Role of nuclear progesterone receptor isoforms in uterine pathophysiology

Endometrial Intraepithelial Neoplasia

(2014) Richard A. Owings et al.   ARCHIVES OF PATHOLOGY & LABORATORY MEDICINE

Epigenetic Modification Restores Functional PR Expression in Endometrial Cancer Cells

(2014) Shujie Yang et al.   CURRENT PHARMACEUTICAL DESIGN

Long-term treatment of uterine fibroids with ulipristal acetate☆

(2014) Jacques Donnez et al.   FERTILITY AND STERILITY

Risk of endometrial, ovarian and breast cancer in women with polycystic ovary syndrome: a systematic review and meta-analysis

(2014) John A. Barry et al.   HUMAN REPRODUCTION UPDATE

Increased progesterone receptor A expression in labouring human myometrium is associated with decreased promoter occupancy by the histone demethylase JARID1A

(2014) S. Y. Chai et al.   MOLECULAR HUMAN REPRODUCTION

CDC2 Mediates Progestin Initiated Endometrial Stromal Cell Proliferation: A PR Signaling to Gene Expression Independently of Its Binding to Chromatin

(2014) Griselda Vallejo et al.   PLoS One

Progesterone Signaling Inhibits Cervical Carcinogenesis in Mice

(2013) Young A Yoo et al.   AMERICAN JOURNAL OF PATHOLOGY

The PRB-dependent FOXO1/IGFBP-1 axis is essential for progestin to inhibit endometrial epithelial growth

(2013) Mitsuhiro Nakamura et al.   CANCER LETTERS

Progesterone Action in Endometrial Cancer, Endometriosis, Uterine Fibroids, and Breast Cancer

(2013) J. Julie Kim et al.   ENDOCRINE REVIEWS

Hormone receptor loss in endometrial carcinoma curettage predicts lymph node metastasis and poor outcome in prospective multicentre trial

(2013) Jone Trovik et al.   EUROPEAN JOURNAL OF CANCER

Retrospective analysis of prognostic variables and clinical outcomes in surgically staged intermediate risk endometrial carcinoma

(2013) Gong-yi Zhang et al.   European Journal of Obstetrics & Gynecology and Reproductive Biology

Histological and immunohistochemical profiles predict lymph node status in women with low-intermediate risk endometrial cancer

(2013) Marcos Ballester et al.   GYNECOLOGIC ONCOLOGY

Pathologic features associated with resolution of complex atypical hyperplasia and grade 1 endometrial adenocarcinoma after progestin therapy

(2013) Camille C. Gunderson et al.   GYNECOLOGIC ONCOLOGY

Post-translational modifications of the progesterone receptors

(2013) Hany A. Abdel-Hafiz et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Mifepristone–Misoprostol Dosing Interval and Effect on Induction Abortion Times

(2013) Kate A. Shaw et al.   OBSTETRICS AND GYNECOLOGY

Ulipristal Acetate: a Novel Option for the Medical Management of Symptomatic Uterine Fibroids

(2012) Vikram S. Talaulikar et al.   ADVANCES IN THERAPY

Proteoglycans of uterine fibroids and keloid scars: similarity in their proteoglycan composition

(2012) David A. Carrino et al.   BIOCHEMICAL JOURNAL

Control of progesterone receptor transcriptional synergy by SUMOylation and deSUMOylation

(2012) Hany A Abdel-Hafiz et al.   BMC MOLECULAR BIOLOGY

Progesterone Receptor-A and -B Have Opposite Effects on Proinflammatory Gene Expression in Human Myometrial Cells: Implications for Progesterone Actions in Human Pregnancy and Parturition

(2012) Huiqing Tan et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Ulipristal Acetate versus Placebo for Fibroid Treatment before Surgery

(2012) Jacques Donnez et al.   NEW ENGLAND JOURNAL OF MEDICINE

Ulipristal Acetate versus Leuprolide Acetate for Uterine Fibroids

(2012) Jacques Donnez et al.   NEW ENGLAND JOURNAL OF MEDICINE

Differential Regulation of Breast Cancer-Associated Genes by Progesterone Receptor Isoforms PRA and PRB in a New Bi-Inducible Breast Cancer Cell Line

(2012) Junaid A. Khan et al.   PLoS One

Cancer statistics, 2011

(2011) Rebecca Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Consensus on women’s health aspects of polycystic ovary syndrome (PCOS): the Amsterdam ESHRE/ASRM-Sponsored 3rd PCOS Consensus Workshop Group

(2011) Bart C.J.M. Fauser et al.   FERTILITY AND STERILITY

Increased Activation of the PI3K/AKT Pathway Compromises Decidualization of Stromal Cells from Endometriosis

(2011) Xunqin Yin et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

ck2-Dependent Phosphorylation of Progesterone Receptors (PR) on Ser81 Regulates PR-B Isoform-Specific Target Gene Expression in Breast Cancer Cells

(2011) C. R. Hagan et al.   MOLECULAR AND CELLULAR BIOLOGY

Ligand-Dependent Degradation of SRC-1 Is Pivotal for Progesterone Receptor Transcriptional Activity

(2011) Larbi Amazit et al.   MOLECULAR ENDOCRINOLOGY

Progesterone Receptor-B Induction of BIRC3 Protects Endometrial Cancer Cells from AP1-59-Mediated Apoptosis

(2011) Nikki L. Neubauer et al.   Hormones & Cancer

Forkhead Transcription Factor FOXO1 is a Direct Target of Progestin to Inhibit Endometrial Epithelial Cell Growth

(2010) S. Kyo et al.   CLINICAL CANCER RESEARCH

Efficacy and tolerability of CDB-2914 treatment for symptomatic uterine fibroids: a randomized, double-blind, placebo-controlled, phase IIb study

(2010) Lynnette K. Nieman et al.   FERTILITY AND STERILITY

Association of progesterone receptor polymorphism with idiopathic recurrent pregnancy loss in Taiwanese Han population

(2010) Mei-Tsz Su et al.   JOURNAL OF ASSISTED REPRODUCTION AND GENETICS

Human Labor Is Associated with Reduced Decidual Cell Expression of Progesterone, But Not Glucocorticoid, Receptors

(2010) C. J. Lockwood et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Modulation of ATP-induced calcium signaling by progesterone in T47D-Y breast cancer cells

(2010) Karen L. Lee et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Endometriosis

(2010) Linda C. Giudice   NEW ENGLAND JOURNAL OF MEDICINE

CDB-2914 for Uterine Leiomyomata Treatment

(2010) Eric D. Levens et al.   OBSTETRICS AND GYNECOLOGY

Progesterone Receptors in the Human Pregnancy Uterus

(2010) Sam Mesiano et al.   Reproductive Sciences

Cell-Type Specific Actions of Progesterone Receptor Modulators in the Regulation of Uterine Leiomyoma Growth

(2010) Shigeki Yoshida et al.   SEMINARS IN REPRODUCTIVE MEDICINE

Progesterone stimulates mitochondrial activity with subsequent inhibition of apoptosis in MCF-10A benign breast epithelial cells

(2009) Millie A. Behera et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Clinical utility of progesterone receptor modulators and their effect on the endometrium

(2009) Irving M Spitz   CURRENT OPINION IN OBSTETRICS & GYNECOLOGY

The Progesterone Receptor Coactivator Hic-5 Is Involved in the Pathophysiology of Endometriosis

(2009) Lusine Aghajanova et al.   ENDOCRINOLOGY

Myometrial cells undergo fibrotic transformation under the influence of transforming growth factor β-3

(2009) Doina S. Joseph et al.   FERTILITY AND STERILITY

Progestins Activate the AKT Pathway in Leiomyoma Cells and Promote Survival

(2009) Anna V. Hoekstra et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Endometrial changes from short-term therapy with CDB-4124, a selective progesterone receptor modulator

(2009) Olga B Ioffe et al.   MODERN PATHOLOGY

Overexpression of progesterone receptor A isoform in mice leads to endometrial hyperproliferation, hyperplasia and atypia

(2009) M.C. Fleisch et al.   MOLECULAR HUMAN REPRODUCTION

De novo synthesis of estrogen in pregnant uterus is critical for stromal decidualization and angiogenesis

(2009) A. Das et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Systematic Expression Analysis and Antibody Screening Do Not Support the Existence of Naturally Occurring Progesterone Receptor (PR)-C, PR-M, or Other Truncated PR Isoforms

(2008) Annemarie Samalecos et al.   ENDOCRINOLOGY

Upregulation of ATP-sensitive potassium channels for estrogen-mediated cell proliferation in human uterine leiomyoma cells

(2008) Sung-Hee Park et al.   GYNECOLOGICAL ENDOCRINOLOGY

Selective progesterone receptor modulator asoprisnil down-regulates collagen synthesis in cultured human uterine leiomyoma cells through up-regulating extracellular matrix metalloproteinase inducer

(2008) A. Morikawa et al.   HUMAN REPRODUCTION

Effects of the Selective Progesterone Receptor Modulator Asoprisnil on Uterine Artery Blood Flow, Ovarian Activity, and Clinical Symptoms in Patients with Uterine Leiomyomata Scheduled for Hysterectomy

(2008) Julia Wilkens et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Early effects of high concentrations of progesterone and Mifepristone A gene expression study of endometrial cancer cells (Ishikawa)

(2008) Anne Ørbo et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

The spectrum of endometrial pathology induced by progesterone receptor modulators

(2008) George L Mutter et al.   MODERN PATHOLOGY

Progesterone Receptor Rapid Signaling Mediates Serine 345 Phosphorylation and Tethering to Specificity Protein 1 Transcription Factors

(2008) Emily J. Faivre et al.   MOLECULAR ENDOCRINOLOGY

Progesterone receptor modulator CDB-2914 induces extracellular matrix metalloproteinase inducer in cultured human uterine leiomyoma cells

(2008) Q. Xu et al.   MOLECULAR HUMAN REPRODUCTION

Cervical dysplasia and cancer and the use of hormonal contraceptives in Jamaican women

(2008) Norma McFarlane-Anderson et al.   BMC Womens Health

The Regulation and Function of the Forkhead Transcription Factor, Forkhead Box O1, Is Dependent on the Progesterone Receptor in Endometrial Carcinoma

(2007) Erin C. Ward et al.   ENDOCRINOLOGY

Gene expression in endometrial cancer cells (Ishikawa) after short time high dose exposure to progesterone

(2007) Ruth H. Paulssen et al.   STEROIDS