This clinical trial (12-week study with 44 patients) compared bakuchiol and retinol and discovered almost identical results as both effectively reduced wrinkles and hyperpigmentation without significant difference between the compounds. However, bakuchiol was much better tolerated than retinol with few to no adverse effects.
The authors have found that applying a bakuchiol product daily can improve the appearance of fine lines, wrinkles, and other signs of aging, and it also helps prevent new wrinkles from forming by improving skin firmness.
This modeling study from MIT suggests that the muffled environment in utero (low-frequency sounds due to the amniotic fluid and surrounding tissues) primes the brain’s ability to interpret some types of sound - this degraded sensory input is beneficial, and perhaps necessary, for auditory development. On the other hand, exposing an auditory system to a full range of frequencies from the beginning can lead to worse generalization performance on tasks that require absorbing information over longer periods of time. These findings suggest that babies born prematurely may benefit from being exposed to lower-frequency sounds rather than the full spectrum of frequencies.
The authors have extracted health record data from 111 patients (mean age, 52 years) and discovered that a type of swelling in the armpits called *Axillary lymphadenopathy* detected by breast ultrasound after COVID-19 mRNA vaccination lasts longer than reported in initial vaccine clinical trials (at least 12 weeks). Longer effects were observed with Moderna than with Pfizer vaccination, and with thicker cortical thickness.
Researchers from MIT have created a new brain tissue model that enables model drug delivery to brain tumors (i.e. nanoparticles cross the Blood-Brain Barrier) so it may be able to deliver chemotherapy drugs for glioblastoma, a fast-growing and aggressive type of cancer.
Call for a Special Issue on “Ecosystem Services, Sustainable Development, and Human and Ecosystem Health in Arctic and Cold Region Environments” in the journal ⋘Arctic, Antarctic, and Alpine Research⋙ by 31st December 2022.
This special issue focuses on the topics such as the underlying physical, chemical, geological, or ecological underpinnings of ecosystem services including climate feedbacks in cold region environments; case studies that address the socioecological, economic, or policy implications of achieving Sustainable Development Goals in the Arctic; improved methodological approaches for quantifying or upscaling ecosystem services or nature’s contributions to people in the Arctic; etc.
Link: 🔗https://think.taylorandfrancis.com/special_issues/arctic-antarctic-alpine-research/?_ga=2.234234903.866085561.1656531424-1671063712.1650551154&_gl=1*16afkza*_ga*MTY3MTA2MzcxMi4xNjUwNTUxMTU0*_ga_0HYE8YG0M6*MTY1NjUzMTQyNi4xMC4xLjE2NTY1MzE0NDUuMA..🔗
Call for a Special Issue on “Ecosystem’s Contribution to Carbon Neutrality” in the journal ⋘Ecosystem Health and Sustainability⋙ by 31st August 2023.
This special issue focuses on the topics such as Method and modeling tools of integrated assessment on ecosystem’s contribution to carbon neutrality; Theories, conceptual frameworks, and metrics of sustainable ecosystem management in the context of carbon neutrality; Case studies on how ecosystems play a role in achieving carbon neutrality; Mitigation potentials and costs of ecosystem-based solutions, including technology, know-how, and best practice; Evaluation of various policy instruments.
Link: 🔗https://think.taylorandfrancis.com/special_issues/ecosystems-carbon-neutrality/?_ga=2.234234903.866085561.1656531424-1671063712.1650551154&_gl=1*1dkvbep*_ga*MTY3MTA2MzcxMi4xNjUwNTUxMTU0*_ga_0HYE8YG0M6*MTY1NjUzMTQyNi4xMC4wLjE2NTY1MzE0MjYuMA..🔗
Call for a Special Issue on “Animals in a microbial world - contemporary perspectives” in the journal ⋘New Zealand Journal of Zoology⋙ by 12th August 2022 (Abstract) and 30th July 2023 (Manuscript).
This special issue focuses on the topics such as disease-causing microbes, microbiota of unusual or unique fauna, microbe-animal or holobiont evolution, beneficial functions of microbes in animal health and immunity, biotechnological potential of animal-associated microbes, acquisition, assembly and transmission of microbes within and across animal hosts and the environment.
Link: 🔗https://think.taylorandfrancis.com/special_issues/new-zealand-journal-zoology/?_ga=2.234234903.866085561.1656531424-1671063712.1650551154&_gl=1*1dkvbep*_ga*MTY3MTA2MzcxMi4xNjUwNTUxMTU0*_ga_0HYE8YG0M6*MTY1NjUzMTQyNi4xMC4wLjE2NTY1MzE0MjYuMA..🔗
Call for a Special Issue on “Regenerative ecotourism and A-growthism: from Anthropocentrism to Deep Ecology” in the journal ⋘Journal of Ecotourism⋙ by 30th December 2022 (Abstract) and 30th July 2023 (Manuscript).
This special issue focuses on the topics such as Ecotourism/nature-based tourism transformations and regeneration; Regenerative ecotourism and its practices; Transformational ecotourism for people and the planet; Ecotourism and biosphere politics; Sustainability ethics and ecotourism; etc.
Link: 🔗https://think.taylorandfrancis.com/special_issues/journal-ecotourism/?_ga=2.234234903.866085561.1656531424-1671063712.1650551154&_gl=1*1dkvbep*_ga*MTY3MTA2MzcxMi4xNjUwNTUxMTU0*_ga_0HYE8YG0M6*MTY1NjUzMTQyNi4xMC4wLjE2NTY1MzE0MjYuMA..🔗
The authors examined the mechanism behind the positive metabolic effects of bromelain by feeding pineapple juice to obese rats (through a high-fat diet). The results showed that the pineapple juice reduced the production of insulin and leptin, and it also changed some liver functions related to the creation and storage of fat. Hence, pineapple consumption could assist in burning fat and reversing obesity.
The authors found that bromelain could help in treating type 1 diabetes as rats who received bromelain had lower cholesterol and triglycerides, lower blood glucose, and faster wound healing than rats who did not receive bromelain.
The authors discovered that neurons with a mutation in the Neurofibromatosis type 1 (NF1) gene are hyperexcitable and that suppressing this hyperactivity with lamotrigine (an FDA-approved drug to treat epilepsy) stops tumor growth in mice.
This study is paving the way for a better understanding, prevention, and recovery of neonatal brain injuries because the authors discovered that oxidative stress over activates a glucose metabolism enzyme (GSK3β) changing hippocampal interneuron development, and impairing learning and memory. By inhibiting GSK3β in hippocampal interneurons, these cellular and cognitive deficits could be reversed.
The authors discovered that bromelain extracts lead to changes in certain biochemical pathways associated with the chronic inflammation of both rheumatoid and osteoarthritis.
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