Čedomir Stevčić

Serbia n/a

Article

Commented on Intakes of Lutein, Zeaxanthin, and Other Carotenoids and Age-Related Macular Degeneration During 2 Decades of Prospective Follow-up
This long-term study (from 1984 until May 31, 2010, and from 1986 until January 31, 2010) of more than 100,000 subjects (63 443 women and 38 603 men, aged 50 years or older) found that having higher amounts of carotenoids in the blood is associated with up to a 25% lower risk for Age-Related Macular Degeneration (AMD).

Article

Commented on Organic Foods for Cancer Prevention—Worth the Investment?
This large, prospective, epidemiological study conducted by French scientists shows a 25% decrease in overall cancer risk from relatively high levels of organic food consumption, compared to little or no organic food consumption, due to the reduced exposure to dietary pesticides.

Article

Commented on Effect of Low-Intensity Aerobic Exercise on Insulin-Like Growth Factor-I and Insulin-Like Growth Factor-Binding Proteins in Healthy Men
The authors discovered that low-intensity aerobic training reduced the circulating levels of insulin-like growth factor 1 (IGF1) by 9% and improved insulin sensitivity by 20%.

Article

Commented on Circulating Levels of Insulin-like Growth Factor 1 and Insulin-like Growth Factor Binding Protein 3 Associate With Risk of Colorectal Cancer Based on Serologic and Mendelian Randomization Analyses
This UK study analyzed blood samples from almost 400,000 participants and discovered that a higher level of insulin-like growth factor 1 (IGF1) was associated with a higher risk for colorectal cancer because it is involved in activating multiple pathways that determine how aggressive a colorectal tumor may be.

Article

Commented on The Potential Effects of Phytoestrogens: The Role in Neuroprotection
The authors investigated the health effects of two soy phytoestrogens (i.e. genistein and daidzein) and found that soy consumption can suppress the development of prostate cancer.

Article

Commented on Association between Soy Isoflavone Intake and Breast Cancer Risk for Pre- and Post-Menopausal Women: A Meta-Analysis of Epidemiological Studies
This meta-analysis found that soy isoflavones lowered the risk of breast cancer in both pre- and postmenopausal women. However, this effect was found only in Asian populations and not in women in Western countries, probably because Asian women eat a lot more soy than Western women.

Article

Commented on Rituximab versus tocilizumab in rheumatoid arthritis: synovial biopsy-based biomarker analysis of the phase 4 R4RA randomized trial
By conducting a biopsy-based clinical study with 164 arthritis patients, the authors found that genes may predict how well people respond to treatments for arthritis and the molecular profiling of diseased joint tissue may considerably influence whether certain drug treatments for rheumatoid arthritis patients will work.

Article

Commented on Association of colchicine use for acute gout with clinical outcomes in acute decompensated heart failure
The authors found a new potential treatment option for heart failure with a common gout medication called colchicine (i.e. among more than 1,000 patients, patients taking the medication had a survival rate of 97.9% compared with a 93.5% survival rate for patients who did not take it).

Article

Commented on A Thromboxane A 2 Receptor-Driven COX-2–Dependent Feedback Loop That Affects Endothelial Homeostasis and Angiogenesis
The authors discovered new ways to treat cardiovascular diseases by identifying the underlying process of how a certain protein in blood vessel cells contributes to the development of vascular and cardiovascular diseases.

Article

Commented on Zanubrutinib monotherapy in relapsed/refractory indolent non-Hodgkin lymphoma
This study showed that the oral drug zanubrutinib can help most patients who had a slow-growing type of cancer known as marginal zone lymphoma as 80% of patients with a specific type of lymphoma had their tumors shrink in a clinical trial with this drug.

Article

Commented on Effect of Robot-Assisted Radical Cystectomy With Intracorporeal Urinary Diversion vs Open Radical Cystectomy on 90-Day Morbidity and Mortality Among Patients With Bladder Cancer
In this first-of-its-kind clinical trial, the authors show that robot-assisted surgery for bladder cancer removal and repair enables patients to recover much faster and spend considerably (20%) less time in the hospital.

Article

Commented on Excessive Gestational Weight Gain and Long-Term Maternal Cardiovascular Risk Profile: The Study of Women's Health Across the Nation
The authors showed that pregnant women with excessive gestational weight gain have a higher cardiovascular risk later in life.

Article

Commented on Metacognitions and brooding predict depressive symptoms in a community adolescent sample
The authors show that ruminative thinking (i.e. the thoughts we think about the thoughts we think) and thinking about how much we ruminate strengthens depressive symptoms.

Article

Commented on Predictive Value of Acute Neuroplastic Response to rTMS in Treatment Outcome in Depression: A Concurrent TMS-fMRI Trial
The authors have mapped how the brain changes throughout depression treatment, that is, what occurs in the brain when a person gets the depression treatment known as repetitive transcranial magnetic stimulation (rTMS).

Article

Commented on Overexpression of S100A9 in obesity impairs macrophage differentiation via TLR4-NFkB-signaling worsening inflammation and wound healing
The authors identified new mechanisms for chronic inflammation and wound healing issues as they found that after only one week of dieting the inflammatory response can be restored to normal without necessarily losing weight.