Čedomir Stevčić

Serbia n/a

Article

Commented on Consumption of artificially and sugar-sweetened beverages and incident type 2 diabetes in the Etude Epidémiologique auprès des femmes de la Mutuelle Générale de l'Education Nationale–European Prospective Investigation into Cancer and Nutrition cohort
The authors followed 66,118 women for 14 years, such as their consumption of drinks, and they found an association between a higher risk of type 2 diabetes and both sugar-sweetened beverages and artificially sweetened beverages.

Article

Commented on Diet Soda Intake and Risk of Incident Metabolic Syndrome and Type 2 Diabetes in the Multi-Ethnic Study of Atherosclerosis (MESA)
The authors evaluated the connection between diet soda consumption (by food frequency questionnaire between 2000 and 2002), risk of type 2 diabetes (at three follow-up examinations 2002–2003, 2004–2005, and 2005–2007), and incident metabolic syndrome with its components. The study involved 6,814 Caucasian, African American, Hispanic, and Chinese adults (aged 45–84 years). The results show that diet soda consumption was correlated with a 67% greater relative risk of incident type 2 diabetes and a 36% greater relative risk of incident metabolic syndrome compared with nonconsumption.

Article

Commented on Flavonoid intake and cardiovascular disease mortality in a prospective cohort of US adults
This large cohort study examined the association between flavonoid intake (7 flavonoid classes) and cardiovascular disease mortality among participants in the US (38,180 men and 60,289 women; average age 69-70 years) between 1999 and 2006. Men and women with the highest total flavonoid intakes had a reduced risk of fatal cardiovascular disease, especially in cases with flavonoids anthocyanidins, flavan-3-ols, flavones, flavonols, and proanthocyanidins. Stroke mortality had a stronger association with flavonoid consumption than ischemic heart disease.

Article

Commented on Dietary intakes of berries and flavonoids in relation to cognitive decline
The authors found that regular consumption of berries leads to slower rates of cognitive decline, that is, berries consumption is correlated with up to two and half years of added healthy brain function.

Article

Commented on Demethylation and Up-Regulation of an Oncogene after Hypomethylating Therapy
The authors discovered that hypomethylating agents for treating myelodysplastic syndrome could activate the gene that causes cancer by activating the oncofetal protein SALL4, so they proposed a strategy for early intervention to enhance treatment outcomes.

Article

Commented on Longitudinal relationship of baseline functional brain networks with intentional weight loss in older adults
This study can potentially assist in the development of tailored behavior-based treatments that target specific brain circuitry to aid in weight loss. The study’s aim was to determine whether the degree of weight loss after six months of a behavior-based intervention was related to connectivity within two functional networks (i.e. areas of the brain that are working together in sync) in a group of older adults with obesity (71 participants).

Article

Commented on Remission of peanut allergy is associated with rewiring of allergen‐driven T helper 2‐related gene networks
The authors discovered that particular gene networks are rewired to drive the transition from peanut allergy to clinical remission after a combination treatment of probiotic and oral peanut immunotherapy. They treated 62 children (one to 10 years old) with peanut allergies with a placebo or a probiotic treatment that included oral immunotherapy, and after 18 months, 74% of children who received the combination medication attained remission, compared to 4% of those who received a placebo.

Article

Commented on Dendritic cells can prime anti-tumor CD8+ T cell responses through major histocompatibility complex cross-dressing
The authors shed light on a critical phase in the anti-cancer immune response process: T cell priming. They discovered a new mechanism for activating cancer-killing T cells called MHC-I cross-dressing.

Article

Commented on Fecal microbiota transfer between young and aged mice reverses hallmarks of the aging gut, eye, and brain
The authors discovered that transplanting fecal microbiota from young into old mice can reverse the hallmarks of aging in the gut, eyes, and brain (i.e. the microbiota from old donors led to a loss of integrity of the lining of the gut, allowing bacterial products to cross into the circulation, which results in triggering the immune system and inflammation in the brain and eyes).

Article

Commented on Taking a One-Week Break from Social Media Improves Well-Being, Depression, and Anxiety: A Randomized Controlled Trial
Researchers from the University of Bath (UK) analyzed the mental health impacts of 154 individuals aged 18 to 72 who used social media every day by asking the control group to free up roughly nine hours of their week that would otherwise have been spent browsing through Instagram, Facebook, Twitter, and TikTok. They discovered that just one week off social media improved individuals’ overall level of well-being, as well as reduced symptoms of depression and anxiety. This action could be recommended to help people manage their mental health in the future.

Article

Commented on Nationwide and Regional PM 2.5 ‐Related Air Quality Health Benefits From the Removal of Energy‐Related Emissions in the United States
The authors discovered that more than 50,000 premature deaths could be prevented each year by eliminating air pollution emissions from energy-related activities in the United States, which could provide more than $600 billion in benefits each year from avoided illness and death.

Article

Commented on Epidemiology of accelerometer-based sleep parameters in US school-aged children and adults: NHANES 2011–2014
The authors analyzed 11,279 individuals aged 6 and older from the National Health and Nutrition Examination Survey (data gathered from 2011 to 2014) and discovered that sleep efficiency (i.e. time devote to sleeping that is actually used for sleeping) tends to reduce throughout the lifetime. They found a U-shaped pattern can be seen in a graph of how long Americans sleep over the course of their lives, with age 40 being the lowest point and hours of sleep beginning to creep back up around age 50. Their findings also suggest that females sleep longer than men on average throughout their lives, but they go to bed later and are more often interrupted.

Article

Commented on Ultrasound-controllable engineered bacteria for cancer immunotherapy
The authors developed (genetically engineered) a specialized strain of the bacteria Escherichia coli that seeks and destroys cancer cells when injected into a patient’s body, and it is sound-controlled (i.e. pulses of ultrasound can trigger them to produce anti-cancer chemicals).

Article

Commented on How much sugar is hidden in drinks marketed to children? A survey of fruit juices, juice drinks and smoothies
The authors investigated 24 smoothies, 21 fruit juices, and 158 juice drinks available in English supermarkets and discovered that the typical 15-ounce bottled smoothie delivered 65 grams of sugar, which is more than twice of the daily sugar intake recommended by the American Heart Association.

Article

Commented on Systematic review of light exposure impact on human circadian rhythm
This systematic literature review from Finland analyzed 128 articles (melatonin secretion in 122 articles and REM sleep in 13 articles) and found that a two-hour exposure to blue light (460 nm) in the evening suppresses melatonin, that is, light exposure in the evening, night, and morning affected the circadian phase of melatonin levels.