and SERBP1 in human endometrium: an implication in the human decidualization process

(2017) Stefania Salsano et al.   FERTILITY AND STERILITY

Transcriptome landscape of long intergenic non-coding RNAs in endometrial cancer

(2017) Bei Jun Chen et al.   GYNECOLOGIC ONCOLOGY

High-quality human preimplantation embryos actively influence endometrial stromal cell migration

(2017) R. P. Berkhout et al.   JOURNAL OF ASSISTED REPRODUCTION AND GENETICS

Progesterone-Induced miR-152 Inhibits the Proliferation of Endometrial Epithelial Cells by Downregulating WNT-1

(2017) Li Nie et al.   Reproductive Sciences

Aberrant Akt Activation During Implantation Window in Infertile Women With Intramural Uterine Fibroids

(2017) Annu Makker et al.   Reproductive Sciences

Endometrium and steroids, a pathologic overview

(2017) Francisca Plaza-Parrochia et al.   STEROIDS

Molecular regulation and role of angiogenesis in reproduction

(2017) Momchil Rizov et al.   Taiwanese Journal of Obstetrics & Gynecology

Pericyte-expressed Tie2 controls angiogenesis and vessel maturation

(2017) Martin Teichert et al.   Nature Communications

Regulation of the PI3K/Akt pathway during decidualization of endometrial stromal cells

(2017) François Fabi et al.   PLoS One

Secretome of in vitro cultured human embryos contains extracellular vesicles that are uptaken by the maternal side

(2017) Elisa Giacomini et al.   Scientific Reports

Meta-signature of human endometrial receptivity: a meta-analysis and validation study of transcriptomic biomarkers

(2017) Signe Altmäe et al.   Scientific Reports

Progesterone-Regulated Endometrial Factors Controlling Implantation

(2016) Arpita S. Bhurke et al.   AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY

Human Endometrial Exosomes Contain Hormone-Specific Cargo Modulating Trophoblast Adhesive Capacity: Insights into Endometrial-Embryo Interactions1

(2016) David W. Greening et al.   BIOLOGY OF REPRODUCTION

Androgens regulate scarless repair of the endometrial “wound” in a mouse model of menstruation

(2016) Fiona L. Cousins et al.   FASEB JOURNAL

The role of decidual cells in uterine hemostasis, menstruation, inflammation, adverse pregnancy outcomes and abnormal uterine bleeding

(2016) Frederick Schatz et al.   HUMAN REPRODUCTION UPDATE

Decidual macrophages: key regulators of vascular remodeling in human pregnancy

(2016) Gendie E. Lash et al.   JOURNAL OF LEUKOCYTE BIOLOGY

What's new in estrogen receptor action in the female reproductive tract

(2016) Sylvia C Hewitt et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

Growth factor induced proliferation, migration, and lumen formation of rat endometrial epithelial cells in vitro

(2016) Md. Rashedul ISLAM et al.   JOURNAL OF REPRODUCTION AND DEVELOPMENT

The G protein-coupled estrogen receptor as a modulator of neoplastic transformation

(2016) Damian Jacenik et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Fertile ground: human endometrial programming and lessons in health and disease

(2016) Jemma Evans et al.   Nature Reviews Endocrinology

Estrogen signaling in the proliferative endometrium: implications in endometriosis

(2016) Rita de Cássia Pereira da Costa e Silva et al.   Revista da Associacao Medica Brasileira

Non-coding RNA LINC00473 mediates decidualization of human endometrial stromal cells in response to cAMP signaling

(2016) Xiao-Huan Liang et al.   Scientific Reports

Cyclic Stretch Augments Production of Neutrophil Chemokines, Matrix Metalloproteinases, and Activin A in Human Endometrial Stromal Cells

(2015) Gentaro Izumi et al.   AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY

Endometrial CRISP3 Is Regulated Throughout the Mouse Estrous and Human Menstrual Cycle and Facilitates Adhesion and Proliferation of Endometrial Epithelial Cells1

(2015) Jemma Evans et al.   BIOLOGY OF REPRODUCTION

Menstrual physiology: implications for endometrial pathology and beyond

(2015) Jacqueline A. Maybin et al.   HUMAN REPRODUCTION UPDATE

Rac1 Regulates Endometrial Secretory Function to Control Placental Development

(2015) Juanmahel Davila et al.   PLoS Genetics

Participation of WNT andβ-Catenin in Physiological and Pathological Endometrial Changes: Association with Angiogenesis

(2015) Jolanta Kiewisz et al.   Biomed Research International

Profiling of Selected MicroRNAs in Proliferative Eutopic Endometrium of Women with Ovarian Endometriosis

(2015) P. Laudanski et al.   Biomed Research International

Cyclic Decidualization of the Human Endometrium in Reproductive Health and Failure

(2014) Birgit Gellersen et al.   ENDOCRINE REVIEWS

Activated AKT Pathway Promotes Establishment of Endometriosis

(2014) Tae Hoon Kim et al.   ENDOCRINOLOGY

ROS Are Critical for Endometrial Breakdown via NF-κB–COX-2 Signaling in a Female Mouse Menstrual-Like Model

(2014) Bin Wu et al.   ENDOCRINOLOGY

Endometrial stromal cells and decidualized stromal cells: Origins, transformation and functions

(2014) Ha Zhu et al.   GENE

Deciphering the proteomic signature of human endometrial receptivity

(2014) T. Garrido-Gomez et al.   HUMAN REPRODUCTION

Increased angiogenic factor secretion by decidual natural killer cells from pregnancies with high uterine artery resistance alters trophoblast function

(2014) A. E. Wallace et al.   HUMAN REPRODUCTION

Role of nuclear progesterone receptor isoforms in uterine pathophysiology

(2014) B. Patel et al.   HUMAN REPRODUCTION UPDATE

Role of uterine stromal-epithelial crosstalk in embryo implantation

(2014) Alison M. Hantak et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY

Oestrogen-induced angiogenesis promotes adenomyosis by activating the Slug-VEGF axis in endometrial epithelial cells

(2014) Tze-Sing Huang et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Regulation of decidualization and angiogenesis in the human endometrium: Mini review

(2014) Hidetaka Okada et al.   JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH

Estrogen biology: New insights into GPER function and clinical opportunities

(2014) Eric R. Prossnitz et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Galectin-7 is important for normal uterine repair following menstruation

(2014) J. Evans et al.   MOLECULAR HUMAN REPRODUCTION

GPER Mediates Estrogen-Induced Signaling and Proliferation in Human Breast Epithelial Cells and Normal and Malignant Breast

(2014) Allison L. Scaling et al.   Hormones & Cancer

Neutrophil-Derived Cytokines: Facts Beyond Expression

(2014) Cristina Tecchio et al.   Frontiers in Immunology

Vascular endothelial growth factor C is increased in endometrium and promotes endothelial functions, vascular permeability and angiogenesis and growth of endometriosis

(2013) Hui Xu et al.   ANGIOGENESIS

Human Endometrial Stromal Cell-Trophoblast Interactions: Mutual Stimulation of Chemotactic Migration and Promigratory Roles of Cell Surface Molecules CD82 and CEACAM11

(2013) Birgit Gellersen et al.   BIOLOGY OF REPRODUCTION

VEGF-A regulated by progesterone governs uterine angiogenesis and vascular remodelling during pregnancy

(2013) Minah Kim et al.   EMBO Molecular Medicine

Divergent regulation of angiopoietin-1, angiopoietin-2, and vascular endothelial growth factor by hypoxia and female sex steroids in human endometrial stromal cells

(2013) Tomoko Tsuzuki et al.   European Journal of Obstetrics & Gynecology and Reproductive Biology

G-protein-coupled receptor 30/adenylyl cyclase/protein kinase A pathway is involved in estradiol 17ß-d-glucuronide-induced cholestasis

(2013) Andrés E. Zucchetti et al.   HEPATOLOGY

ERβ-dependent effects on uterine endothelial cells are cell specific and mediated via Sp1

(2013) Erin Greaves et al.   HUMAN REPRODUCTION

The role of progesterone in implantation and trophoblast invasion

(2013) Melinda Halasz et al.   JOURNAL OF REPRODUCTIVE IMMUNOLOGY

The role of FOXO1 in the decidual transformation of the endometrium and early pregnancy

(2013) Takeshi Kajihara et al.   Medical Molecular Morphology

Control of Human Endometrial Stromal Cell Motility by PDGF-BB, HB-EGF and Trophoblast-Secreted Factors

(2013) Maren Schwenke et al.   PLoS One

PGRMC1 and PGRMC2 in uterine physiology and disease

(2013) James K. Pru et al.   Frontiers in Neuroscience

Wnt6 Is Essential for Stromal Cell Proliferation During Decidualization in Mice1

(2012) Qiang Wang et al.   BIOLOGY OF REPRODUCTION

Dynamic Regulation of Wnt7a Expression in the Primate Endometrium: Implications for Postmenstrual Regeneration and Secretory Transformation

(2012) Xiujun Fan et al.   ENDOCRINOLOGY

WNT4 Acts Downstream of BMP2 and Functions via β-Catenin Signaling Pathway to Regulate Human Endometrial Stromal Cell Differentiation

(2012) Quanxi Li et al.   ENDOCRINOLOGY

Stimulation of GPR30 Increases Release of EMMPRIN-Containing Microvesicles in Human Uterine Epithelial Cells

(2012) Lindsey A. Burnett et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Regulation of Human Endometrial Stromal Proliferation and Differentiation by C/EBPβ Involves Cyclin E-cdk2 and STAT3

(2012) Wei Wang et al.   MOLECULAR ENDOCRINOLOGY

Stromal-to-Epithelial Transition during Postpartum Endometrial Regeneration

(2012) Cheng-Chiu Huang et al.   PLoS One

G Protein-Coupled Estrogen Receptor (GPER) Expression in Normal and Abnormal Endometrium

(2012) Beth J. Plante et al.   Reproductive Sciences

EMMPRIN Is Secreted by Human Uterine Epithelial Cells in Microvesicles and Stimulates Metalloproteinase Production by Human Uterine Fibroblast Cells

(2012) A. G. Braundmeier et al.   Reproductive Sciences

Steroid regulation of menstrual bleeding and endometrial repair

(2012) Jacqueline A. Maybin et al.   REVIEWS IN ENDOCRINE & METABOLIC DISORDERS

Endometrial regeneration and endometrial stem/progenitor cells

(2012) Caroline E. Gargett et al.   REVIEWS IN ENDOCRINE & METABOLIC DISORDERS

Endometrial haemostasis and menstruation

(2012) Joanna Davies et al.   REVIEWS IN ENDOCRINE & METABOLIC DISORDERS

Mesenchymal-to-Epithelial Transition Contributes to Endometrial Regeneration Following Natural and Artificial Decidualization

(2012) Amanda L. Patterson et al.   STEM CELLS AND DEVELOPMENT

Extracellular Matrix Dynamics in Scar-Free Endometrial Repair: Perspectives from Mouse In Vivo and Human In Vitro Studies

(2011) J. Evans et al.   BIOLOGY OF REPRODUCTION

CXCL12-CXCR4 Axis in Angiogenesis, Metastasis and Stem Cell Mobilization

(2011) S. Liekens et al.   CURRENT PHARMACEUTICAL DESIGN

Endometrial LGR7 expression during menstrual cycle

(2011) Maria Rosaria Campitiello et al.   FERTILITY AND STERILITY

Normal endometrial stromal cells regulate survival and apoptosis signaling through PI3K/AKt/Survivin pathway in endometrial adenocarcinoma cells in vitro

(2011) Min Shi et al.   GYNECOLOGIC ONCOLOGY

Abnormal activation of Ras/Raf/MAPK and RhoA/ROCKII signalling pathways in eutopic endometrial stromal cells of patients with endometriosis

(2011) I.Y. Yotova et al.   HUMAN REPRODUCTION

Trophoblast-derived chemokine CXCL12 promotes CXCR4 expression and invasion of human first-trimester decidual stromal cells

(2011) L. Ren et al.   HUMAN REPRODUCTION

Transcriptome analysis reveals dialogues between human trophectoderm and endometrial cells during the implantation period

(2011) D. Haouzi et al.   HUMAN REPRODUCTION

The Regulation of Vascular Endothelial Growth Factor by Hypoxia and Prostaglandin F2αduring Human Endometrial Repair

(2011) Jacqueline A. Maybin et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Mitochondrial reactive oxygen species drive proinflammatory cytokine production: Figure 1.

(2011) Edwina Naik et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Computational modeling on the recognition of the HRE motif by HIF-1: molecular docking and molecular dynamics studies

(2011) Pandian Sokkar et al.   JOURNAL OF MOLECULAR MODELING

Vessel remodelling, pregnancy hormones and extravillous trophoblast function

(2011) Jessie Z.-J. Chen et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Interaction between sex hormones and WNT/β-catenin signal transduction in endometrial physiology and disease

(2011) Paul H. van der Horst et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Expansion of human trophoblastic spheroids is promoted by decidualized endometrial stromal cells and enhanced by heparin-binding epidermal growth factor-like growth factor and interleukin-1β

(2011) Marina Gonzalez et al.   MOLECULAR HUMAN REPRODUCTION

Decidual Cell Polyploidization Necessitates Mitochondrial Activity

(2011) Xinghong Ma et al.   PLoS One

The Antiproliferative Action of Progesterone in Uterine Epithelium Is Mediated by Hand2

(2011) Q. Li et al.   SCIENCE

The Expression of Wnt4 Is Regulated by Estrogen via an Estrogen Receptor Alpha-dependent Pathway in Rat Pituitary Growth Hormone-producing Cells

(2010) Takashi Miyakoshi et al.   ACTA HISTOCHEMICA ET CYTOCHEMICA

Human Endometrial Stromal Cell Rho GTPases Have Opposing Roles in Regulating Focal Adhesion Turnover and Embryo Invasion In Vitro1

(2010) Seema Grewal et al.   BIOLOGY OF REPRODUCTION

Forkhead Transcription Factor FOXO1 is a Direct Target of Progestin to Inhibit Endometrial Epithelial Cell Growth

(2010) S. Kyo et al.   CLINICAL CANCER RESEARCH

Concentrations of stromal cell-derived factor-1 and vascular endothelial growth factor in relation to the diameter of human follicles

(2010) Akemi Nishigaki et al.   FERTILITY AND STERILITY

Estrogen induces stromal cell-derived factor 1 (SDF-1/CXCL12) production in human endometrial stromal cells: a possible role of endometrial epithelial cell growth

(2010) Akihiro Tsutsumi et al.   FERTILITY AND STERILITY

Invasiveness of human endometrial stromal cells is promoted by decidualization and by trophoblast-derived signals

(2010) B. Gellersen et al.   HUMAN REPRODUCTION

MUC1 as a Discriminator between Endometrium from Fertile and Infertile Patients with PCOS and Endometriosis

(2010) L. Margarit et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Death effector domain–containing protein (DEDD) is required for uterine decidualization during early pregnancy in mice

(2010) Mayumi Mori et al.   JOURNAL OF CLINICAL INVESTIGATION

Wnt Signalling in Implantation, Decidualisation and Placental Differentiation – Review

(2010) S. Sonderegger et al.   PLACENTA

Uterine epithelial estrogen receptor   is dispensable for proliferation but essential for complete biological and biochemical responses

(2010) W. Winuthayanon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Endometrial Decidualization: Of Mice and Men

(2010) Cyril Ramathal et al.   SEMINARS IN REPRODUCTIVE MEDICINE

Vasculogenesis and angiogenesis in the endometrium during menstrual cycle and implantation

(2009) Ramazan Demir et al.   ACTA HISTOCHEMICA

Wnt Genes in the Mouse Uterus: Potential Regulation of Implantation1

(2009) Kanako Hayashi et al.   BIOLOGY OF REPRODUCTION

Estrogenic G protein-coupled receptor 30 signaling is involved in regulation of endometrial carcinoma by promoting proliferation, invasion potential, and interleukin-6 secretion via the MEK/ERK mitogen-activated protein kinase pathway

(2009) Yin-Yan He et al.   CANCER SCIENCE

Wnt signaling pathways meet Rho GTPases

(2009) K. Schlessinger et al.   GENES & DEVELOPMENT

Excessive ovarian stimulation up-regulates the Wnt-signaling molecule DKK1 in human endometrium and may affect implantation: an in vitro co-culture study

(2009) Y. Liu et al.   HUMAN REPRODUCTION

Estrogen-mediated Regulation of Igf1 Transcription and Uterine Growth Involves Direct Binding of Estrogen Receptor α to Estrogen-responsive Elements

(2009) Sylvia C. Hewitt et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Roles of Estrogen and Progesterone in Endometrial Hemodynamics and Vascular Endothelial Growth Factor Production

(2009) Lily Wen et al.   Journal of the Chinese Medical Association

Cell Migration Is Regulated by Platelet-Derived Growth Factor Receptor Endocytosis

(2009) K. Kawada et al.   MOLECULAR AND CELLULAR BIOLOGY

MicroRNA expression profiling of eutopic secretory endometrium in women with versus without endometriosis

(2009) R.O. Burney et al.   MOLECULAR HUMAN REPRODUCTION

Diverse functions of HBEGF during pregnancy

(2009) Philip Jessmon et al.   MOLECULAR REPRODUCTION AND DEVELOPMENT

Mechanisms of matrix metalloproteinase-2 (mmp-2) transcriptional repression by progesterone in jar choriocarcinoma cells

(2009) Shlomit Goldman et al.   Reproductive Biology and Endocrinology

Estrogen-induced stromal cell-derived factor-1 (SDF-1/Cxcl12) expression is repressed by progesterone and by Selective Estrogen Receptor Modulators via estrogen receptor α in rat uterine cells and tissues

(2009) Lindsay Glace et al.   STEROIDS

Involvement of human decidual cell-expressed tissue factor in uterine hemostasis and abruption

(2009) C.J. Lockwood et al.   THROMBOSIS RESEARCH

Wnt5a Is Required for Endothelial Differentiation of Embryonic Stem Cells and Vascularization via Pathways Involving Both Wnt/β-Catenin and Protein Kinase Cα

(2008) Dong-Hwa Yang et al.   CIRCULATION RESEARCH

Inactivation of nuclear Wnt- -catenin signaling limits blastocyst competency for implantation

(2008) H. Xie et al.   DEVELOPMENT

Molecular and Cellular Mechanisms for Differentiation and Regeneration of the Uterine Endometrium

(2008) Tetsuo MARUYAMA et al.   ENDOCRINE JOURNAL

Autocrine stimulation of IGF1 in estrogen-induced growth of endometrial carcinoma cells: involvement of the mitogen-activated protein kinase pathway followed by up-regulation of cyclin D1 and cyclin E

(2008) Hiroyasu Kashima et al.   ENDOCRINE-RELATED CANCER

A New Role for Activin in Endometrial Repair after Menses

(2008) Tu'uhevaha J. Kaitu'u-Lino et al.   ENDOCRINOLOGY

VEGF blockade inhibits angiogenesis and reepithelialization of endometrium

(2008) Xiujun Fan et al.   FASEB JOURNAL

Production of Interleukin-1α by Human Endometrial Stromal Cells Is Triggered during Menses and Dysfunctional Bleeding and Is Induced in Culture by Epithelial Interleukin-1α Released upon Ovarian Steroids Withdrawal

(2008) Chrystel M. Pretto et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Decreased Expression of Angiogenin in the Eutopic Endometrium from Women with Advanced Stage Endometriosis

(2008) Sung Hoon Kim et al.   JOURNAL OF KOREAN MEDICAL SCIENCE

Hormone and growth factor signaling in endometrial renewal: Role of stem/progenitor cells

(2008) Caroline E. Gargett et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Secreted Frizzled-Related Protein 4 Regulates Two Wnt7a Signaling Pathways and Inhibits Proliferation in Endometrial Cancer Cells

(2008) K. S. Carmon et al.   MOLECULAR CANCER RESEARCH

Implantation of the human embryo requires Rac1-dependent endometrial stromal cell migration

(2008) S. Grewal et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA